Page last updated: 2024-09-05

bms204352 and lopinavir

bms204352 has been researched along with lopinavir in 2 studies

Compound Research Comparison

Studies
(bms204352)
Trials
(bms204352)
Recent Studies (post-2010)
(bms204352)
Studies
(lopinavir)
Trials
(lopinavir)
Recent Studies (post-2010) (lopinavir)
491122,3834991,358

Protein Interaction Comparison

ProteinTaxonomybms204352 (IC50)lopinavir (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)1.7
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 29.12
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.035
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)8.5114
Protease Human immunodeficiency virus 10.025
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.6
Protease Human immunodeficiency virus 10.0175

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

2 other study(ies) available for bms204352 and lopinavir

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
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