fentanyl and f 7302

fentanyl has been researched along with f 7302 in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199014 (21.88)18.7374
1990's36 (56.25)18.2507
2000's12 (18.75)29.6817
2010's2 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chi, ZQ; Masuo, Y; Pélaprat, D; Rostène, W; Wang, H1
Lin, FS; Wang, CQ; Zhu, GY2
Chi, ZQ; Gu, JJ; Zhao, GM1
Yang, HQ; Zhang, KM; Zhao, ZQ2
Brine, GA; Carroll, FI; Jacobson, AE; Rice, KC; Rothman, RB; Seggel, M; Xu, H1
Chi, ZQ; Pélaprat, D; Roques, BP; Rostène, W; Vanhove, A; Wang, H1
Hu, ST; Xu, T1
Chi, ZQ; Kopp, N; Pélaprat, D; Roques, BP; Rostène, W; Sarrieau, A; Vanhove, A; Wang, H1
Chi, ZQ; Jin, WQ; Zhao, GM; Zheng, WJ; Zhou, HY1
Chen, JQ; Chi, ZQ; Jin, WQ1
Nie, ZZ; Wang, CQ; Zhang, KG1
Chen, J; Chi, ZQ; Xu, H; Yao, YH; Zhu, YC1
Chi, ZQ; Yao, YH1
Chi, ZQ; Li, GF; Xu, H; Yao, YH1
Ge, BL; Wang, CH; Wu, CR; Zhu, YX1
Chi, ZQ; Zheng, WJ; Zhou, J2
Chen, J; Chi, ZQ; Xu, H1
Chi, ZQ; Li, GF; Ye, SZ1
Chen, XJ; Chi, ZQ; Jin, WQ1
Chen, WL; Chen, XJ; Chi, ZQ; Huang, ZM; Li, ZG; Zhang, HP; Zheng, WJ; Zhou, J1
Li, ZY; Liu, JZ; Ni, CH; Tang, GZ; Wu, YZ; Zhao, XL; Zhou, DH1
Chou, DP; Huang, ZM; Wu, RQ; Zhu, YC1
Dai, QY; Fang, SN; Ge, BJ; Huang, ZM; Li, QZ; Ni, CH; Wu, RQ; Zhou, DH1
Chen, J; Chen, XJ; Chi, ZQ; Ji, RY; Jin, WQ; Wang, ZX; Zhu, YC1
Li, XY; Xu, SF; Zhu, CB; Zhu, YH1
Cui, X; Han, JS; Xu, W1
Chen, SZ; Han, JS1
Brine, GA; Carroll, FI; Liu, Y; Rothman, RB; Singh, P; Stark, PA; Xu, H1
Chen, XJ; Chi, ZQ; Lin, SY; Lu, YF; Tong, CX; Wei, AL; Zhou, DH1
Shi, GG; Wei, DS; Xu, SF1
Chi, ZQ; Li, GF; Lu, YF1
Barth, A; Brandt, W; Höltje, HD1
Brine, GA; Carroll, FI; Ni, Q; Partilla, JS; Rothman, RB; Stark, PA; Xu, H1
Han, JS; Han, NL; Zhang, LJ1
Han, JS; Sun, YH; Zhou, Y1
Han, JS; Sun, YH; Zhang, ZW; Zhou, Y1
Han, JS; Kang, HG; Li, CQ; Liu, NJ; Xu, C; Xu, T; Yu, YX1
Brine, GA; Carroll, FI; Chen, C; Lai, J; Liu-Chen, LY; Lu, YF; Partilla, JS; Porreca, F; Rice, KC; Rothman, RB; Sadee, W; Xu, H1
Cheung, P; Li, JG; Liu-Chen, LY; Raffa, RB; Tzeng, TB1
Chen, KX; Chi, ZQ; Ji, RY; Jiang, HL; Tang, Y; Wang, ZX1
Chen, J; Chen, XJ; Chi, ZQ; Jin, WQ; Wang, ZX1
Chen, KX; Ji, RY; Jiang, HL; Rong, SB; Wang, QM; Zhao, SR; Zhu, YC1
Brine, GA; Carroll, FI; Chen, KX; Chi, ZQ; Lu, YF; Partilla, JS; Rice, KC; Rothman, RB; Wang, JB; Xu, H; Zheng, QX1
Chen, J; Chi, ZQ; Li, CL; Pei, G; Shen, QX; Wang, CH; Wei, Q; Zhou, DH1
Bi-Yi, C; Jie, C; Wen-Qiao, J; Xin-Jian, C; You-Cheng, Z; Zhi-Qiang, C1
Chi, ZQ; Guo, GW; He, Y; Jin, WQ; Zhu, YC; Zou, Y1
Chen, ZW; Han, JS; Wang, Y; Yang, K1
Li, XY; Wu, T1
Cao, Y; Chen, KX; Gu, JD; Huang, XQ; Ji, RY; Jiang, HL; Luo, XM; Rong, SB; Tan, XJ; Zhu, YC1
Chi, ZQ; Jin, WQ; Jin, XL; Li, GF; Zhou, DH1
Chen, XJ; Chi, ZQ; Guo, GW; Jin, WQ; Liu, ZH; Zhang, HP; Zhu, YC1
Han, JS; Wang, XM; Wang, Y1
Chen, BY; Chen, XJ; Chi, ZQ; Jin, WQ; Zhu, YC1
Chen, J; Chen, LW; Chi, ZQ; Feng, YP; Xu, XJ; Zhou, DH1
Can, G; De-He, Z; Jie, C; Li-Wei, C; Qiang, W; Xue-Jun, X; Zhi-Qiang, C1
Che, LW; Chen, J; Chi, ZQ; Gao, C; Xu, XJ1
Chen, J; Chen, LW; Chi, ZQ; Gao, C; Tao, YM; Xu, XJ1
Chen, XJ; Chi, ZQ; He, Y; Jin, WQ; Liu, ZH; Shen, QX1
Dong, H; Han, J; Wang, X; Xu, G; Yu, Y; Zhang, D; Zhang, M1
Chi, ZQ; Liu, JG; Sun, JF; Tao, YM; Wang, YH; Xu, XJ1
Bardel, C; Chatron, N; Huissoud, C; Massoud, M; Nouchy, M; Raymond, L; Sanlaville, D; Schluth-Bolard, C1

Other Studies

64 other study(ies) available for fentanyl and f 7302

ArticleYear
Effect of brain lesions on [3H]ohmefentanyl binding site densities in the rat striatum and substantia nigra.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:9

    Topics: Animals; Brain Injuries; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Male; Rats; Rats, Wistar; Receptors, Opioid; Substantia Nigra

1992
[Effects of microiontophoretically applied OMF and U-50488 on spontaneous discharges of respiration related units in the region of nucleus of solitary tract of rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1992, Volume: 44, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Depression, Chemical; Electrophysiology; Female; Fentanyl; Iontophoresis; Male; Medulla Oblongata; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Respiration

1992
Effects of ohmefentanyl on CA1 field potentials in rat hippocampus slices.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:4

    Topics: Analgesics; Animals; Evoked Potentials; Fentanyl; Hippocampus; Male; Morphine; Naloxone; Rats; Rats, Wistar

1992
[Inhibition of ohmefentanyl on articular afferent-induced responses of neurons in the spinal lamina X].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:2

    Topics: Analgesics; Animals; Cats; Electric Stimulation; Female; Fentanyl; Joints; Male; Neurons, Afferent; Nociceptors; Spinal Cord

1992
RTI-4614-4: an analog of (+)-cis-3-methylfentanyl with a 27,000-fold binding selectivity for mu versus delta opioid binding sites.
    Life sciences, 1991, Volume: 48, Issue:23

    Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; In Vitro Techniques; Kinetics; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1991
[3H]ohmefentanyl preferentially binds to mu-opioid receptors but also labels sigma-sites in rat brain sections.
    European journal of pharmacology, 1991, Feb-14, Volume: 193, Issue:3

    Topics: Amino Acid Sequence; Analgesics; Animals; Autoradiography; Binding Sites; Brain; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Male; Molecular Sequence Data; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Substrate Specificity; Tritium

1991
[Relationship between central beta-endorphins and serotonin systems in mechanism of hypoxic ventilatory regulation].
    Sheng li xue bao : [Acta physiologica Sinica], 1991, Volume: 43, Issue:6

    Topics: Animals; beta-Endorphin; Fentanyl; Hypoxia; Injections, Intraventricular; Male; Naloxone; Rabbits; Respiration; Serotonin

1991
Characterization and distribution of [3H]ohmefentanyl binding sites in the human brain.
    Synapse (New York, N.Y.), 1991, Volume: 8, Issue:3

    Topics: Adult; Aged; Autoradiography; Basal Ganglia; Binding Sites; Binding, Competitive; Brain Chemistry; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Fentanyl; Humans; In Vitro Techniques; Kinetics

1991
[Pharmacokinetics of [3H]ohmefentanyl in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:5

    Topics: Animals; Blood Proteins; Fentanyl; Male; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution

1990
[Opioid dependence and tolerance in the guinea-pig ileum in vitro].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:6

    Topics: Analgesics; Animals; Drug Tolerance; Fentanyl; Guinea Pigs; Ileum; Male; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Opioid-Related Disorders

1990
Inhibition of nociceptive responses of dorsal horn neurones in the cat spinal cord by ohmefentanyl, a preferring mu opioid receptor agonist [corrected].
    Neuroscience letters, 1990, Apr-20, Volume: 112, Issue:1

    Topics: Action Potentials; Animals; Cats; Fentanyl; Narcotic Antagonists; Nociceptors; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord

1990
[Effects of microiontophoretically applied OMF on spontaneous discharges of respiration related units (RRUs) in the region of nucleus ambigus of rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1990, Volume: 42, Issue:4

    Topics: Animals; Electrophysiology; Female; Fentanyl; Iontophoresis; Male; Medulla Oblongata; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration

1990
[Effects of ohmefentanyl on rat respiration].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:3

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Female; Fentanyl; Male; Medulla Oblongata; Pons; Rats; Rats, Inbred Strains; Respiration

1989
Potent 3-methylfentanyl analogs: morphine-like catalepsy and receptor binding characteristics.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:4

    Topics: Analgesics; Animals; Catalepsy; Female; Fentanyl; Male; Mice; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, mu

1987
Inhibitory regulations of ohmefentanyl and morphine on postsynaptic dopamine receptors.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:1

    Topics: Animals; Corpus Striatum; Fentanyl; Male; Morphine; Neurons; Rats; Receptors, Dopamine; Receptors, Neurotransmitter; Rotation; Substantia Nigra

1988
[Autoradiographic distribution of [3H]ohmefentanyl binding sites in rat corpus striatum].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:3

    Topics: Analgesics; Animals; Autoradiography; Binding Sites; Corpus Striatum; Fentanyl; Hydroxydopamines; Kainic Acid; Male; Oxidopamine; Rats; Receptors, Opioid; Receptors, Opioid, mu

1988
[Effects of ohmefentanyl on the content of endorphin in pituitary and brain areas of rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:6

    Topics: Analgesia; Animals; beta-Endorphin; Brain; Catalepsy; Dynorphins; Endorphins; Enkephalin, Methionine; Fentanyl; Male; Peptide Fragments; Pituitary Gland; Radioimmunoassay; Rats; Tissue Distribution

1986
[Effects of potent analgesics, ohmefentanyl and mefentanyl, on respiration and electroencephalogram in rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:2

    Topics: Analgesics; Animals; Electroencephalography; Female; Fentanyl; Male; Rabbits; Respiration

1986
Ohmefentanyl--a new agonist for mu-opiate receptor.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1985, Volume: 28, Issue:5

    Topics: Analgesics; Animals; Binding Sites; Brain; Fentanyl; Male; Mice; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1985
[Autoradiography of [3H]ohmefentanyl binding with opiate receptors in the rat brain].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:3

    Topics: Analgesics; Animals; Autoradiography; Binding, Competitive; Brain; Fentanyl; Male; Rats; Receptors, Opioid; Receptors, Opioid, mu

1986
The choice of opioid receptor subtype in isolated preparations by ohmefentanyl.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1987, Volume: 30, Issue:2

    Topics: Analgesics; Animals; Fentanyl; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Receptors, Opioid; Receptors, Opioid, mu; Species Specificity; Vas Deferens

1987
[Effect of ohmefentanyl injection to the region of nucleus tractus solitarius on discharge of phrenic nerve in rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:4

    Topics: Analgesics; Animals; Electrophysiology; Female; Fentanyl; Male; Medulla Oblongata; Microinjections; Phrenic Nerve; Rabbits

1988
[Analgesic activity and toxicity of potent analgesics, ohmefentanyl and mefentanyl].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:3

    Topics: Analgesics; Animals; Blood Pressure; Electrocardiography; Electroencephalography; Fentanyl; Mice; Nalorphine; Rabbits; Rats

1984
[Preparation of [3H]-labelled N-[1-(beta-hydroxy beta-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropionamide and studies of its binding with opiate receptors of mouse brain].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1982, Volume: 17, Issue:9

    Topics: Analgesics; Animals; Brain; Fentanyl; Mice; Receptors, Opioid; Tritium

1982
[Studies on potent analgesics. VII. Synthesis and analgesic activity of diastereoisomers of 1-beta-hydroxy-3-methylfentanyl (7302) and related compounds].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:12

    Topics: Analgesics; Animals; Fentanyl; Male; Mice; Stereoisomerism; Structure-Activity Relationship

1983
[Studies on potent analgesics. V. Synthesis and analgesic activity of the ester derivatives of N-(1-(2-hydroxy-2-phenylethyl)-3-methyl-4-piperidyl)-N-phenylpropan amide (7302)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:11

    Topics: Analgesics; Animals; Female; Fentanyl; Mice

1983
Stereoisomers of N-[1-hydroxy-(2-phenylethyl)-3-methyl-4-piperidyl]- N-phenylpropanamide: synthesis, stereochemistry, analgesic activity, and opioid receptor binding characteristics.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Analgesics; Animals; Crystallography, X-Ray; Female; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle, Smooth; Rabbits; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship; Vas Deferens

1995
Binding sites of mu receptor increased when acupuncture analgesia was enhanced by droperidol: an autoradiographic study.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:4

    Topics: Acupuncture Analgesia; Analgesics; Animals; Autoradiography; Binding Sites; Brain; Droperidol; Fentanyl; Male; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1995
Spinal serotonin IA and IC/2 receptors mediate supraspinal mu opioid-induced analgesia.
    Neuroreport, 1994, Dec-20, Volume: 5, Issue:18

    Topics: Analgesia; Animals; Brain; Fentanyl; Injections, Intraventricular; Injections, Spinal; Male; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, mu; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord

1994
Protein c-fos induction in rat brain and spinal dorsal horn by sincalide and opioids in vitro.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:5

    Topics: Animals; Brain; Dynorphins; Fentanyl; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sincalide; Spinal Cord

1994
Enantiomers of diastereomeric cis-N-[1-(2-hydroxy-2-phenylethyl)- 3-methyl-4-piperidyl]-N-phenylpropanamides: synthesis, X-ray analysis, and biological activities.
    Journal of medicinal chemistry, 1995, Apr-28, Volume: 38, Issue:9

    Topics: Analgesics; Animals; Crystallography, X-Ray; Fentanyl; Macaca mulatta; Magnetic Resonance Spectroscopy; Mice; Rats; Stereoisomerism

1995
Monoclonal antibodies specific for ohmefentanyl.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Female; Fentanyl; Guinea Pigs; Hybridomas; Ileum; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid

1994
[Effect of agonists of opioid receptor on coronary arterial strips in porcine].
    Sheng li xue bao : [Acta physiologica Sinica], 1994, Volume: 46, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Coronary Vessels; Fentanyl; Haloperidol; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Pyrrolidines; Receptors, Opioid; Swine

1994
Characterization and distribution of mu opioid receptors in rabbit cerebellum.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:6

    Topics: Animals; Autoradiography; Binding Sites; Cerebellum; Etorphine; Female; Fentanyl; Male; Rabbits; Radioligand Assay; Receptors, Opioid, mu

1993
A new consistent model explaining structure (conformation)-activity relationships of opiates with mu-selectivity.
    Drug design and discovery, 1993, Volume: 10, Issue:4

    Topics: Analgesics; Crystallography, X-Ray; Fentanyl; Models, Molecular; Molecular Conformation; Narcotics; Phenazocine; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Tomography, Emission-Computed

1993
Stereochemical requirements for pseudoirreversible inhibition of opioid mu receptor binding by the 3-methylfentanyl congeners, RTI-46144 and its enantiomers: evidence for different binding domains.
    Synapse (New York, N.Y.), 1993, Volume: 15, Issue:4

    Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Fentanyl; Ligands; Molecular Conformation; Rats; Receptors, Opioid, mu; Stereoisomerism

1993
Regulation by lithium of the antagonistic effect of cholecystokinin octapeptide on ohmefentanyl-induced antinociception.
    Neuropharmacology, 1994, Volume: 33, Issue:1

    Topics: Analgesics; Animals; Fentanyl; Injections, Spinal; Lithium; Male; Nociceptors; Pain Measurement; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Opioid, mu; Sincalide

1994
[Potentiation of morphine- and ohmefentanyl-induced analgesia by cholecystokinin receptor antagonists in rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1993, Volume: 45, Issue:3

    Topics: Analgesics; Animals; Benzodiazepinones; Devazepide; Fentanyl; Morphine; Pain Threshold; Phenylurea Compounds; Rats; Rats, Wistar; Receptors, Cholecystokinin; Spinal Cord

1993
Increased release of immunoreactive cholecystokinin octapeptide by morphine and potentiation of mu-opioid analgesia by CCKB receptor antagonist L-365,260 in rat spinal cord.
    European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3

    Topics: Analgesia; Analgesics; Animals; Benzodiazepinones; Devazepide; Dose-Response Relationship, Drug; Fentanyl; Injections, Spinal; Male; Morphine; Naloxone; Nociceptors; Pain Threshold; Phenylurea Compounds; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Cholecystokinin; Receptors, Opioid, mu; Sincalide; Spinal Cord; Subarachnoid Space

1993
Cholecystokinin octapeptide reverses mu-opioid-receptor-mediated inhibition of calcium current in rat dorsal root ganglion neurons.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:3

    Topics: Animals; Calcium Channel Blockers; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Ganglia, Spinal; Ion Channel Gating; Male; Neurons; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide

1995
Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor.
    Synapse (New York, N.Y.), 1998, Volume: 28, Issue:2

    Topics: Affinity Labels; Analgesics; Analgesics, Opioid; Animals; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Fentanyl; Melphalan; Membrane Proteins; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Opioid, mu; Recombinant Fusion Proteins; Stereoisomerism

1998
Apparent thermodynamic parameters of ligand binding to the cloned rat mu-opioid receptor.
    European journal of pharmacology, 1998, Aug-07, Volume: 354, Issue:2-3

    Topics: Analgesics; Animals; Binding, Competitive; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Ligands; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Pentazocine; Peptide Fragments; Peptides; Radioligand Assay; Rats; Receptors, Opioid, mu; Somatostatin; Sufentanil; Thermodynamics; Time Factors

1998
Molecular modeling of mu opioid receptor and its interaction with ohmefentanyl.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:2

    Topics: Amino Acid Sequence; Analgesics; Binding Sites; Fentanyl; Models, Molecular; Molecular Sequence Data; Receptors, Opioid, mu; Sequence Alignment

1996
Analgesic activity and selectivity for opioid receptors of enantiomers of ohmefentanyl.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:5

    Topics: Analgesics; Animals; Female; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Rabbits; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Vas Deferens

1996
Interaction models of 3-methylfentanyl derivatives with mu opioid receptors.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:2

    Topics: Analgesics; Drug Interactions; Fentanyl; Models, Molecular; Receptors, Opioid, mu; Structure-Activity Relationship

1997
Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligands.
    Synapse (New York, N.Y.), 1999, Volume: 32, Issue:1

    Topics: Animals; Cloning, Molecular; COS Cells; Fentanyl; Histidine; Ligands; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Rats; Receptors, Opioid, mu; Stereoisomerism; Tryptophan; Tyrosine

1999
Human mu-opioid receptor overexpressed in baculovirus system and its pharmacological characterizations.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:3

    Topics: Animals; Baculoviridae; Cells, Cultured; Cyclic AMP; Diprenorphine; Etorphine; Fentanyl; Gene Expression; Insecta; Radioligand Assay; Receptors, Opioid, mu; Transfection

1998
Analgesic activity and selectivity of isothiocyanate derivatives of fentanyl analogs for opioid receptors.
    Life sciences, 1999, Volume: 65, Issue:15

    Topics: Amides; Analgesics, Opioid; Animals; Fentanyl; Isothiocyanates; Male; Mice; Muscle Contraction; Nociceptors; Pain Measurement; Receptors, Opioid; Receptors, Opioid, delta; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Vas Deferens

1999
Comparison of physical dependence of ohmefentanyl stereoisomers in mice.
    Life sciences, 2000, Volume: 67, Issue:2

    Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fentanyl; Male; Mice; Morphine Dependence; Stereoisomerism; Substance Withdrawal Syndrome; Substance-Related Disorders

2000
The metabolic evidence of synergistic effect between ohmefentanyl and [D-Pen2, D-Pen5] enkephalin on differentiated SH-SY5Y cells in humans.
    Neuroscience letters, 2001, Feb-09, Volume: 298, Issue:3

    Topics: Acids; Analgesics; Analgesics, Opioid; Animals; Cell Differentiation; CHO Cells; Cricetinae; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Neuroblastoma; Neurons; Tumor Cells, Cultured

2001
Evidence for mu opioid receptor on mouse spleen lymphocytes.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:9

    Topics: Animals; Cell Division; Female; Fentanyl; Mice; Mice, Inbred ICR; Naloxone; Receptors, Opioid, mu; Spleen; T-Lymphocytes

1999
Molecular modeling on solvent effect and interaction mechanism of fentanyl analogs to mu-opioid receptor.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:1

    Topics: Analgesics; Binding Sites; Drug Interactions; Fentanyl; Models, Molecular; Receptors, Opioid, mu; Solvents; Structure-Activity Relationship

2000
[Effects of ohmefentanyl at anesthetic dose on plasma levels of corticosterone, cortisol and antidiuretic hormone in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:3

    Topics: Analgesics; Animals; Corticosterone; Fentanyl; Male; Rats; Stress Disorders, Post-Traumatic; Vasopressins

1997
Quantitative comparison of ohmefentanyl isomers induced conditioning place preference in mice.
    Life sciences, 2001, Apr-13, Volume: 68, Issue:21

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Conditioning, Operant; Dose-Response Relationship, Drug; Fentanyl; Injections, Subcutaneous; Isomerism; Male; Mice; Mice, Inbred Strains; Morphine; Reinforcement, Psychology

2001
Discrimination between peptide and non-peptide opioid agonists on the transcription of opioid receptors in two cell lines.
    Life sciences, 2001, May-04, Volume: 68, Issue:24

    Topics: Benzamides; Cell Line; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Piperazines; Polymerase Chain Reaction; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger; Transcription, Genetic

2001
Analgesic activity and opioid receptor selectivity of stereoisomers of ohmefentanyl isothiocyanate.
    European journal of pharmacology, 2001, Jul-27, Volume: 424, Issue:3

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Fentanyl; Guinea Pigs; Ileum; In Vitro Techniques; Isothiocyanates; Male; Mice; Muscle Contraction; Nociceptors; Pain; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Vas Deferens

2001
Analysis of binding domain and function of chimeric mu/kappa opioid receptors to ohmefentanyl stereoisomers.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:11

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cyclic AMP; Dynorphins; Fentanyl; Peptide Fragments; Protein Structure, Tertiary; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Stereoisomerism

2001
Homodimerization of human mu-opioid receptor overexpressed in Sf9 insect cells.
    Protein and peptide letters, 2002, Volume: 9, Issue:2

    Topics: Animals; Baculoviridae; Blotting, Western; Cell Line; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fentanyl; GTP-Binding Proteins; Humans; Insecta; Ligands; Narcotics; Peptides; Receptors, Opioid, mu; Sodium Dodecyl Sulfate; Time Factors

2002
Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm.
    Cell research, 2003, Volume: 13, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fentanyl; Hippocampus; Ketamine; Male; Mice; Morphine; Morphine Dependence; Phosphorylation; Reward; Stereoisomerism; Substance Withdrawal Syndrome; Substance-Related Disorders

2003
Effects of ohmefentanyl stereoisomers on phosphorylation of cAMP- response element binding protein in cultured rat hippocampal neurons.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:12

    Topics: Analgesics; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Fentanyl; Hippocampus; Morphine; Naloxone; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Signal Transduction; Stereoisomerism

2003
Effect of chronic treatment of ohmefentanyl stereoisomers on cyclic AMP formation in Sf9 insect cells expressing human mu-opioid receptors.
    Life sciences, 2004, Apr-30, Volume: 74, Issue:24

    Topics: Analgesics; Animals; Binding, Competitive; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Fentanyl; Humans; Mice; Morphine Dependence; Naloxone; Receptors, Opioid, mu; Spodoptera; Stereoisomerism; Transfection

2004
Orphanin FQ antagonizes the inhibition of Ca(2+) currents induced by mu-opioid receptors.
    Journal of molecular neuroscience : MN, 2005, Volume: 25, Issue:1

    Topics: Analgesics; Animals; Calcium; Calcium Channels; Fentanyl; Ganglia, Spinal; Male; Neurons; Nociceptin; Nociceptin Receptor; Opioid Peptides; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction

2005
Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:4

    Topics: Analgesics, Opioid; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Endocytosis; Etorphine; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Opioid-Related Disorders; Receptors, Opioid, mu

2010
Comment on "Trisomy 21 noninvasive prenatal testing for twin pregnancies".
    Prenatal diagnosis, 2019, Volume: 39, Issue:7

    Topics: Down Syndrome; Female; Fentanyl; Humans; Pregnancy; Pregnancy, Twin; Prenatal Diagnosis; Trisomy

2019