Compounds > da 5018
Page last updated: 2024-09-05

da 5018 and capsaicin

da 5018 has been researched along with capsaicin in 8 studies

Compound Research Comparison

Studies
(da 5018)		Trials
(da 5018)		Recent Studies (post-2010)
(da 5018)		Studies
(capsaicin)		Trials
(capsaicin)		Recent Studies (post-2010) (capsaicin)
80011,2386613,410

Protein Interaction Comparison

ProteinTaxonomyda 5018 (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, SH; Kim, WB; Lee, JJ; Lee, MG; Lee, SD; Shim, HJ; Yang, J3
Kang, YS; Kim, JM1
Ahn, BO; Kim, DH; Kim, SH; Kim, WB1
Cho, H; Cho, SY; Hwang, SW; Kwon, MJ; Lee, SY; Oh, U; Shin, JS; Wang, MH1
Cha, BJ; Chung, SJ; Kim, WB; Lee, ED; Lee, MH; Shim, CK1
Blumberg, PM; Choi, HK; Jin, MK; Kang, DW; Lee, J; Pearce, LV; Ryu, H; Toth, A1

Other Studies

8 other study(ies) available for da 5018 and capsaicin

ArticleYear
Stability, blood partition, and protein binding of DA-5018, a new nonnarcotic analgesic.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 91, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Blood Cells; Blood Proteins; Capsaicin; Dogs; Drug Stability; Hydrogen-Ion Concentration; Orosomucoid; Protein Binding; Rats; Serum Albumin; Species Specificity; Temperature

1996
Determination of a new non-narcotic analgesic, DA-5018, in plasma, urine and bile by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Feb-21, Volume: 689, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Bile; Capsaicin; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Rats

1997
Pharmacokinetics of a non-narcotic analgesic, DA-5018, in rats.
    Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:2

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Biological Availability; Capsaicin; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley

1998
Permeability of a capsaicin derivative, [14C]DA-5018 to blood-brain barrier corrected with HPLC method.
    Archives of pharmacal research, 1999, Volume: 22, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Blood-Brain Barrier; Brain; Capsaicin; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Male; Permeability; Rats; Rats, Sprague-Dawley

1999
Antipruritic effect of DA-5018, a capsaicin derivative, in mice.
    Archives of pharmacal research, 1999, Volume: 22, Issue:6

    Topics: Administration, Topical; Animals; Antipruritics; Capsaicin; Drug Interactions; Leukotriene B4; Male; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Pruritus; Time Factors

1999
Differences in sensitivity of vanilloid receptor 1 transfected to human embryonic kidney cells and capsaicin-activated channels in cultured rat dorsal root ganglion neurons to capsaicin receptor agonists.
    Neuroscience letters, 2001, Feb-16, Volume: 299, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Capsaicin; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Ganglia, Spinal; Gene Expression Regulation; Humans; Ion Channels; Kidney; Neurons, Afferent; Phorbol Esters; Rats; Receptors, Drug; Transfection; TRPV Cation Channels

2001
Enhanced skin permeation of a new capsaicin derivative (DA-5018) from a binary vehicle system composed of isopropyl myristate and ethoxydiglycol.
    Archives of pharmacal research, 2001, Volume: 24, Issue:3

    Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Excipients; Male; Mice; Mice, Hairless; Myristates; Pharmaceutical Vehicles; Skin Absorption; Solubility; Solvents

2001
Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 377, Issue:2

    Topics: Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Enzyme Inhibitors; Phosphoprotein Phosphatases; Rats; Structure-Activity Relationship; TRPV Cation Channels

2008