biotin has been researched along with warfarin in 25 studies
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (warfarin) | Trials (warfarin) | Recent Studies (post-2010) (warfarin) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 36,573 | 2,143 | 14,728 |
| Protein | Taxonomy | biotin (IC50) | warfarin (IC50) |
|---|---|---|---|
| Vitamin K epoxide reductase complex subunit 1 | Homo sapiens (human) | 0.0088 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 14 (56.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Suttie, JW | 1 |
| Coustal, S; Desbene, PL; Frappier, F | 1 |
| Raap, AK; Tanke, HJ; van de Corput, MP; van Gijlswijk, RP; Vervenne, RA; Wiegant, J | 1 |
| Halton, DW; McGinty, A; Moore, M; Walker, B | 1 |
| Endres, M; Fink, K; Moskowitz, MA; Namura, S; Srinivasan, A; Tomaselli, KJ; Yuan, J; Zhu, J | 1 |
| Adamczyk, M; Fishpaugh, JR; Mattingly, PG | 1 |
| Fürmann, C; Häcker, G; Mack, A | 1 |
| Ashizuka, Y; Hashimoto, K; Hohsaka, T; Murakami, H; Sisido, M | 1 |
| Burkart, MD; Mercer, AC | 1 |
| Giroux, A; Grimm, E; Han, Y; Nicholson, DW; Tawa, P; Xanthoudakis, S | 1 |
| Eikelboom, JW; Weitz, JI | 1 |
| Büller, HR; Gallus, AS; Pillion, G; Prins, MH; Raskob, GE | 1 |
| Bhuniya, S; Han, JH; Jeon, HM; Kang, C; Kim, JS; Lee, JH; Maiti, S; Park, N | 1 |
| Chung, SJ; Kang, HJ; Kim, JH; Sumranjit, J | 1 |
| Jung, D; Kim, JS; Lee, JH; Maiti, S | 1 |
| Buller, HR; Halperin, J; Hankey, GJ; Pillion, G; Prins, MH; Raskob, GE | 1 |
| Greaves, M | 1 |
| Reitsma, PH; Rosendaal, FR | 1 |
| Duan, L; Qian, J; Sun, Q; Tian, H; Zhang, W | 1 |
| Löser, R; Pietsch, M; Pietzsch, J; Schramm, G; Wodtke, R | 1 |
| Amin, MA; Bhattacharyya, K; Chowdhury, R; Ghosh, S; Mondal, P; Nandi, S | 1 |
1 review(s) available for biotin and warfarin
| Article | Year |
|---|---|
Mechanism of action of vitamin K: synthesis of gamma-carboxyglutamic acid.
Topics: 1-Carboxyglutamic Acid; Adenosine Triphosphate; Animals; Biotin; Carbon Dioxide; Carbon-Carbon Ligases; Coumarins; Glutamates; Humans; Ligases; Mixed Function Oxygenases; Molecular Conformation; Oxygen; Prothrombin; Substrate Specificity; Vitamin K; Vitamin K Epoxide Reductases | 1980 |
2 trial(s) available for biotin and warfarin
| Article | Year |
|---|---|
Enoxaparin followed by once-weekly idrabiotaparinux versus enoxaparin plus warfarin for patients with acute symptomatic pulmonary embolism: a randomised, double-blind, double-dummy, non-inferiority trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Biotin; Double-Blind Method; Drug Therapy, Combination; Enoxaparin; Factor X; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Oligosaccharides; Pulmonary Embolism; Warfarin | 2012 |
Comparison of idrabiotaparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: the Borealis-Atrial Fibrillation Study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Biotin; Double-Blind Method; Drug Administration Schedule; Early Termination of Clinical Trials; Electrocardiography; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Oligosaccharides; Predictive Value of Tests; Risk Factors; Stroke; Thromboembolism; Time Factors; Treatment Outcome; Vitamin K; Warfarin | 2014 |
22 other study(ies) available for biotin and warfarin
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Separation of biotin and its analogs by high-performance liquid chromatography: convenient labeling for ultraviolet or fluorimetric detection.
Topics: Acetophenones; Biotin; Chromatography, High Pressure Liquid; Coumarins; Fluorometry; Spectrophotometry, Ultraviolet | 1983 |
Ultra-sensitive FISH using peroxidase-mediated deposition of biotin- or fluorochrome tyramides.
Topics: Animals; Biotin; Coumarins; Fluorescein; Fluoresceins; In Situ Hybridization, Fluorescence; Mice; Peroxidases; Rhodamines; Sensitivity and Specificity; Tyramine | 1995 |
Characterization of the cysteine proteinases of the common liver fluke Fasciola hepatica using novel, active-site directed affinity labels.
Topics: Affinity Labels; Animals; Biotin; Coumarins; Culture Media; Cysteine Endopeptidases; Diazomethane; Dipeptides; Fasciola hepatica; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Oligopeptides; Spectrometry, Fluorescence; Substrate Specificity | 1993 |
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
Topics: Age Factors; Animals; Antibody Specificity; Apoptosis; Biotin; Brain; Caspase 3; Caspases; Coumarins; Cysteine Endopeptidases; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; Ischemic Attack, Transient; Male; Mice; Mice, Inbred Strains; Oligopeptides; Staining and Labeling | 1998 |
Resin-supported labeling reagents.
Topics: Acridines; Biotin; Chromatography, High Pressure Liquid; Coumarins; Esters; Estriol; Fluorescein; Haptens; Phenytoin; Resins, Plant; Thyroxine | 1999 |
Detection of caspase-activation in intact lymphoid cells using standard caspase substrates and inhibitors.
Topics: Amino Acid Chloromethyl Ketones; Biotin; Biotinylation; Caspase 3; Caspase Inhibitors; Caspases; Coumarins; Enzyme Activation; Flow Cytometry; Humans; Jurkat Cells; Lymphoid Tissue; Oligopeptides; Spectrometry, Fluorescence | 2000 |
Site-directed incorporation of fluorescent nonnatural amino acids into streptavidin for highly sensitive detection of biotin.
Topics: Amino Acids; Biotin; Coumarins; Fluorescent Dyes; Indicators and Reagents; Mutation; Recombinant Proteins; RNA, Transfer; Spectrometry, Fluorescence; Streptavidin; Tryptophan | 2000 |
Chemical expansion of cofactor activity.
Topics: Adenosine Triphosphate; Affinity Labels; Binding Sites; Biotin; Carbon; Coenzyme A; Coenzymes; Coumarins; DNA; Enzyme Activation; Methylation; Methyltransferases; Models, Chemical; Pyridoxal Phosphate; S-Adenosylmethionine; Tetrahydrofolates | 2006 |
Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay.
Topics: Apoptosis; Biotin; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Inhibitory Concentration 50; Oligopeptides; Poly(ADP-ribose) Polymerase Inhibitors; Sensitivity and Specificity; Spectrin | 2006 |
Idrabiotaparinux treatment for venous thromboembolism.
Topics: Anticoagulants; Biotin; Enoxaparin; Factor X; Female; Humans; Male; Oligosaccharides; Pulmonary Embolism; Warfarin | 2012 |
Gemcitabine-coumarin-biotin conjugates: a target specific theranostic anticancer prodrug.
Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cell Survival; Coumarins; Deoxycytidine; Drug Delivery Systems; Fluorescent Dyes; Gemcitabine; Humans; Neoplasms; Prodrugs; Sulfhydryl Compounds | 2013 |
Discovery of coumarin derivatives as fluorescence acceptors for intrinsic fluorescence resonance energy transfer of proteins.
Topics: Biotin; Coumarins; Fluorescence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Proteins; Streptavidin; Tryptophan | 2014 |
Rational design of biotin-disulfide-coumarin conjugates: a cancer targeted thiol probe and bioimaging.
Topics: Biotin; Cell Line, Tumor; Coumarins; Disulfides; Endocytosis; Fluorescent Dyes; Humans; Molecular Probes; Neoplasms; Optical Imaging; Receptors, Growth Factor | 2014 |
Clinical trials and tribulations.
Topics: Anticoagulants; Atrial Fibrillation; Biotin; Factor Xa Inhibitors; Female; Humans; Male; Oligosaccharides; Stroke; Thromboembolism; Vitamin K; Warfarin | 2014 |
Terminated.
Topics: Anticoagulants; Atrial Fibrillation; Biotin; Factor Xa Inhibitors; Female; Humans; Male; Oligosaccharides; Stroke; Thromboembolism; Vitamin K; Warfarin | 2014 |
Rational design of biotinylated probes: fluorescent turn-on detection of (strept)avidin and bioimaging in cancer cells.
Topics: Avidin; Biotin; Coumarins; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Molecular Structure; Receptors, Growth Factor; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Streptavidin | 2014 |
Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2.
Topics: Amines; Aminoacetonitrile; Animals; Antioxidants; Biotin; Coumarins; Dithiothreitol; Enzyme Assays; Fluorescent Dyes; Glutamates; GTP-Binding Proteins; Guinea Pigs; Humans; Iodoacetamide; Kinetics; Lysine; Oligopeptides; Phosphines; Piperazines; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases | 2016 |
Probing Deviation of Adhered Membrane Dynamics between Reconstituted Liposome and Cellular System.
Topics: Animals; Avidin; Biotin; Cell Adhesion; Cell Membrane; CHO Cells; Coumarins; Cricetulus; Fluorescein; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Liposomes; Maleimides; Microscopy, Confocal; Microscopy, Fluorescence; Oxazines; Rhodamines | 2019 |