exp3174 has been researched along with pd 123319 in 13 studies
| Studies (exp3174) | Trials (exp3174) | Recent Studies (post-2010) (exp3174) | Studies (pd 123319) | Trials (pd 123319) | Recent Studies (post-2010) (pd 123319) |
|---|---|---|---|---|---|
| 236 | 29 | 43 | 894 | 6 | 175 |
| Protein | Taxonomy | exp3174 (IC50) | pd 123319 (IC50) |
|---|---|---|---|
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.21 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (69.23) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bennett, T; Gardiner, SM; Kemp, PA; Widdop, RE | 2 |
| Bennett, T; Gardiner, SM; Widdop, RE | 1 |
| Chiu, AT; Keiser, J; Madison, AB; Nishimura, H; Patton, CM; Walker, OE | 1 |
| Arendshorst, WJ; Chatziantoniou, C; Kurtz, A; Ruan, X; Wagner, C | 1 |
| Fujimori, A; Inagaki, O; Kusayama, T; Okazaki, T; Satoh, Y; Shibasaki, M; Takanashi, M; Tokioka, T; Uchida, W; Yanagisawa, I | 1 |
| Heller, J; Horácek, V | 1 |
| Freel, RW; Hatch, M; Vaziri, ND | 1 |
| Cheung, PK; Saward, L; Wilson, DP; Zahradka, P | 1 |
| Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR | 1 |
| Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R | 1 |
| Oberhauser, V; Rump, LC; Sellin, L; Stegbauer, J; Vonend, O | 1 |
| Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G | 1 |
13 other study(ies) available for exp3174 and pd 123319
| Article | Year |
|---|---|
Inhibition of the haemodynamic effects of angiotensin II in conscious rats by AT2-receptor antagonists given after the AT1-receptor antagonist, EXP 3174.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Pyridines; Rats; Regional Blood Flow; Tetrazoles | 1992 |
Central administration of PD 123319 or EXP-3174 inhibits effects of angiotensin II.
Topics: Angiotensin II; Animals; Brain; Hemodynamics; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred Strains; Substance P; Tetrazoles | 1993 |
Effects of angiotensin II AT1- or AT2-receptor antagonists on drinking evoked by angiotensin II or water deprivation in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Drinking; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Brattleboro; Tetrazoles; Water Deprivation | 1994 |
Novel angiotensin receptor subtypes in fowl.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Blood Pressure; Cell Membrane; Chickens; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Receptors, Angiotensin; Reserpine; Tetrazoles | 1994 |
Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cloning, Molecular; Culture Techniques; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enalaprilat; Gene Expression Regulation; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Artery; Renal Circulation; Ribonucleases; RNA, Messenger; Sodium, Dietary; Tetrazoles; Vasoconstrictor Agents | 1997 |
Pharmacological profile of YM358, a novel nonpeptide angiotensin AT1 receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Cattle; Decerebrate State; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1997 |
Effect of PD 123319, an AT-2 antagonist, on renal function of the anesthetized dog: comparison with EXP 3174, an AT-1 blocker.
Topics: Angiotensin Receptor Antagonists; Animals; Diuresis; Dogs; Drug Combinations; Glomerular Filtration Rate; Imidazoles; Injections, Intra-Arterial; Kidney; Losartan; Male; Natriuresis; Pyridines; Renal Circulation; Tetrazoles | 1997 |
Losartan antagonism of angiotensin-II-induced potassium secretion across rat colon.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Colon; Dose-Response Relationship, Drug; Drug Antagonism; Extracellular Space; Hydrolysis; Imidazoles; In Vitro Techniques; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Tetrazoles | 1998 |
Angiotensin II receptor antagonists prevent neointimal proliferation in a porcine coronary artery organ culture model.
Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cell Division; Coronary Disease; Coronary Vessels; Culture Techniques; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Recurrence; Swine; Tetrazoles | 1999 |
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan | 2000 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Imidazoles; Kidney; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WF; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents | 2005 |
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2016 |