eglumetad and glycine
eglumetad has been researched along with glycine in 12 studies
Compound Research Comparison
| Studies (eglumetad) | Trials (eglumetad) | Recent Studies (post-2010) (eglumetad) | Studies (glycine) | Trials (glycine) | Recent Studies (post-2010) (glycine) |
|---|---|---|---|---|---|
| 190 | 5 | 48 | 35,163 | 756 | 8,415 |
Protein Interaction Comparison
| Protein | Taxonomy | eglumetad (IC50) | glycine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.4852 | |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | 106 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | 128 |
Research
Studies (12)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Kemp, JA; Knoflach, F | 1 |
| Johnson, BG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA | 1 |
| Anwyl, R; Huang, LQ; Kilbride, J; Rowan, MJ | 1 |
| Mathis, C; Ungerer, A | 1 |
| Battaglia, G; Bond, A; Bruno, V; Clark, BP; Harris, JR; Kingston, AE; Lodge, D; Monn, JA; Nicoletti, F; O'Neill, MJ; Schoepp, DD | 1 |
| Konieczny, J; Lorenc-Koci, E; Ossowska, K; Pilc, A; Wolfarth, S | 1 |
| O'Neill, MJ | 1 |
| Anwyl, R; Kilbride, J; Rowan, MJ; Rush, AM | 1 |
| Chamberlain, M; Johnson, MP; Kelly, G | 1 |
| Blanco-Urgoiti, J; Collado, I; Espinosa, JF; Johnson, BG; Kingston, AE; Mazón, A; Pedregal, C; Schoepp, DD; Wright, RA | 1 |
| Marek, GJ; Zhang, C | 1 |
Reviews
1 review(s) available for eglumetad and glycine
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
Other Studies
11 other study(ies) available for eglumetad and glycine
| Article | Year |
|---|---|
Metabotropic glutamate group II receptors activate a G protein-coupled inwardly rectifying K+ current in neurones of the rat cerebellum.
Topics: Animals; Barium; Bridged Bicyclo Compounds; Calcium; Calcium Channels; Cerebellum; Cyclopropanes; Excitatory Amino Acid Agonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Interneurons; Membrane Potentials; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Bridged Bicyclo Compounds; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; Male; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems; Stereoisomerism; Vasodilator Agents | 1998 |
Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV.
Topics: Animals; Bridged Bicyclo Compounds; Cyclopropanes; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1998 |
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors | 1999 |
Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Ischemia; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Thiophenes | 1999 |
The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity.
Topics: Animals; Bridged Bicyclo Compounds; Electromyography; Glycine; Ligands; Male; Muscle Rigidity; Parkinson Disease; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2000 |
Pharmacology and neuroprotective actions of mGlu receptor ligands.
Topics: Amino Acids; Brain; Brain Ischemia; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Glycine; Hippocampus; Humans; Kainic Acid; Ligands; Nerve Degeneration; Neuroprotective Agents; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2001 |
Presynaptic group II mGluR inhibition of short-term depression in the medial perforant path of the dentate gyrus in vitro.
Topics: Animals; Anticonvulsants; Bridged Bicyclo Compounds; Cyclopropanes; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Male; Neural Inhibition; Perforant Pathway; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2001 |
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes | 2001 |
(2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 receptor agonist with anxiolytic properties.
Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Cell Line; Cyclopropanes; Glycine; Ligands; Models, Molecular; Rats; Receptors, Metabotropic Glutamate; Reflex, Startle; Stereoisomerism | 2002 |
Group III metabotropic glutamate receptor agonists selectively suppress excitatory synaptic currents in the rat prefrontal cortex induced by 5-hydroxytryptamine2A receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Bridged Bicyclo Compounds; Glycine; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; Serotonin; Synaptic Transmission; Xanthenes | 2007 |