Page last updated: 2024-09-02

deoxyglucose and serine

deoxyglucose has been researched along with serine in 25 studies

Compound Research Comparison

Studies
(deoxyglucose)
Trials
(deoxyglucose)
Recent Studies (post-2010)
(deoxyglucose)
Studies
(serine)
Trials
(serine)
Recent Studies (post-2010) (serine)
11,4261711,37523,9141156,084

Protein Interaction Comparison

ProteinTaxonomydeoxyglucose (IC50)serine (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)0.015
CholinesteraseEquus caballus (horse)0.016

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.00)18.7374
1990's6 (24.00)18.2507
2000's9 (36.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Fleisch, H; Guenther, HE; Guenther, HL1
Blough, HA; Ray, EK1
Yavin, E; Zeigler, BP1
Fischer, Y; Kammermeier, H; Rose, H1
Rakowska, M; Wojtczak, L1
Reizer, J; Saier, MH; Ye, JJ1
Cui, X; Neal, JW; Reizer, J; Saier, MH; Ye, JJ1
Bossenmaier, B; Häring, HU; Kellerer, M; Lammers, R; Mosthaf, L; Stoyanov, B; Strack, V1
Dufresne, SD; Goodyear, LJ; Higaki, Y; Hirshman, MF; Kahn, CR; Michael, MD; Wojtaszewski, JF1
Haruta, T; Iwata, M; Kawahara, J; Kobayashi, M; Takano, A; Uno, T; Usui, I1
Ishizawa, M; Ishizuka, T; Kajita, K; Kanoh, Y; Kawai, Y; Miura, A; Morita, H; Natsume, Y; Uno, Y; Yasuda, K1
Gagnon, A; Marette, A; Sorisky, A; Tremblay, F; Veilleux, A1
Baumgartner, F; Brodbeck, K; Häring, HU; Hennige, AM; Lehmann, R; Schaüble, M; Schleicher, ED; Weigert, C1
Beck, A; Häring, HU; Hennige, AM; Kapp, K; Lehmann, R; Moeschel, K; Mushack, J; Schleicher, E; Stefan, N; Weigert, C1
Borch, J; Harthill, JE; Mackintosh, C; Meek, SE; Morrice, N; Peggie, MW; Wong, BH1
Arias, EB; Cartee, GD; Hamada, T1
Tsichlis, PN; Tzatsos, A1
Adochio, R; Draznin, B; Kim, T; Wayne Leitner, J1
Ji, H; Qian, Z; Sheng, L; Wang, Y; Xi, L; Yang, L; Yang, R; Zhang, X; Zhao, B1
Holden, HM; Kubiak, RL1
Hansen, HH; Kristensen, LV; Sandager-Nielsen, K1
Alonso, A; Garrido, P; González, C; González, S; Morán, J1
Bennett, MV; Boric, MP; Cea, LA; Frank, M; Monyer, H; Riquelme, MA; Sáez, JC; Vega, JL; Willecke, K1
Archer, DB; Hayer, K; Stratford, M1
MacPherson, REK; Shamshoum, H; Tsiani, E; Vlavcheski, F1

Other Studies

25 other study(ies) available for deoxyglucose and serine

ArticleYear
Effects of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on rabbit articular chondrocytes in culture.
    The Biochemical journal, 1979, Nov-15, Volume: 184, Issue:2

    Topics: Aminoisobutyric Acids; Animals; Cartilage, Articular; Cell Count; Cell Division; Cells, Cultured; Clodronic Acid; Deoxyglucose; Diphosphonates; Etidronic Acid; Glycosaminoglycans; Proteoglycans; Rabbits; Serine; Sulfates

1979
The effect of herpesvirus infection and 2-deoxy-D-glucose on glycosphingolipids in BHK-21 cells.
    Virology, 1978, Jul-01, Volume: 88, Issue:1

    Topics: Cell Line; Ceramides; Deoxy Sugars; Deoxyglucose; G(M3) Ganglioside; Gangliosides; Glucosyltransferases; Glycosphingolipids; Microsomes; Palmitates; Serine; Simplexvirus; Uridine Diphosphate Glucose

1978
Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture. Serine incorporation into serine phosphoglycerides: base exchange and decarboxylation patterns.
    The Journal of biological chemistry, 1977, Jan-10, Volume: 252, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain; Calcimycin; Cell Differentiation; Cells, Cultured; Cycloheximide; Deoxyglucose; Embryo, Mammalian; Glucose; Kinetics; Mathematics; Models, Biological; Oligomycins; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Rats; Serine

1977
Possible involvement of alanine and pyruvate in the regulation of glucose transport in heart muscle cells.
    FEBS letters, 1990, Nov-12, Volume: 274, Issue:1-2

    Topics: Alanine; Animals; Biological Transport, Active; Calcium; Cells, Cultured; Deoxyglucose; Female; Heart; Kinetics; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Serine; Valine

1990
Inhibition by glucose and deoxyglucose of phosphatidylserine synthesis in Ehrlich ascites tumor cells: a possible relation to the Crabtree effect and depletion of endoplasmic reticulum Ca2+ stores.
    Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1

    Topics: Animals; Calcium; Calcium-Transporting ATPases; Carcinoma, Ehrlich Tumor; Deoxyglucose; Endoplasmic Reticulum; Glucose; Kinetics; Mice; Oxygen Consumption; Phosphatidylserines; Phospholipids; Serine; Terpenes; Thapsigargin

1995
Regulation of 2-deoxyglucose phosphate accumulation in Lactococcus lactis vesicles by metabolite-activated, ATP-dependent phosphorylation of serine-46 in HPr of the phosphotransferase system.
    Microbiology (Reading, England), 1994, Volume: 140 ( Pt 12)

    Topics: Adenosine Triphosphate; Biological Transport, Active; Carbohydrate Metabolism; Carbohydrates; Deoxyglucose; Glucosephosphates; Kinetics; Lactococcus lactis; Phosphoenolpyruvate Sugar Phosphotransferase System; Point Mutation; Serine

1994
Regulation of the glucose:H+ symporter by metabolite-activated ATP-dependent phosphorylation of HPr in Lactobacillus brevis.
    Journal of bacteriology, 1994, Volume: 176, Issue:12

    Topics: Adenosine Triphosphate; Bacterial Proteins; Biological Transport; Deoxyglucose; Glucose; Lactobacillus; Lactose; Mannose; Methylgalactosides; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Serine; Thiogalactosides

1994
The inhibitory effect of 2-deoxyglucose on insulin receptor autophosphorylation does not depend on known serine phosphorylation sites or other conserved serine residues of the receptor beta-subunit.
    FEBS letters, 1999, Apr-23, Volume: 449, Issue:2-3

    Topics: Binding Sites; Cell Line; Conserved Sequence; Deoxyglucose; Humans; Insulin; Phosphorylation; Receptor, Insulin; Serine

1999
Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:9

    Topics: Animals; Biological Transport; Deoxyglucose; Glucose; Glucose Tolerance Test; Glycogen; Glycogen Synthase; Insulin; Insulin Receptor Substrate Proteins; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Signal Transduction; Time Factors; Tyrosine

1999
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Molecular and cellular biology, 2001, Volume: 21, Issue:15

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenoviridae; Amino Acids; Animals; Biological Transport; Carrier Proteins; Cell Cycle Proteins; Cell Line; Cysteine Endopeptidases; Cytosol; Deoxyglucose; Down-Regulation; Enzyme Inhibitors; Eukaryotic Initiation Factors; Glucose; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Sirolimus; Subcellular Fractions; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tyrosine

2001
Protein kinase C (PKC) beta modulates serine phosphorylation of insulin receptor substrate-1 (IRS-1)--effect of overexpression of PKCbeta on insulin signal transduction.
    Endocrine research, 2004, Volume: 30, Issue:2

    Topics: Adipocytes; Animals; Cells, Cultured; Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Genes, Dominant; Humans; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Isoenzymes; Male; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Wistar; Serine; Signal Transduction; Transfection

2004
Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Endocrinology, 2005, Volume: 146, Issue:3

    Topics: 3-O-Methylglucose; 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Cell Membrane; Deoxyglucose; Gene Expression Regulation; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Humans; Immunoblotting; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Sirolimus; Subcellular Fractions; Time Factors; TOR Serine-Threonine Kinases

2005
Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: Animals; Blotting, Western; Cell Line; Deoxyglucose; Glucose; Humans; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Interleukin-6; Liver; Mice; Mice, Inbred C57BL; Models, Statistical; Muscle, Skeletal; Muscles; Phosphoproteins; Phosphorylation; Protein Kinase C-delta; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Serine; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Time Factors; Transfection; Tyrosine

2006
Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:8

    Topics: Adult; Animals; Biological Transport; Deoxyglucose; Down-Regulation; Female; Humans; Insulin; Insulin Antagonists; Insulin Receptor Substrate Proteins; Isoenzymes; Janus Kinase 2; Leptin; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Middle Aged; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Protein Kinase C-delta; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Serine

2006
Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.
    The Plant journal : for cell and molecular biology, 2006, Volume: 47, Issue:2

    Topics: 14-3-3 Proteins; Alanine; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Arabidopsis; Arabidopsis Proteins; Binding Sites; Cells, Cultured; Chromatography, Affinity; Deoxyglucose; Glucosyltransferases; Humans; Immunoprecipitation; Multienzyme Complexes; Mutation, Missense; Phenformin; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine

2006
Increased submaximal insulin-stimulated glucose uptake in mouse skeletal muscle after treadmill exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Exercise Test; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Serine; Threonine; Tritium

2006
Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.
    The Journal of biological chemistry, 2007, Jun-22, Volume: 282, Issue:25

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Apoptosis; Cell Line; Deoxyglucose; Glucose; Humans; Insulin Receptor Substrate Proteins; Mitochondria; Multienzyme Complexes; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Serine

2007
Knockdown of JNK rescues 3T3-L1 adipocytes from insulin resistance induced by mitochondrial dysfunction.
    Biochemical and biophysical research communications, 2009, Jan-23, Volume: 378, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Deoxyglucose; Gene Knockdown Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Mitochondrial Diseases; Mitogen-Activated Protein Kinase 8; Phosphatidylinositol 3-Kinases; Phosphorylation; Serine; Tyrosine

2009
Inhibitory effect on protein kinase Ctheta by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes.
    European journal of pharmacology, 2010, Sep-10, Volume: 642, Issue:1-3

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Biological Transport; Carotenoids; Deoxyglucose; Enzyme Activation; Glucose; I-kappa B Kinase; Inflammation; Insulin; Insulin Receptor Substrate Proteins; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mice; Palmitates; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Protein Kinase Inhibitors; Serine; Signal Transduction; Vitamin A

2010
Structural studies of AntD: an N-Acyltransferase involved in the biosynthesis of D-Anthrose.
    Biochemistry, 2012, Jan-31, Volume: 51, Issue:4

    Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Substitution; Amino Sugars; Aspartic Acid; Bacillus cereus; Bacterial Proteins; Biocatalysis; Catalytic Domain; Coenzyme A; Crystallography, X-Ray; Deoxy Sugars; Deoxyglucose; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Protein Conformation; Recombinant Proteins; Serine; Thymine Nucleotides

2012
K(v) 7 (KCNQ) channel openers normalize central 2-deoxyglucose uptake in a mouse model of mania and increase prefrontal cortical and hippocampal serine-9 phosphorylation levels of GSK3β.
    Journal of neurochemistry, 2012, Volume: 121, Issue:3

    Topics: Animals; Antimanic Agents; Autoradiography; Benzamides; Bipolar Disorder; Carbamates; Central Nervous System Stimulants; Chlordiazepoxide; Deoxyglucose; Dextroamphetamine; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Hypnotics and Sedatives; KCNQ Potassium Channels; Male; Mice; Mice, Inbred C57BL; Phenylenediamines; Phosphorylation; Prefrontal Cortex; Pyridines; Serine

2012
17β-estradiol activates glucose uptake via GLUT4 translocation and PI3K/Akt signaling pathway in MCF-7 cells.
    Endocrinology, 2013, Volume: 154, Issue:6

    Topics: 4-Chloro-7-nitrobenzofurazan; Blotting, Western; Breast Neoplasms; Cell Membrane; Deoxyglucose; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Glucose; Glucose Transporter Type 4; Humans; MCF-7 Cells; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction

2013
The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels.
    Neuropharmacology, 2013, Volume: 75

    Topics: 4-Chloro-7-nitrobenzofurazan; Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Connexins; Deoxyglucose; Ethidium; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Muscle, Skeletal; Myosins; Oleic Acids; Phosphorylation; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Serine

2013
Germination of Aspergillus niger conidia is triggered by nitrogen compounds related to L-amino acids.
    Applied and environmental microbiology, 2014, Volume: 80, Issue:19

    Topics: Amino Acids; Aspergillus nidulans; Aspergillus niger; Carbon Radioisotopes; Cysteine; Deoxyglucose; Galactose; Hyphae; Nitrogen Compounds; Serine; Spores, Fungal; Valine

2014
Rosemary extract activates AMPK, inhibits mTOR and attenuates the high glucose and high insulin-induced muscle cell insulin resistance.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2021, Volume: 46, Issue:7

    Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Cells, Cultured; Deoxyglucose; Disease Models, Animal; Enzyme Activation; Glucose Transporter Type 4; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle Fibers, Skeletal; Phosphorylation; Plant Extracts; Rats; Rosmarinus; Serine; TOR Serine-Threonine Kinases; Tyrosine

2021
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