Page last updated: 2024-09-05

biotin and warfarin

biotin has been researched along with warfarin in 25 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(warfarin)
Trials
(warfarin)
Recent Studies (post-2010) (warfarin)
14,847953,88236,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.00)18.7374
1990's4 (16.00)18.2507
2000's4 (16.00)29.6817
2010's14 (56.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Suttie, JW1
Coustal, S; Desbene, PL; Frappier, F1
Raap, AK; Tanke, HJ; van de Corput, MP; van Gijlswijk, RP; Vervenne, RA; Wiegant, J1
Halton, DW; McGinty, A; Moore, M; Walker, B1
Endres, M; Fink, K; Moskowitz, MA; Namura, S; Srinivasan, A; Tomaselli, KJ; Yuan, J; Zhu, J1
Adamczyk, M; Fishpaugh, JR; Mattingly, PG1
Fürmann, C; Häcker, G; Mack, A1
Ashizuka, Y; Hashimoto, K; Hohsaka, T; Murakami, H; Sisido, M1
Burkart, MD; Mercer, AC1
Giroux, A; Grimm, E; Han, Y; Nicholson, DW; Tawa, P; Xanthoudakis, S1
Eikelboom, JW; Weitz, JI1
Büller, HR; Gallus, AS; Pillion, G; Prins, MH; Raskob, GE1
Bhuniya, S; Han, JH; Jeon, HM; Kang, C; Kim, JS; Lee, JH; Maiti, S; Park, N1
Chung, SJ; Kang, HJ; Kim, JH; Sumranjit, J1
Jung, D; Kim, JS; Lee, JH; Maiti, S1
Buller, HR; Halperin, J; Hankey, GJ; Pillion, G; Prins, MH; Raskob, GE1
Greaves, M1
Reitsma, PH; Rosendaal, FR1
Duan, L; Qian, J; Sun, Q; Tian, H; Zhang, W1
Löser, R; Pietsch, M; Pietzsch, J; Schramm, G; Wodtke, R1
Amin, MA; Bhattacharyya, K; Chowdhury, R; Ghosh, S; Mondal, P; Nandi, S1

Reviews

1 review(s) available for biotin and warfarin

ArticleYear
Mechanism of action of vitamin K: synthesis of gamma-carboxyglutamic acid.
    CRC critical reviews in biochemistry, 1980, Volume: 8, Issue:2

    Topics: 1-Carboxyglutamic Acid; Adenosine Triphosphate; Animals; Biotin; Carbon Dioxide; Carbon-Carbon Ligases; Coumarins; Glutamates; Humans; Ligases; Mixed Function Oxygenases; Molecular Conformation; Oxygen; Prothrombin; Substrate Specificity; Vitamin K; Vitamin K Epoxide Reductases

1980

Trials

2 trial(s) available for biotin and warfarin

ArticleYear
Enoxaparin followed by once-weekly idrabiotaparinux versus enoxaparin plus warfarin for patients with acute symptomatic pulmonary embolism: a randomised, double-blind, double-dummy, non-inferiority trial.
    Lancet (London, England), 2012, Jan-14, Volume: 379, Issue:9811

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Biotin; Double-Blind Method; Drug Therapy, Combination; Enoxaparin; Factor X; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Oligosaccharides; Pulmonary Embolism; Warfarin

2012
Comparison of idrabiotaparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: the Borealis-Atrial Fibrillation Study.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Biotin; Double-Blind Method; Drug Administration Schedule; Early Termination of Clinical Trials; Electrocardiography; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Oligosaccharides; Predictive Value of Tests; Risk Factors; Stroke; Thromboembolism; Time Factors; Treatment Outcome; Vitamin K; Warfarin

2014

Other Studies

22 other study(ies) available for biotin and warfarin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Separation of biotin and its analogs by high-performance liquid chromatography: convenient labeling for ultraviolet or fluorimetric detection.
    Analytical biochemistry, 1983, Feb-01, Volume: 128, Issue:2

    Topics: Acetophenones; Biotin; Chromatography, High Pressure Liquid; Coumarins; Fluorometry; Spectrophotometry, Ultraviolet

1983
Ultra-sensitive FISH using peroxidase-mediated deposition of biotin- or fluorochrome tyramides.
    Human molecular genetics, 1995, Volume: 4, Issue:4

    Topics: Animals; Biotin; Coumarins; Fluorescein; Fluoresceins; In Situ Hybridization, Fluorescence; Mice; Peroxidases; Rhodamines; Sensitivity and Specificity; Tyramine

1995
Characterization of the cysteine proteinases of the common liver fluke Fasciola hepatica using novel, active-site directed affinity labels.
    Parasitology, 1993, Volume: 106 ( Pt 5)

    Topics: Affinity Labels; Animals; Biotin; Coumarins; Culture Media; Cysteine Endopeptidases; Diazomethane; Dipeptides; Fasciola hepatica; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Oligopeptides; Spectrometry, Fluorescence; Substrate Specificity

1993
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, May-15, Volume: 18, Issue:10

    Topics: Age Factors; Animals; Antibody Specificity; Apoptosis; Biotin; Brain; Caspase 3; Caspases; Coumarins; Cysteine Endopeptidases; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; Ischemic Attack, Transient; Male; Mice; Mice, Inbred Strains; Oligopeptides; Staining and Labeling

1998
Resin-supported labeling reagents.
    Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2

    Topics: Acridines; Biotin; Chromatography, High Pressure Liquid; Coumarins; Esters; Estriol; Fluorescein; Haptens; Phenytoin; Resins, Plant; Thyroxine

1999
Detection of caspase-activation in intact lymphoid cells using standard caspase substrates and inhibitors.
    Journal of immunological methods, 2000, Jul-31, Volume: 241, Issue:1-2

    Topics: Amino Acid Chloromethyl Ketones; Biotin; Biotinylation; Caspase 3; Caspase Inhibitors; Caspases; Coumarins; Enzyme Activation; Flow Cytometry; Humans; Jurkat Cells; Lymphoid Tissue; Oligopeptides; Spectrometry, Fluorescence

2000
Site-directed incorporation of fluorescent nonnatural amino acids into streptavidin for highly sensitive detection of biotin.
    Biomacromolecules, 2000,Spring, Volume: 1, Issue:1

    Topics: Amino Acids; Biotin; Coumarins; Fluorescent Dyes; Indicators and Reagents; Mutation; Recombinant Proteins; RNA, Transfer; Spectrometry, Fluorescence; Streptavidin; Tryptophan

2000
Chemical expansion of cofactor activity.
    Nature chemical biology, 2006, Volume: 2, Issue:1

    Topics: Adenosine Triphosphate; Affinity Labels; Binding Sites; Biotin; Carbon; Coenzyme A; Coenzymes; Coumarins; DNA; Enzyme Activation; Methylation; Methyltransferases; Models, Chemical; Pyridoxal Phosphate; S-Adenosylmethionine; Tetrahydrofolates

2006
Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay.
    Analytical biochemistry, 2006, Mar-01, Volume: 350, Issue:1

    Topics: Apoptosis; Biotin; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Inhibitory Concentration 50; Oligopeptides; Poly(ADP-ribose) Polymerase Inhibitors; Sensitivity and Specificity; Spectrin

2006
Idrabiotaparinux treatment for venous thromboembolism.
    Lancet (London, England), 2012, Jan-14, Volume: 379, Issue:9811

    Topics: Anticoagulants; Biotin; Enoxaparin; Factor X; Female; Humans; Male; Oligosaccharides; Pulmonary Embolism; Warfarin

2012
Gemcitabine-coumarin-biotin conjugates: a target specific theranostic anticancer prodrug.
    Journal of the American Chemical Society, 2013, Mar-20, Volume: 135, Issue:11

    Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cell Survival; Coumarins; Deoxycytidine; Drug Delivery Systems; Fluorescent Dyes; Gemcitabine; Humans; Neoplasms; Prodrugs; Sulfhydryl Compounds

2013
Discovery of coumarin derivatives as fluorescence acceptors for intrinsic fluorescence resonance energy transfer of proteins.
    Molecular bioSystems, 2014, Volume: 10, Issue:1

    Topics: Biotin; Coumarins; Fluorescence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Proteins; Streptavidin; Tryptophan

2014
Rational design of biotin-disulfide-coumarin conjugates: a cancer targeted thiol probe and bioimaging.
    Chemical communications (Cambridge, England), 2014, Mar-21, Volume: 50, Issue:23

    Topics: Biotin; Cell Line, Tumor; Coumarins; Disulfides; Endocytosis; Fluorescent Dyes; Humans; Molecular Probes; Neoplasms; Optical Imaging; Receptors, Growth Factor

2014
Clinical trials and tribulations.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:6

    Topics: Anticoagulants; Atrial Fibrillation; Biotin; Factor Xa Inhibitors; Female; Humans; Male; Oligosaccharides; Stroke; Thromboembolism; Vitamin K; Warfarin

2014
Terminated.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:6

    Topics: Anticoagulants; Atrial Fibrillation; Biotin; Factor Xa Inhibitors; Female; Humans; Male; Oligosaccharides; Stroke; Thromboembolism; Vitamin K; Warfarin

2014
Rational design of biotinylated probes: fluorescent turn-on detection of (strept)avidin and bioimaging in cancer cells.
    Chemical communications (Cambridge, England), 2014, Aug-11, Volume: 50, Issue:62

    Topics: Avidin; Biotin; Coumarins; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Molecular Structure; Receptors, Growth Factor; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Streptavidin

2014
Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2.
    Chembiochem : a European journal of chemical biology, 2016, 07-01, Volume: 17, Issue:13

    Topics: Amines; Aminoacetonitrile; Animals; Antioxidants; Biotin; Coumarins; Dithiothreitol; Enzyme Assays; Fluorescent Dyes; Glutamates; GTP-Binding Proteins; Guinea Pigs; Humans; Iodoacetamide; Kinetics; Lysine; Oligopeptides; Phosphines; Piperazines; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases

2016
Probing Deviation of Adhered Membrane Dynamics between Reconstituted Liposome and Cellular System.
    Chemistry, an Asian journal, 2019, Dec-13, Volume: 14, Issue:24

    Topics: Animals; Avidin; Biotin; Cell Adhesion; Cell Membrane; CHO Cells; Coumarins; Cricetulus; Fluorescein; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Liposomes; Maleimides; Microscopy, Confocal; Microscopy, Fluorescence; Oxazines; Rhodamines

2019