colchicine and urea
colchicine has been researched along with urea in 39 studies
Research
Studies (39)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (51.28) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 10 (25.64) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Broom, MF; Goulding, A | 1 |
| Kimura, G; Shirai, D; Takamitsu, Y; Urakabe, S; Yuasa, S | 1 |
| Watanabe, T; Yamada, K; Yamada, M | 1 |
| Gilchrist, AJ; Juniper, BE; Robins, RJ | 1 |
| Jackson, H; Jones, P; Whiting, MH | 1 |
| Luduena, RF; MacRae, T; Mallevais, ML; Roach, MC; Trcka, PP | 1 |
| Davison, PF; Fernandez, HL; Huneeus, FC | 1 |
| Cronshaw, J; Gilder, J; Stone, D | 1 |
| McKay, RD | 1 |
| Amiel, JJ; Cattan, A; Gluckman, E; Mathé, G; Schlumberger, JR; Schneider, M; Schwarzenberg, L | 1 |
| Assimacopoulos-Jeannet, F; Jeanrenaud, B; Le Marchand, Y; Orci, L; Rouiller, C; Singh, A | 1 |
| Bhattacharyya, B; Wolff, J | 1 |
| Hemminki, K | 1 |
| Johnson, LS; Sinex, FM | 1 |
| Burton, PR | 1 |
| Barbu, E; Dandeu, JP | 1 |
| Laszlo, AH; Scotto, JM; Soifer, D | 1 |
| Chou, TC; Creasey, WA | 1 |
| von Kreybig, T | 1 |
| Ando, Y; Asano, Y; Iimura, O; Ishida, F; Kusano, E; Oono, S | 1 |
| Bhattacharyya, B; Sackett, DL; Wolff, J | 1 |
| Bhattacharyya, B; Guha, S | 1 |
| Chaudhuri, AR; Hausheer, FH; Ludueña, RF; Schwarz, PM; Seetharamalu, P | 1 |
| Chaudhuri, AR; Khan, IA; Ludueña, RF | 1 |
| BATT, RE; CIRKSENA, WJ; LEBHERZ, TB | 1 |
| C -Gaudreault, R; Côté, MF; Deschesnes, RG; Janvier, R; Lacroix, J; Legault, J; Madelmont, JC; Marquis, C; Miot-Noirault, E; Mounetou, E; Petitclerc, E | 1 |
| Feng, J; Jiang, Q; Ren, Y; Sutton, MD; Yang, F; Zhao, J | 1 |
| C-Gaudreault, R; Fortin, S; Lacroix, J; Moreau, E; Patenaude, A; Teulade, JC | 1 |
| C-Gaudreault, R; Desjardins, M; Fortin, JS; Lacroix, J; Patenaude, A; Petitclerc, E | 1 |
| C-Gaudreault, R; Fortin, S; Lacroix, J; Moreau, E; Patenaude, A; Rousseau, JL | 1 |
| C-Gaudreault, R; Fortin, S; Kotra, LP; Labrie, P; Moreau, E; Wei, L | 1 |
| Chow, SC; Tse, WK; Wong, CK | 1 |
| C-Gaudreault, R; Fortin, S; Kotra, LP; Labrie, P; Moreau, E; Petitclerc, E; Wei, L | 1 |
| C-Gaudreault, R; Côté, MF; Fortin, S; Lacroix, J; Moreau, E; Petitclerc, E | 1 |
| Boomsma, MF; Dambrink, JH; Steenmeijer, R | 1 |
| Artul, S; Badarny, S; Habib, G; Hakim, G; Khazin, F; Khreish, M; Shehadeh, V | 1 |
| Blasco, V; Carda, M; Cuñat, AC; Falomir, E; Marco, JA; Murga, J; Sanz-Cervera, JF | 1 |
| Huczyński, A; Krzywik, J; Maj, E; Mozga, W; Nasulewicz-Goldeman, A; Wietrzyk, J | 1 |
Other Studies
39 other study(ies) available for colchicine and urea
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effects of diphosphonate and colchicine administration upon acid-base changes induced in rats by bilateral nephrectomy.
Topics: Acid-Base Equilibrium; Acids; Animals; Colchicine; Etidronic Acid; Hydrogen-Ion Concentration; Hydroxyproline; Hypercalcemia; Male; Nephrectomy; Potassium; Rats; Urea; Uremia | 1979 |
Effect of colchicine on the osmotic water flow across the toad urinary bladder.
Topics: Amphotericin B; Animals; Body Water; Bufo bufo; Colchicine; Cyclic AMP; Humans; Mannitol; Osmolar Concentration; Osmotic Pressure; Urea; Urinary Bladder; Vasopressins | 1975 |
The role of subunits in tubulin. I. Renaturation of tubulin after treatment with urea and sodium dodecyl sulfate.
Topics: Animals; Brain; Cattle; Circular Dichroism; Colchicine; Glycoproteins; Kinetics; Macromolecular Substances; Protein Binding; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Tubulin; Urea | 1977 |
Some features of secretory systems in plants.
Topics: Ammonia; Asparagine; Calcium; Cell Wall; Colchicine; Cytochalasin B; Cytoplasm; Glutamine; Golgi Apparatus; Phenylalanine; Plant Cells; Plant Proteins; Plants; Urea; Uric Acid | 1977 |
Parthenogenic development after chemical treatment of Xenopus laevis spermatozoa.
Topics: Animals; Aziridines; Centrifugation; Colchicine; Female; Fertilization; Haploidy; Larva; Male; Mitosis; Ovum; Parthenogenesis; Spermatozoa; Time Factors; Urea; Xenopus | 1975 |
The effect of 2-(4-methyl-1-piperazinylmethyl) acrylophenone dihydrochloride on the alkylation of tubulin.
Topics: Alkylation; Colchicine; Fructose-Bisphosphate Aldolase; Iodoacetamide; Kinetics; Microtubules; Piperazines; Tubulin; Urea; Vincristine | 1987 |
Studies on the mechanism of axoplasmic transport in the crayfish cord.
Topics: Acetates; Astacoidea; Axonal Transport; Central Nervous System; Colchicine; Electrophoresis, Disc; Ganglia; Histocytochemistry; Histological Techniques; Injections; Leucine; Microscopy, Electron; Microtubules; Nerve Tissue Proteins; Protein Denaturation; Temperature; Tritium; Uranium; Urea | 1970 |
Fine structural studies of P-proteins in Cucurbita, Cucumis, and Nicotiana.
Topics: Colchicine; Cytoplasm; Microscopy, Electron; Models, Chemical; Nicotiana; Phosphotungstic Acid; Plant Cells; Plant Proteins; Plants, Toxic; Potassium Chloride; Sodium; Staining and Labeling; Sulfites; Urea | 1973 |
The mechanism of G and C banding in mammalian metaphase chromosomes.
Topics: Animals; Chromatin; Chromosomes; Colchicine; Evaluation Studies as Topic; Gold; Histological Techniques; L Cells; Methods; Mice; Microscopy, Phase-Contrast; Microscopy, Ultraviolet; Mitosis; Models, Biological; Palladium; Staining and Labeling; Time Factors; Urea | 1973 |
[Trial treatment of chronic myeloid leukemia with 3 new chemotherapeutic agents: dibromomannitol, hydroxyurea and desacetamidocolchicine].
Topics: Adult; Antineoplastic Agents; Colchicine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mannitol; Urea | 1966 |
A role for the microtubular system in the release of very low density lipoproteins by perfused mouse livers.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Carbon Radioisotopes; Colchicine; Gluconeogenesis; Lipoproteins, VLDL; Liver; Male; Mice; Microscopy, Electron; Microtubules; Oleic Acids; Oxygen Consumption; Perfusion; Protein Biosynthesis; Triglycerides; Urea; Vincristine | 1973 |
Promotion of fluorescence upon binding of colchicine to tubulin.
Topics: Animals; Binding Sites; Brain; Colchicine; Guanidines; Microtubules; Molecular Weight; Nerve Tissue Proteins; Podophyllotoxin; Protein Conformation; Protein Denaturation; Rats; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Temperature; Tritium; Urea; Vinblastine | 1974 |
Relative turnover of tubulin subunits in rat brain.
Topics: Animals; Blood Proteins; Cerebral Cortex; Colchicine; Electrophoresis; Kinetics; Microtubules; Peptides; Rats; Sodium Dodecyl Sulfate; Time Factors; Tritium; Urea; Vinblastine | 1973 |
On the relationship of brain filaments to microtubules.
Topics: Animals; Brain; Brain Chemistry; Centrifugation, Density Gradient; Chromatography, Thin Layer; Colchicine; Densitometry; Detergents; Drug Stability; Electrophoresis, Disc; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Female; Hydrogen-Ion Concentration; Microscopy, Electron; Microtubules; Molecular Weight; Nerve Tissue Proteins; Neuroglia; Optic Nerve; Peptide Fragments; Protein Conformation; Rats; Solubility; Temperature; Urea | 1974 |
Effects of various treatments on microtubules and axial units of lung-fluke spermatozoa.
Topics: Animals; Anura; Colchicine; Cold Temperature; Male; Mercaptoethanol; Organoids; Pepsin A; Potassium Chloride; Spermatozoa; Trematoda; Urea | 1968 |
[Purification of colchicine K].
Topics: Acetates; Chemical Phenomena; Chemistry; Colchicine; Dextrans; Electrophoresis; Guanidines; Mercaptoethanol; Molecular Weight; Urea | 1967 |
Enzymatic activity in tubulin preparations. I. Intrinsic protein kinase activity in lyophilized preparations of tubulin from porcine brain.
Topics: Adenosine Triphosphate; Animals; Brain; Caseins; Colchicine; Electrophoresis; Fluorides; Guanosine Triphosphate; Histones; Hydrogen-Ion Concentration; Kinetics; Microtubules; Nerve Tissue Proteins; Phosphorus Isotopes; Phosphotransferases; Sodium Dodecyl Sulfate; Swine; Urea; Vinblastine | 1972 |
The binding of colchicine by sarcoma 180 cells.
Topics: Animals; Ascitic Fluid; Centrifugation; Chromatography, Gel; Colchicine; Culture Techniques; Dialysis; Mice; Neoplasm Proteins; Protein Binding; Sarcoma 180; Serum Albumin, Bovine; Tritium; Urea | 1968 |
[Experimental animal teratology and drug tests].
Topics: Abnormalities, Drug-Induced; Amides; Animals; Brain; Colchicine; Cyclophosphamide; Female; Limb Deformities, Congenital; Mice; Nitroso Compounds; Pregnancy; Rats; Skull; Solvents; Urea; Urethane | 1966 |
Hyperosmolality rapidly reduces atrial-natriuretic-peptide-dependent cyclic guanosine monophosphate production in cultured rat inner medullary collecting duct cells.
Topics: Alkaloids; Animals; Atrial Natriuretic Factor; Cells, Cultured; Colchicine; Cyclic GMP; Cytochalasin B; Enzyme Inhibitors; Kidney Medulla; Kidney Tubules, Collecting; Male; Mannitol; Naphthalenes; Osmolar Concentration; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Sodium Chloride; Staurosporine; Urea | 1995 |
Local unfolding and the stepwise loss of the functional properties of tubulin.
Topics: Anilino Naphthalenesulfonates; Animals; Brain Chemistry; Chymotrypsin; Colchicine; Fluorescent Dyes; GTP Phosphohydrolases; Kinetics; Microtubules; Polymers; Protein Folding; Rats; Spectrometry, Fluorescence; Tropolone; Trypsin; Tryptophan; Tubulin; Urea | 1994 |
Refolding of urea-denatured tubulin: recovery of nativelike structure and colchicine binding activity from partly unfolded states.
Topics: 2-Naphthylamine; Animals; Circular Dichroism; Colchicine; Dimerization; Goats; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tubulin; Urea | 1997 |
The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach.
Topics: Amino Acid Sequence; Animals; Bibenzyls; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Colchicine; Fluorescence; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Podophyllotoxin; Protein Conformation; Protein Footprinting; Stilbenes; Tropolone; Tryptophan; Tubulin; Urea | 2000 |
Detection of disulfide bonds in bovine brain tubulin and their role in protein folding and microtubule assembly in vitro: a novel disulfide detection approach.
Topics: Ammonium Sulfate; Animals; Brain Chemistry; Cattle; Colchicine; Cysteine; Disulfides; Dithiothreitol; Microtubules; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Reducing Agents; Spectrometry, Fluorescence; Tryptophan; Tubulin; Urea | 2001 |
GOUT AND SALT-WASTING RENAL DISEASE DURING PREGNANCY; DIAGNOSIS, MANAGEMENT, AND FOLLOW-UP.
Topics: Blood Chemical Analysis; Colchicine; Diet Therapy; Diet, Sodium-Restricted; Female; Follow-Up Studies; Gout; Humans; Hyponatremia; Kidney Diseases; Labor, Induced; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Probenecid; Puerperal Disorders; Pyelonephritis; Urea; Uremia | 1963 |
Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: a class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance.
Topics: Actins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Cell Division; Cell Line, Tumor; Cells, Cultured; Chick Embryo; Colchicine; Colonic Neoplasms; Cricetinae; Cytoskeleton; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Endothelium, Vascular; Extracellular Matrix; Humans; Mice; Mice, Inbred BALB C; Microtubules; Paclitaxel; Tubulin; Urea | 2004 |
Parkin stabilizes microtubules through strong binding mediated by three independent domains.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Line; Chromatography; Colchicine; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Microscopy, Fluorescence; Microtubules; Models, Biological; Mutation; Paclitaxel; Protein Binding; Protein Folding; Protein Structure, Tertiary; Salts; Transfection; Tubulin; Ubiquitin-Protein Ligases; Urea | 2005 |
N-Phenyl-N'-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N'-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety?
Topics: Antimitotic Agents; Binding, Competitive; Cell Cycle; Cell Line, Tumor; Chemistry, Pharmaceutical; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Stilbenes; Tubulin; Urea | 2007 |
Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site.
Topics: Antineoplastic Agents, Alkylating; Binding Sites; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; HT29 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Protein Binding; Proteins; Structure-Activity Relationship; Substrate Specificity; Tubulin; Urea | 2007 |
N-Phenyl-N'-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. Part 3: role of carbonyl groups in the covalent binding to the colchicine-binding site.
Topics: Alkylation; Antineoplastic Agents; Binding Sites; Carbonic Acid; Cell Line, Tumor; Cell Proliferation; Chlorine Compounds; Colchicine; DNA; Humans; Molecular Structure; Structure-Activity Relationship; Tubulin; Urea | 2008 |
A comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N'-(2-chloroethyl)ureas targeting the colchicine-binding site as anticancer agents.
Topics: Antimitotic Agents; Binding Sites; Colchicine; Drug Design; Humans; Models, Molecular; Quantitative Structure-Activity Relationship; Tubulin; Tubulin Modulators; Urea | 2008 |
The cloning of eel osmotic stress transcription factor and the regulation of its expression in primary gill cell culture.
Topics: Amino Acid Sequence; Animals; Base Sequence; Betaine; Cells, Cultured; Cloning, Molecular; Colchicine; DNA Primers; Eels; Gene Expression Regulation; Gills; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology; Sodium Chloride; Species Specificity; Transcription Factors; Urea; Water-Electrolyte Balance | 2008 |
Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin.
Topics: Binding Sites; Cell Line, Tumor; Colchicine; Computer Simulation; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Urea | 2009 |
Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N'-(2-chloroethyl)ureas.
Topics: Amides; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colchicine; Humans; Structure-Activity Relationship; Tubulin; Urea | 2010 |
[A young man with recurrent chest pain].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Colchicine; Diagnosis, Differential; Humans; Male; Pericarditis; Secondary Prevention; Urea; Young Adult | 2012 |
The impact of Ramadan fast on patients with gout.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Body Mass Index; Case-Control Studies; Colchicine; Creatinine; Fasting; Female; Gout; Gout Suppressants; Humans; Islam; Israel; Male; Middle Aged; Patient Compliance; Urea; Uric Acid | 2014 |
Arylureas derived from colchicine: Enhancement of colchicine oncogene downregulation activity.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colchicine; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Molecular Structure; Proto-Oncogene Proteins c-myc; Structure-Activity Relationship; Telomerase; Urea; Vascular Endothelial Growth Factor Receptor-2 | 2018 |
Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Guanidine; Humans; Molecular Structure; Structure-Activity Relationship; Thiourea; Urea | 2021 |