biotin and isoniazid
biotin has been researched along with isoniazid in 8 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (isoniazid) | Trials (isoniazid) | Recent Studies (post-2010) (isoniazid) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 21,815 | 960 | 4,493 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | isoniazid (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 4.85 | |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | 8.29 | |
| Putative FAD-containing monooxygenase MymA | Mycobacterium tuberculosis H37Rv | 4.9 |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bonanni, LC; Divo, AA; Geary, TG; Jensen, JB | 1 |
| Ha, KS; Jung, SH; Kim, YM; Kong, DH; Kwon, MH; Suh, IB | 1 |
| Bank, S; Heller, E; Holzgrabe, U; Kapková, P; Memmel, E; Seibel, J | 1 |
| Bond, TEH; Schaeffer, PM; Sorenson, AE | 1 |
| Aoki, S; Baba, H; Kawashima, S; Komatsu, H; Maruoka, T; Morita, K; Sacchettini, JC; Sakamoto, H; Taira, J; Umei, T | 1 |
Other Studies
8 other study(ies) available for biotin and isoniazid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites.
Topics: 4-Aminobenzoic Acid; Animals; Antimetabolites; Biotin; Buthionine Sulfoximine; Carbohydrate Metabolism; Culture Media; Dipyridamole; Folic Acid; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Isoniazid; Leucovorin; Methionine Sulfoximine; Plasmodium falciparum; Purines; Pyridoxine; Sulfonamides | 1985 |
Rapid determination of blood coagulation factor XIII activity using protein arrays for serodiagnosis of human plasma.
Topics: Amines; Biomarkers, Tumor; Biotin; Blood Specimen Collection; Carcinoma, Hepatocellular; Factor XIII; Fibrinogen; Hepatitis; Humans; Immobilized Proteins; Isoniazid; Limit of Detection; Liver Cirrhosis; Liver Neoplasms; Protein Array Analysis; Reproducibility of Results; Serologic Tests; Time Factors | 2011 |
Matrix-assisted laser desorption/ionization tandem mass spectrometry of N-glycans derivatized with isonicotinic hydrazide and its biotinylated form.
Topics: Biotin; Biotinylation; Isoniazid; Ovalbumin; Polysaccharides; Ribonucleases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2014 |
A green fluorescent protein-based assay for high-throughput ligand-binding studies of a mycobacterial biotin protein ligase.
Topics: Acetyl-CoA Carboxylase; Adenosine Triphosphate; Biotin; Calorimetry, Differential Scanning; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Gene Expression Regulation, Bacterial; Genetic Vectors; Green Fluorescent Proteins; High-Throughput Screening Assays; Isoniazid; Mycobacterium tuberculosis; Protein Refolding; Sulfurtransferases | 2017 |
Identification of a novel class of small compounds with anti-tuberculosis activity by in silico structure-based drug screening.
Topics: Antitubercular Agents; Biotin; Computer Simulation; Drug Design; Isoniazid; Mycobacterium smegmatis; Mycobacterium tuberculosis; Small Molecule Libraries; Structure-Activity Relationship; Tuberculosis | 2017 |