Compounds > biotin
Page last updated: 2024-09-05

biotin and methadone

biotin has been researched along with methadone in 4 studies

Compound Research Comparison

Studies
(biotin)		Trials
(biotin)		Recent Studies (post-2010)
(biotin)		Studies
(methadone)		Trials
(methadone)		Recent Studies (post-2010) (methadone)
14,847953,88213,6301,4633,957

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)methadone (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)7.5
Mu-type opioid receptorHomo sapiens (human)0.0041
Delta-type opioid receptorHomo sapiens (human)1.09
Kappa-type opioid receptorHomo sapiens (human)0.512
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)9.7724

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
He, L; Whistler, JL1
Livingston, KE; Mahoney, JP; Manglik, A; Sunahara, RK; Traynor, JR1

Other Studies

4 other study(ies) available for biotin and methadone

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
An opiate cocktail that reduces morphine tolerance and dependence.
    Current biology : CB, 2005, Jun-07, Volume: 15, Issue:11

    Topics: Analysis of Variance; Animals; Biotin; Blotting, Western; Cyclic AMP; Drug Combinations; Drug Tolerance; Endocytosis; Immunohistochemistry; Luciferases; Methadone; Morphine; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substance-Related Disorders

2005
Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor.
    eLife, 2018, 06-22, Volume: 7

    Topics: Allosteric Regulation; Allosteric Site; Biosensing Techniques; Biotin; Humans; Interferometry; Ligands; Loperamide; Methadone; Protein Binding; Receptors, Opioid, mu; Sensitivity and Specificity; Single-Domain Antibodies; Small Molecule Libraries; Solutions; Streptavidin; Thiophenes; Urea

2018