Page last updated: 2024-09-04

cyc 202 and cink4

cyc 202 has been researched along with cink4 in 2 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(cink4)
Trials
(cink4)
Recent Studies (post-2010) (cink4)
97973931309

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)cink4 (IC50)
Cyclin-dependent kinase 1Homo sapiens (human)9.2
Cyclin-dependent kinase 4Homo sapiens (human)1.5
G2/mitotic-specific cyclin-B1Homo sapiens (human)9.2
G1/S-specific cyclin-D1Homo sapiens (human)1.5
G1/S-specific cyclin-E1Homo sapiens (human)5.2
Cyclin-dependent kinase 2Homo sapiens (human)5.2
Cyclin-dependent kinase 6Homo sapiens (human)5.6

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akula, N; Pattabiraman, N; Sridhar, J1
Akula, B; Athuluridivakar, S; Baker, SJ; Bharathi, EV; Billa, VK; Cosenza, SC; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR; Vasquez-Del Carpio, R1

Reviews

1 review(s) available for cyc 202 and cink4

ArticleYear
Selectivity and potency of cyclin-dependent kinase inhibitors.
    The AAPS journal, 2006, Mar-24, Volume: 8, Issue:1

    Topics: Animals; Binding Sites; Cyclin-Dependent Kinases; Humans; Protein Kinase Inhibitors; Signal Transduction

2006

Other Studies

1 other study(ies) available for cyc 202 and cink4

ArticleYear
Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).
    Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Drug Screening Assays, Antitumor; Female; Heterografts; Humans; Mice; Mice, Nude; Molecular Docking Simulation; Neoplasm Transplantation; Protein Kinases; Pyridines; Pyrimidines; Repressor Proteins; Structure-Activity Relationship

2014