diclofenac and glycine

diclofenac has been researched along with glycine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
el-Sherif, AE; Foda, R; Norlen, LJ; Yahia, H1
Tavella, A; Ursini, G1
Dobrilla, G1
Chiloiro, M; Montanaro, S; Riezzo, G1
Andersson, TB; Bredberg, E; Eriksson, UG; Eriksson-Lepkowska, M; Frison, L; Johansson, S; Larsson, M; Thuresson, A1
Alexandova, A; Kesiova, M; Kirkova, M; Todorov, S1
Di Nardo, G; Gilardi, G; Goyal, A; Sideri, A; Tsotsou, GE1
Choi, MR; Fernandez, BE; Gorzalczany, S; Mikusic, NLR; Penna, SLD; Roson, MI; Toblli, JE; Zotta, E1
Freire, CSR; Oliveira, H; Saïdi, L; Silvestre, AJD; Vilela, C1
Akinrinde, AS; Hameed, HO1

Trials

4 trial(s) available for diclofenac and glycine

ArticleYear
Treatment of renal colic by prostaglandin synthetase inhibitors and avafortan (analgesic antispasmodic).
    British journal of urology, 1990, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Dipyrone; Drug Combinations; Female; Glycine; Humans; Indomethacin; Injections, Intramuscular; Injections, Intravenous; Kidney Diseases; Male; Middle Aged; Phenylacetates; Prospective Studies

1990
[A clinical study on the anti-inflammatory activity and gastrointestinal tolerability of amtolmetin guacyl, a new NSAID, compared with diclofenac in aged patients with osteoarticular diseases].
    La Clinica terapeutica, 1997, Volume: 148, Issue:11

    Topics: Administration, Oral; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Data Interpretation, Statistical; Diclofenac; Drug Tolerance; Female; Gastric Mucosa; Gastroscopy; Glycine; Humans; Intestinal Mucosa; Middle Aged; Monitoring, Physiologic; Osteoarthritis; Pyrroles

1997
Protective effect of amtolmetin guacyl versus placebo diclofenac and misoprostol in healthy volunteers evaluated as gastric electrical activity in alcohol-induced stomach damage.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cross-Over Studies; Diclofenac; Double-Blind Method; Electrophysiology; Ethanol; Gastric Emptying; Gastric Mucosa; Glycine; Humans; Misoprostol; Pyrroles; Stomach

2001
Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.
    Clinical pharmacokinetics, 2003, Volume: 42, Issue:8

    Topics: Administration, Oral; Adult; Aged; Amidines; Anticoagulants; Area Under Curve; Azetidines; Benzylamines; Cross-Over Studies; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Drug Interactions; Glycine; Humans; In Vitro Techniques; Infusions, Intravenous; Microsomes, Liver; Middle Aged; Nifedipine; Nordazepam; Prodrugs; Thrombin

2003

Other Studies

9 other study(ies) available for diclofenac and glycine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Nitric oxide and non steroidal antiinflammatory drugs (NSAID)-related gastroduodenal damage.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2001, Volume: 56, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gastric Mucosa; Glycine; Humans; Nitric Oxide; Peptic Ulcer; Pyrroles

2001
In vivo effects of amtolmetin guacyl on lipid peroxidation and antioxidant defence systems. Comparison with non-selective and COX-2 selective NSAIDs.
    Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catalase; Celecoxib; Colon; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastric Mucosa; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycine; Lipid Peroxidation; Liver; Male; Oxyphenonium; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfonamides; Thiobarbituric Acid Reactive Substances; Tolmetin

2007
Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Mar-19, Volume: 18, Issue:12

    Topics: Asparagine; Bacillus megaterium; Catalysis; Cytochrome P-450 Enzyme System; Diclofenac; Drug Discovery; Escherichia coli; Glutamine; Glycine; Histidine; Humans; Hydroxylation; Ibuprofen; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Tolbutamide

2012
Synthesis and Biological Evaluation of New N-(4-Substituted phenyl)glycine Derivatives as Potential Anti-inflammatory Agents.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2016, Volume: 15, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Disease Models, Animal; Drug Design; Drug Discovery; Edema; Glycine; Male; Molecular Structure; Rats, Wistar; Structure-Activity Relationship

2016
Poly(N-methacryloyl glycine)/nanocellulose composites as pH-sensitive systems for controlled release of diclofenac.
    Carbohydrate polymers, 2017, Aug-01, Volume: 169

    Topics: Cell Line; Delayed-Action Preparations; Diclofenac; Drug Carriers; Glycine; Humans; Hydrogen-Ion Concentration; Methacrylates; Spectroscopy, Fourier Transform Infrared

2017
Glycine and L-Arginine supplementation ameliorates gastro-duodenal toxicity in a rat model of NSAID (Diclofenac)-gastroenteropathy via inhibition of oxidative stress.
    Journal of basic and clinical physiology and pharmacology, 2021, Feb-08, Volume: 33, Issue:3

    Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arginine; Diclofenac; Dietary Supplements; Glycine; Hydrogen Peroxide; Oxidative Stress; Rats; Rats, Wistar

2021