Page last updated: 2024-09-04

cox 189 and dinoprostone

cox 189 has been researched along with dinoprostone in 6 studies

Compound Research Comparison

Studies
(cox 189)
Trials
(cox 189)
Recent Studies (post-2010)
(cox 189)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
163494729,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomycox 189 (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH1
Berry, C; Dawson, J; Du, Z; Esser, R; Fox, A; Fujimoto, RA; Haston, W; Kimble, EF; Koehler, J; Marshall, PJ; Peppard, J; Quadros, E; Quintavalla, J; Toscano, K; Urban, L; van Duzer, J; Zhang, X; Zhou, S1
Cramer, JA; Esser, RE; Georgieva, A; Maniara, W; Miserendino-Molteni, R; Porter, W; Ramos, L; Sharr, M; Zhang, X; Zhuang, S1
Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD1
Geisslinger, G; Manderscheid, C; Niederberger, E1
Barbieri, KP; Bosquesi, PL; Campos, ML; Chelucci, RC; Chin, CM; de Castro Souto, PC; Matsubara, MH; Moreira, V; Peccinini, RG; Santos, JL; Teixeira, C1

Other Studies

6 other study(ies) available for cox 189 and dinoprostone

ArticleYear
The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Fever; Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Intubation, Gastrointestinal; Lipopolysaccharides; Male; Organic Chemicals; Pyrazoles; Rats; Rats, Wistar; Sulfonamides

2005
Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.
    British journal of pharmacology, 2005, Volume: 144, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Availability; Blood Platelets; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Female; Fever; Fibroblasts; Humans; Hyperalgesia; Male; Membrane Proteins; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Skin; Thromboxane B2

2005
Pharmacodynamic behaviour of the selective cyclooxygenase-2 inhibitor lumiracoxib in the lipopolysaccharide-stimulated rat air pouch model.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2005, Volume: 25, Issue:1

    Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Female; Lipopolysaccharides; Organic Chemicals; Rats; Rats, Inbred Lew

2005
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2

2006
Different COX-independent effects of the COX-2 inhibitors etoricoxib and lumiracoxib.
    Biochemical and biophysical research communications, 2006, Apr-14, Volume: 342, Issue:3

    Topics: Animals; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Etoricoxib; Gene Expression Regulation; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Organic Chemicals; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Sulfones; Transcription Factor AP-1

2006
Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect.
    International journal of molecular sciences, 2012, Nov-19, Volume: 13, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Diclofenac; Dinoprostone; Disease Models, Animal; Edema; Leukocytes; Male; Mice; Molecular Structure; Peritoneal Cavity; Prodrugs; Rats; Stomach Ulcer

2012