clonidine has been researched along with st 91 in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (29.69) | 18.7374 |
| 1990's | 29 (45.31) | 18.2507 |
| 2000's | 11 (17.19) | 29.6817 |
| 2010's | 5 (7.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leclerc, G; Rouot, B; Wermuth, CG | 1 |
| Kim, KH; Martin, YC | 1 |
| Good, AC; Peterson, SJ; Richards, WG | 1 |
| Kobinger, W; Pichler, L | 1 |
| Bohidar, NR; Ludden, CT; Scriabine, A; Stavorski, JM; Sweet, CS; Wenger, HC | 1 |
| Saeki, S; Yaksh, TL | 1 |
| Browne, BJ; Condon, RE; Cowles, VE; Salaymeh, BM; Tekin, E; Zhu, YR | 1 |
| Takano, M; Takano, Y; Yaksh, TL | 1 |
| Jones, SL | 1 |
| Eisenach, JC; Tong, CY | 1 |
| Boublik, JH; Brown, MR; Hua, XY; Rivier, JE; Spicer, MA; Yaksh, TL | 1 |
| Takano, Y; Yaksh, TL | 2 |
| Chatterjee, P; Chestnut, DH; Sipes, SL; Thompson, CS; Vincent, RD; Weiner, CP | 1 |
| Barney, CC; Katovich, MJ; Pitman, DL | 1 |
| Monasky, MS; Stevens, CW; Yaksh, TL; Zinsmeister, AR | 1 |
| Camilleri, M; Malagelada, JR; Thomforde, GM; Yaksh, TL | 1 |
| Stevens, CW; Yaksh, TL | 1 |
| Widdop, RE | 1 |
| Boulis, NM; Cassella, JV; Commissaris, RL; Davis, M; Kehne, JH; Wagner, KR; Yang, S | 1 |
| Verosky, M; Vulliemoz, Y | 1 |
| Monasky, MS; Stevens, CW; Yaksh, TL | 1 |
| Appia, F; Chariot, J; del Tacca, M; Rozé, C; Tsocas, A | 1 |
| Aghajanian, GK; Cassella, JV; Davis, M; Kehne, JH; Tallman, JF | 1 |
| Martin, DL; Suzuki, M; Valentino, RJ | 1 |
| Kast, A; Muacevic, G | 1 |
| Reddy, SV; Yaksh, TL | 1 |
| Genton, M; Pascaud, X; Roger, A; Rozé, C | 1 |
| Howe, JR; Wang, JY; Yaksh, TL | 1 |
| Yaksh, TL; Yasuoka, S | 1 |
| Gebhart, GF; Ossipov, MH | 1 |
| Jarrott, B; Louis, WJ; Summers, RJ | 1 |
| Bentley, GA; McLennan, PL | 1 |
| Anton, F; Dubner, R; Kenshalo, DR; Thomas, DA; Williams, GM | 1 |
| Fendt, M; Koch, M; Schnitzler, HU | 1 |
| Luo, L; Puke, MJ; Xu, XJ | 1 |
| Detweiler, DJ; Eisenach, JC; Jackson, C; Tong, C | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Dowlatshahi, P; Yaksh, TL | 1 |
| Gutkowska, J; Mukaddam-Daher, S; Tremblay, J | 1 |
| Dunbar, SA; Yaksh, TL | 1 |
| Gutkowska, J; Lambert, C; Mukaddam-Daher, S | 1 |
| Graham, BA; Hammond, DL; Proudfit, HK | 2 |
| Benedek, G; Dobos, I; Horváth, G; Klimscha, W; Liszli, P; Szikszay, M | 1 |
| Black, WD; Celly, CS; McDonell, WN; Young, SS | 1 |
| Elsworth, JD; Punch, LJ; Taylor, JR | 1 |
| Atwal, OS; Black, WD; Celly, CS; McDonell, WN | 1 |
| Black, WD; Celly, CS; McDonell, WN | 1 |
| Delfs, J; Highfield, D; Leung, S; Shaham, Y; Stewart, J | 1 |
| Aston-Jones, G; Delfs, JM; Druhan, JP; Zhu, Y | 1 |
| Alila-Johansson, A; Hätönen, T; Laakso, M; Mustanoja, SM | 1 |
| Bantel, C; Duflo, F; Eisenach, JC; Li, X; Pancaro, C; Vincler, M | 1 |
| Conklin, D; Duflo, F; Eisenach, JC; Li, X | 1 |
| Andicochea, CT; Krall, CM; McDougall, SA | 1 |
| Eisenach, JC; Fairbanks, CA; Kitto, KF; Stone, LS; Wilcox, GL | 1 |
| Gyires, K; Kató, E; Lipták, L; Mátyus, P; Rónai, AZ; Shujaa, N | 1 |
| Christianson, CA; Hua, XY; Nazarian, A; Yaksh, TL | 1 |
| Al-Khrasani, M; Gyires, K; Mátyus, P; Mózes, MM; Pap, B; Shujaa, N; Zádori, ZS | 1 |
| Cowan, A; Hirsch, DD; Kim, J; Lisek, R; Rawls, SM; Raymondi, N; Rosenthal, A | 1 |
| Al-Khrasani, M; Gyires, K; Hein, L; Mátyus, P; Németh, J; Rossi, M; Shujaa, N; Zádori, ZS | 1 |
| Brancati, SB; Gyires, K; Hein, L; Shujaa, N; Zádori, ZS | 1 |
| Jun, JH; Kim, HJ; Lee, HJ; Seol, TK; Yaksh, TL | 1 |
| Endo, S; Kozawa, M; Murakami, H; Muto, M; Tadano, T; Tan-No, K; Tsuchiya, M; Yaoita, F | 1 |
1 trial(s) available for clonidine and st 91
| Article | Year |
|---|---|
A cholinergic interaction in alpha 2 adrenoceptor-mediated antinociception in sheep.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Dioxanes; Female; Humans; Idazoxan; Imidazoles; Injections, Spinal; Medetomidine; Receptors, Cholinergic; Sheep | 1993 |
63 other study(ies) available for clonidine and st 91
| Article | Year |
|---|---|
Clonidine and related analogues. Quantitative correlations.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Chemical Phenomena; Chemistry, Physical; Clonidine; Imidazoles; Mathematics; Rats; Structure-Activity Relationship | 1976 |
Direct prediction of dissociation constants (pKa's) of clonidine-like imidazolines, 2-substituted imidazoles, and 1-methyl-2-substituted-imidazoles from 3D structures using a comparative molecular field analysis (CoMFA) approach.
Topics: Clonidine; Imidazoles; Kinetics; Models, Chemical; Stereoisomerism; Structure-Activity Relationship | 1991 |
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship | 1993 |
Investigation into some imidazoline compounds, with respect to peripheral alpha-adrenoceptor stimulation and depression of cardiovascular centers.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Dogs; Female; Heart Rate; Imidazoles; Imidazolidines; Male; Naphazoline; Oxymetazoline; Pressoreceptors; Rats; Receptors, Adrenergic; Reflex; Vagotomy; Vagus Nerve; Vasomotor System; Xylazine | 1975 |
Some cardiovascular effects of ST-91 and clonidine.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Desipramine; Dogs; Electric Stimulation; Female; Heart Rate; Hemodynamics; Hypertension; Imidazoles; Injections, Intraventricular; Male; Phenoxybenzamine; Phentolamine; Rats; Time Factors; Vagotomy | 1977 |
Suppression by spinal alpha-2 agonists of motor and autonomic responses evoked by low- and high-intensity thermal stimuli.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Heart Rate; Hot Temperature; Imidazoles; Male; Medetomidine; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic, alpha; Reflex | 1992 |
Selective adrenergic agonists and colon motility in monkeys.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Clonidine; Colon; Dobutamine; Dose-Response Relationship, Drug; Gastrointestinal Motility; Macaca fascicularis; Phenylephrine; Terbutaline | 1992 |
The effect of intrathecally administered imiloxan and WB4101: possible role of alpha 2-adrenoceptor subtypes in the spinal cord.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; Injections, Spinal; Male; Medetomidine; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord | 1992 |
Noradrenergic modulation of noxious heat-evoked fos-like immunoreactivity in the dorsal horn of the rat sacral spinal cord.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Immunohistochemistry; Injections, Spinal; Iontophoresis; Male; Neurons, Afferent; Nociceptors; Norepinephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord | 1992 |
Site of hemodynamic effects of intrathecal alpha 2-adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Hemodynamics; Idazoxan; Injections, Spinal; Sheep | 1991 |
The antinociceptive effects of spinally administered neuropeptide Y in the rat: systematic studies on structure-activity relationship.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Injections, Spinal; Male; Motor Activity; Naloxone; Neuropeptide Y; Pain; Parasympathomimetics; Peptide Fragments; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1991 |
Relative efficacy of spinal alpha-2 agonists, dexmedetomidine, clonidine and ST-91, determined in vivo by using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Injections, Spinal; Male; Medetomidine; Morphine; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord | 1991 |
Does magnesium sulfate alter the maternal cardiovascular response to vasopressor agents in gravid ewes?
Topics: Angiotensin II; Animals; Arginine Vasopressin; Clonidine; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Magnesium Sulfate; Phenylephrine; Pregnancy; Regional Blood Flow; Sheep; Uterus; Vascular Resistance | 1991 |
Mechanisms mediating the thermal response to morphine withdrawal in rats.
Topics: Adrenal Glands; Adrenergic alpha-Agonists; Animals; Body Temperature; Clonidine; Female; Morphine; Naloxone; Propranolol; Rats; Receptors, Adrenergic; Skin Temperature; Substance Withdrawal Syndrome | 1990 |
Interaction of intrathecal morphine and ST-91 on antinociception in the rat: dose-response analysis, antagonism and clearance.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Injections, Spinal; Male; Morphine; Naloxone; Pain; Parasympathomimetics; Phentolamine; Rats; Rats, Inbred Strains; Reaction Time; Regression Analysis | 1990 |
Demonstration of intrathecal and systemic morphine and ST-91 effects on fed canine upper gut motility.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Drug Interactions; Eating; Gastrointestinal Motility; Injections, Intravenous; Injections, Spinal; Morphine; Naloxone; Phentolamine; Propranolol | 1990 |
Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
Topics: Analgesics; Animals; Clonidine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Infusions, Parenteral; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Reference Values; Sufentanil | 1989 |
The effects of B-HT 920 and St 91 on venous haemodynamics in cats.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Cats; Clonidine; Female; Hemodynamics; Male | 1989 |
Spinal vs. supraspinal sites of action of the alpha 2-adrenergic agonists clonidine and ST-91 on the acoustic startle reflex.
Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Clonidine; Cochlea; Electric Stimulation; Electrodes, Implanted; Injections, Intraventricular; Injections, Spinal; Rats; Rats, Inbred Strains; Reflex, Startle; Spinal Cord | 1989 |
Effect of clonidine on myocardial cyclic GMP content in the mouse-activation of central and peripheral alpha adrenoceptors.
Topics: Animals; Brain; Clonidine; Cyclic GMP; Hexamethonium; Hexamethonium Compounds; Male; Mice; Myocardium; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1989 |
Spinal infusion of opiate and alpha-2 agonists in rats: tolerance and cross-tolerance studies.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Spinal; Male; Morphine; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Central and peripheral inhibition of exocrine pancreatic secretion by alpha-2 adrenergic agonists in the rat.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Clonidine; Male; Pancreas; Prazosin; Rats; Rats, Inbred Strains | 1988 |
Pertussis toxin or 8-bromo-cAMP block inhibition of the acoustic startle response by the alpha 2-adrenergic agonist ST-91.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Clonidine; Cyclic AMP; Injections, Intraventricular; Male; Pertussis Toxin; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex, Startle; Virulence Factors, Bordetella | 1987 |
Dissociation of locus coeruleus activity and blood pressure. Effects of clonidine and corticotropin-releasing factor.
Topics: Animals; Blood Pressure; Cerebral Ventricles; Clonidine; Corticotropin-Releasing Hormone; Injections, Intravenous; Injections, Intraventricular; Locus Coeruleus; Male; Rats; Rats, Inbred Strains | 1986 |
Reversible pulmonary changes in rats dosed intravenously with imidazoles.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Female; Hemorrhage; Hemosiderosis; Imidazoles; Injections, Intravenous; Lethal Dose 50; Lung; Lung Diseases; Male; Organ Size; Pulmonary Edema; Rats; Rats, Inbred Strains | 1986 |
Studies in the primate on the analgetic effects associated with intrathecal actions of opiates, alpha-adrenergic agonists and baclofen.
Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Avoidance Learning; Baclofen; Behavior, Animal; Cats; Clonidine; Drug Interactions; Electroshock; Female; Injections, Spinal; Macaca; Macaca mulatta; Male; Meperidine; Morphine; Naloxone; Narcotics; Pain; Phentolamine; Sensory Thresholds; Spinal Cord | 1981 |
Further support for the central origin of the gastric antisecretory properties of clonidine in conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Deoxyglucose; Depression, Chemical; Drug Interactions; Gastric Mucosa; Histamine; Male; Methacholine Chloride; Methacholine Compounds; Pentagastrin; Rats; Rats, Inbred Strains | 1982 |
Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Hot Temperature; Hydroxydopamines; Injections, Spinal; Male; Methoxamine; Norepinephrine; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1983 |
Effects on nociceptive threshold and blood pressure of intrathecally administered morphine and alpha-adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Injections, Spinal; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Species Specificity; Time Factors | 1983 |
Absence of antinociceptive effect of alpha-2 agonists microinjected in the periaqueductal gray of the rat.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Isoproterenol; Male; Morphine; Nociceptors; Periaqueductal Gray; Phenylephrine; Rats; Rats, Inbred Strains; Synaptic Transmission; Tolazoline | 1983 |
Selectivity of a series of clonidine-like drugs for alpha 1 and alpha 2 adrenoceptors in rat brain.
Topics: Aniline Compounds; Animals; Cerebral Cortex; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; In Vitro Techniques; Indoramin; Naphazoline; Oxazoles; Phenylacetates; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Thiophenes; Toluidines | 1980 |
Effects of prazosin and piperoxan on central cardiovascular actions of St 91 in cats.
Topics: Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Male; Piperidines; Piperoxan; Prazosin; Quinazolines; Vertebral Artery | 1982 |
Noradrenergic and opioid systems interact to alter the detection of noxious thermal stimuli and facial scratching in monkeys.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Antagonists; Animals; Behavior, Animal; Clonidine; Dioxanes; Electrophysiology; Hot Temperature; Idazoxan; Macaca fascicularis; Macaca mulatta; Male; Medulla Oblongata; Microinjections; Naloxone; Norepinephrine; Pain; Physical Stimulation; Receptors, Opioid | 1993 |
Amygdaloid noradrenaline is involved in the sensitization of the acoustic startle response in rats.
Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Amygdala; Animals; Clonidine; Dose-Response Relationship, Drug; Electroshock; Injections; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex, Startle; Yohimbine | 1994 |
The spinal analgesic role of alpha 2-adrenoceptor subtypes in rats after peripheral nerve section.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Animals; Behavior, Animal; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electrophysiology; Guanfacine; Injections, Spinal; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Sciatic Nerve | 1994 |
Chronic spinal infusion of dexmedetomidine, ST-91 and clonidine: spinal alpha 2 adrenoceptor subtypes and intrinsic activity.
Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Catheterization; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Imidazoles; Infusion Pumps, Implantable; Injections, Spinal; Medetomidine; Molecular Sequence Data; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Time Factors | 1993 |
Pharmacology of the spinal action of ketorolac, morphine, ST-91, U50488H, and L-PIA on the formalin test and an isobolographic analysis of the NSAID interaction.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Combinations; Drug Interactions; Formaldehyde; Ketorolac; Male; Morphine; Motor Activity; Nociceptors; Phenylisopropyladenosine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tolmetin | 1993 |
Differential effects of two intraventricularly injected alpha 2 agonists, ST-91 and dexmedetomidine, on electroencephalogram, feeding, and electromyogram.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Conscious Sedation; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Feeding Behavior; Imidazoles; Injections, Intraventricular; Male; Medetomidine; Methoxamine; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
The peripheral action of clonidine analog ST-91: involvement of atrial natriuretic factor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Clonidine; Cyclic GMP; Female; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium | 1997 |
Spinal infusion of N-methyl-D-aspartate antagonist MK801 induces hypersensitivity to the spinal alpha-2 agonist ST91 in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Hypersensitivity; Injections, Spinal; Male; Pain; Rats; Rats, Sprague-Dawley; Reaction Time | 1997 |
Clonidine and ST-91 may activate imidazoline binding sites in the heart to release atrial natriuretic peptide.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Binding Sites; Chromatography, High Pressure Liquid; Clonidine; Female; Heart Atria; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Drug; Time Factors | 1997 |
Differences in the antinociceptive effects of alpha-2 adrenoceptor agonists in two substrains of Sprague-Dawley rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Injections, Spinal; Male; Medetomidine; Rats; Rats, Sprague-Dawley; Species Specificity; Spinal Cord | 1997 |
Antinociceptive effects of the hydrophilic alpha 2-adrenoceptor agonist ST-91 in different test circumstances after intrathecal administration to Wistar rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Injections, Spinal; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1997 |
Cardiopulmonary effects of clonidine, diazepam and the peripheral alpha 2 adrenoceptor agonist ST-91 in conscious sheep.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Animals; Clonidine; Diazepam; Female; Hemodynamics; Hypoxia; Pulmonary Gas Exchange; Respiration; Sheep | 1997 |
A comparison of the effects of clonidine and CNQX infusion into the locus coeruleus and the amygdala on naloxone-precipitated opiate withdrawal in the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Amygdala; Animals; Clonidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Locus Coeruleus; Male; Morphine Dependence; N-Methylaspartate; Naloxone; Narcotic Antagonists; Norepinephrine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1998 |
Histopathologic alterations induced in the lungs of sheep by use of alpha2-adrenergic receptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Female; Hypnotics and Sedatives; Lung; Lung Diseases; Macrophages; Microscopy, Electron; Sheep; Sheep Diseases; Xylazine | 1999 |
Cardiopulmonary effects of the alpha2-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Anesthesia; Animals; Carbon Dioxide; Clonidine; Dose-Response Relationship, Drug; Female; Hemodynamics; Imidazoles; Medetomidine; Oxygen Consumption; Respiratory Mechanics; Sheep | 1999 |
Clonidine blocks stress-induced reinstatement of heroin seeking in rats: an effect independent of locus coeruleus noradrenergic neurons.
Topics: Animals; Cerebral Ventricles; Clonidine; Electroshock; Extinction, Psychological; Heroin; Heroin Dependence; Injections, Intraventricular; Locus Coeruleus; Male; Medial Forebrain Bundle; Neurons; Norepinephrine; Oxidopamine; Parasympathomimetics; Rats; Rats, Long-Evans; Self Administration; Stress, Psychological | 2000 |
Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Amygdala; Animals; Betaxolol; Clonidine; Male; Narcotics; Neurons, Afferent; Norepinephrine; Propanolamines; Propranolol; Prosencephalon; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 2000 |
Synergistic interactions between two alpha(2)-adrenoceptor agonists, dexmedetomidine and ST-91, in two substrains of Sprague-Dawley rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Male; Motor Activity; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Species Specificity | 2000 |
Evidence for central alpha(2)-adrenergic modulation of rat pineal melatonin synthesis.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Circadian Rhythm; Clonidine; Male; Medetomidine; Melatonin; Pineal Gland; Quinolizines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2000 |
Peripheral nerve injury alters the alpha2 adrenoceptor subtype activated by clonidine for analgesia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Injections, Spinal; Male; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 2002 |
Spinal adrenergic and cholinergic receptor interactions activated by clonidine in postincisional pain.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Injections, Spinal; Male; Pain, Postoperative; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Spinal Cord; Time Factors | 2003 |
Ultrasonic vocalization production of preweanling rats: effects of central and peripheral administration of alpha2-adrenoceptor agonists.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Rats; Rats, Sprague-Dawley; Ultrasonics; Vocalization, Animal; Yohimbine | 2005 |
ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Back Pain; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Mice; Point Mutation; Receptors, Adrenergic, alpha-2; Spinal Cord; Substance P | 2007 |
alpha2B-adrenoceptor agonist ST-91 antagonizes beta2-adrenoceptor-mediated relaxation in rat mesenteric artery rings.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Terbutaline; Vas Deferens; Vasodilation; Xylazine; Yohimbine | 2008 |
Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gene Expression Regulation; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Neurokinin-1; Substance P | 2008 |
Pharmacological analysis of alpha(2)-adrenoceptor subtypes mediating analgesic, anti-inflammatory and gastroprotective actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Clonidine; Disease Models, Animal; Edema; Gastrointestinal Motility; Hyperalgesia; Male; Oxazoles; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rilmenidine; Stomach Ulcer | 2009 |
Icilin-evoked behavioral stimulation is attenuated by alpha₂-adrenoceptor activation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Head Movements; Male; Movement Disorders; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2011 |
α(2)-adrenoceptor agonist-induced inhibition of gastric motor activity is mediated by α(2A)-adrenoceptor subtype in the mouse.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Adrenergic, alpha-2; Stomach | 2011 |
Both α2B- and α2C-adrenoceptor subtypes are involved in the mediation of centrally induced gastroprotection in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Ethanol; Female; Male; Mice; Mice, Knockout; Protective Agents; Receptors, Adrenergic, alpha-2; Stomach Ulcer | 2011 |
The effect of intrathecal mu, delta, kappa, and alpha-2 agonists on thermal hyperalgesia induced by mild burn on hind paw in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-2 Receptor Agonists; Animals; Burns; Clonidine; Enkephalin, D-Penicillamine (2,5)-; Hyperalgesia; Male; Morphine; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 2011 |
Involvement of peripheral alpha2A adrenoceptor in the acceleration of gastrointestinal transit and abdominal visceral pain induced by intermittent deprivation of REM sleep.
Topics: Acetic Acid; Acridines; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileum; Imidazoles; Irritable Bowel Syndrome; Isoindoles; Male; Mice; Piperazines; Receptors, Adrenergic; Sleep Deprivation; Sleep, REM; Visceral Pain | 2018 |