cimetidine and gamma-aminobutyric acid

cimetidine has been researched along with gamma-aminobutyric acid in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's1 (5.00)18.2507
2000's5 (25.00)29.6817
2010's9 (45.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S1
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E1
Bhowmick, S; Bose, R; Pal, M; Pal, SP1
Callaway, JC; Stuart, AE1
Guidobono, F; Netti, C; Pagani, F; Pecile, A; Sibilia, V1
Cole, S; Trzeciakowski, JP1
Aghajanian, GK; Lakoski, JM1
Aghajanian, GK; Gallager, DW; Lakoski, JM1
Hough, LB; Leurs, R; Menge, WM; Nalwalk, JW; Timmerman, H1
Kounenis, G; Koutsoviti-Papadopoulou, M; Nikolaidis, E1
Blumenthal, R; Cundy, KC; Ho, J; Lal, R; Luo, W; Sukbuntherng, J; Vicente, V1
Heinricher, MM; Hough, LB; Lee, D; Maire, JJ; Nalwalk, JW1
Baviera, AM; Benzi, JRL; de Moraes, NV; Stevens, JH; Yamamoto, PA1

Other Studies

20 other study(ies) available for cimetidine and gamma-aminobutyric acid

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2008
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship

2013
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
    Bioorganic & medicinal chemistry, 2013, May-15, Volume: 21, Issue:10

    Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship

2013
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
    Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

2017
Antiulcer activity of N-phthaloyl GABA--a new GABA mimetic agent.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:2

    Topics: 3-Mercaptopropionic Acid; Animals; Anti-Ulcer Agents; Bicuculline; Cimetidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Rats; Stomach Ulcer; Valproic Acid

1990
Comparison of the responses to light and to GABA of cells postsynaptic to barnacle photoreceptors (I-cells).
    Visual neuroscience, 1989, Volume: 3, Issue:4

    Topics: Animals; Bicuculline; Cations, Divalent; Cimetidine; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guanidines; Light; Osmolar Concentration; Photoreceptor Cells; Picrotoxin; Propionates; Synapses; Thoracica

1989
Cimetidine-induced prolactin release: possible involvement of the GABA-ergic system.
    Neuroendocrinology, 1985, Volume: 40, Issue:3

    Topics: Animals; Cimetidine; Diazepam; gamma-Aminobutyric Acid; Imidazoles; Impromidine; Male; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Synaptic Transmission

1985
Ranitidine potentiates ileum contractions caused by GABA and electrical stimulation.
    Life sciences, 1986, Jan-13, Volume: 38, Issue:2

    Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Parasympathetic Nervous System; Physostigmine; Ranitidine; Receptors, GABA-A

1986
Effects of histamine, H1- and H2-receptor antagonists on the activity of serotonergic neurons in the dorsal raphe nucleus.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Animals; Brain Stem; Cimetidine; Diphenhydramine; gamma-Aminobutyric Acid; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Metiamide; Neurons; Pyrilamine; Ranitidine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin; Synaptic Transmission

1983
Histamine-induced depression of serotoninergic dorsal raphe neurons: antagonism by cimetidine, a reevaluation.
    European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2

    Topics: Animals; Cimetidine; gamma-Aminobutyric Acid; Histamine; Histamine H2 Antagonists; Iontophoresis; Male; Muscimol; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin

1984
Significance of GABAergic systems in the action of improgan, a non-opioid analgesic.
    Life sciences, 2001, May-04, Volume: 68, Issue:24

    Topics: Analgesics, Non-Narcotic; Animals; Cimetidine; gamma-Aminobutyric Acid; Male; Morphine; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2001
Enhancing and inhibitory effects of H2-receptor antagonists on the GABA and the GABAA-agonist muscimol responses of the isolated guinea pig ileum: a pharmacodynamic interaction.
    Pharmacological research, 2003, Volume: 48, Issue:3

    Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Famotidine; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine H2 Antagonists; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Receptors, GABA; Receptors, GABA-A

2003
Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine.
    British journal of clinical pharmacology, 2010, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Biological Transport; Carbamates; Cimetidine; Constipation; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Dyspepsia; Fatigue; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Naproxen; Prodrugs; Young Adult

2010
Physiological basis for inhibition of morphine and improgan antinociception by CC12, a P450 epoxygenase inhibitor.
    Journal of neurophysiology, 2010, Volume: 104, Issue:6

    Topics: Action Potentials; Analgesics; Animals; Cimetidine; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Imidazoles; Male; Medulla Oblongata; Models, Neurological; Morphine; Pain Perception; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; Receptors, Presynaptic; Signal Transduction; Sulfides

2010
The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats.
    Life sciences, 2018, May-01, Volume: 200

    Topics: Amines; Animals; Cimetidine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Male; Metformin; Organic Cation Transporter 2; Rats; Rats, Wistar

2018
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