Compounds > diclofenac

diclofenac and gs 4071

diclofenac has been researched along with gs 4071 in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (20.00)	29.6817
2010's	4 (40.00)	24.3611
2020's	4 (40.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Bertagnin, C; Desta, S; Ding, X; Fang, Z; Gao, P; Huang, B; Jia, H; Jia, R; Ju, H; Kang, D; Kong, X; Liang, X; Liu, X; Loregian, A; Lu, H; Lu, X; Ma, X; Murugan, NA; Poongavanam, V; Sun, L; Tian, Y; Xu, W; Zhan, P; Zhang, J	1
Chen, B; Hu, Y; Lei, Z; Liu, K; Meng, P; Tian, Y; Wang, B; Wang, K; Yang, F	1
Bertagnin, C; Ding, X; Fang, Z; Gao, P; Huang, B; Jia, H; Jia, R; Kang, D; Kong, X; Liu, X; Loregian, A; Ma, X; Murugan, NA; Poongavanam, V; Sun, Z; Tian, Y; Xu, W; Zhan, P; Zhang, J	1
Cao, R; Chen, B; Lei, Z; Liu, K; Tian, Y; Wang, K; Yang, F; Zhang, K; Zhao, H; Zhao, L; Zhu, H	1
Chen, B; Lei, Z; Liu, K; Tian, Y; Wang, J; Wang, K; Yang, F; Zhang, H; Zhang, K; Zhao, H; Zhao, X; Zhu, H	1
Hu, B; Hu, Y; Jiang, S; Meng, P; Tian, Y; Wang, J; Wang, K; Ye, Z; Zhang, H; Zhao, H; Zhu, H	1
Bertagnin, C; Du, R; Guizzo, L; Hou, L; Huang, B; Jia, R; Ju, H; Kang, D; Kong, X; Li, P; Liu, X; Loregian, A; Ma, X; Murugan, NA; Poongavanam, V; Zhan, P; Zhang, Y	1

Other Studies

10 other study(ies) available for diclofenac and gs 4071

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant. Journal of medicinal chemistry, 2018, Jul-26, Volume: 61, Issue:14 Topics: Cell Line; Drug Design; Drug Resistance, Viral; Enzyme Inhibitors; Female; Humans; Male; Models, Molecular; Mutation; Neuraminidase; Oseltamivir; Protein Conformation; Safety; Viral Proteins	2018
Design, synthesis, and evaluation of carboxyl-modified oseltamivir derivatives with improved lipophilicity as neuraminidase inhibitors. Bioorganic & medicinal chemistry letters, 2018, 11-15, Volume: 28, Issue:21 Topics: Antiviral Agents; Catalytic Domain; Drug Design; Drug Stability; Enzyme Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Influenza A Virus, H5N1 Subtype; Microsomes, Liver; Molecular Docking Simulation; Neuraminidase; Oseltamivir	2018
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant. Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22 Topics: Animals; Antiviral Agents; Catalytic Domain; Dogs; Drug Design; Drug Resistance, Viral; Drug Stability; Humans; Influenza A virus; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Mutation; Neuraminidase; Nitrogen; Oseltamivir; Rats; Tissue Distribution	2018
Design, synthesis and biological evaluation of oseltamivir derivatives containing pyridyl group as potent inhibitors of neuraminidase for influenza A. European journal of medicinal chemistry, 2020, Jan-01, Volume: 185 Topics: Animals; Antiviral Agents; Dogs; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Neuraminidase; Oseltamivir; Structure-Activity Relationship	2020
Discovery of a non-zwitterionic oseltamivir analogue as a potent influenza a neuraminidase inhibitor. European journal of medicinal chemistry, 2020, Aug-15, Volume: 200 Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Microbial Sensitivity Tests; Molecular Structure; Neuraminidase; Oseltamivir; Structure-Activity Relationship; Viral Proteins	2020
Discovery of hydrazide-containing oseltamivir analogues as potent inhibitors of influenza A neuraminidase. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Humans; Hydrazines; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Mutation; Neuraminidase; Oseltamivir; Structure-Activity Relationship; Viral Proteins	2021
Identification of C5-NH Journal of medicinal chemistry, 2021, 12-23, Volume: 64, Issue:24 Topics: Animals; Antiviral Agents; Biological Availability; Chick Embryo; Computer Simulation; Half-Life; Influenza A Virus, H5N1 Subtype; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Neuraminidase; Oseltamivir; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2021