Compounds > biotin
Page last updated: 2024-09-05

biotin and isoniazid

biotin has been researched along with isoniazid in 8 studies

Compound Research Comparison

Studies
(biotin)		Trials
(biotin)		Recent Studies (post-2010)
(biotin)		Studies
(isoniazid)		Trials
(isoniazid)		Recent Studies (post-2010) (isoniazid)
14,847953,88221,8159604,493

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)isoniazid (IC50)
MyeloperoxidaseHomo sapiens (human)4.85
Enoyl-[acyl-carrier-protein] reductase [NADH]Mycobacterium tuberculosis H37Rv8.29
Putative FAD-containing monooxygenase MymAMycobacterium tuberculosis H37Rv4.9

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bonanni, LC; Divo, AA; Geary, TG; Jensen, JB1
Ha, KS; Jung, SH; Kim, YM; Kong, DH; Kwon, MH; Suh, IB1
Bank, S; Heller, E; Holzgrabe, U; Kapková, P; Memmel, E; Seibel, J1
Bond, TEH; Schaeffer, PM; Sorenson, AE1
Aoki, S; Baba, H; Kawashima, S; Komatsu, H; Maruoka, T; Morita, K; Sacchettini, JC; Sakamoto, H; Taira, J; Umei, T1

Other Studies

8 other study(ies) available for biotin and isoniazid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites.
    The Journal of protozoology, 1985, Volume: 32, Issue:4

    Topics: 4-Aminobenzoic Acid; Animals; Antimetabolites; Biotin; Buthionine Sulfoximine; Carbohydrate Metabolism; Culture Media; Dipyridamole; Folic Acid; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Isoniazid; Leucovorin; Methionine Sulfoximine; Plasmodium falciparum; Purines; Pyridoxine; Sulfonamides

1985
Rapid determination of blood coagulation factor XIII activity using protein arrays for serodiagnosis of human plasma.
    Analytical chemistry, 2011, Mar-15, Volume: 83, Issue:6

    Topics: Amines; Biomarkers, Tumor; Biotin; Blood Specimen Collection; Carcinoma, Hepatocellular; Factor XIII; Fibrinogen; Hepatitis; Humans; Immobilized Proteins; Isoniazid; Limit of Detection; Liver Cirrhosis; Liver Neoplasms; Protein Array Analysis; Reproducibility of Results; Serologic Tests; Time Factors

2011
Matrix-assisted laser desorption/ionization tandem mass spectrometry of N-glycans derivatized with isonicotinic hydrazide and its biotinylated form.
    Rapid communications in mass spectrometry : RCM, 2014, Aug-15, Volume: 28, Issue:15

    Topics: Biotin; Biotinylation; Isoniazid; Ovalbumin; Polysaccharides; Ribonucleases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry

2014
A green fluorescent protein-based assay for high-throughput ligand-binding studies of a mycobacterial biotin protein ligase.
    Microbiological research, 2017, Volume: 205

    Topics: Acetyl-CoA Carboxylase; Adenosine Triphosphate; Biotin; Calorimetry, Differential Scanning; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Gene Expression Regulation, Bacterial; Genetic Vectors; Green Fluorescent Proteins; High-Throughput Screening Assays; Isoniazid; Mycobacterium tuberculosis; Protein Refolding; Sulfurtransferases

2017
Identification of a novel class of small compounds with anti-tuberculosis activity by in silico structure-based drug screening.
    The Journal of antibiotics, 2017, Volume: 70, Issue:11

    Topics: Antitubercular Agents; Biotin; Computer Simulation; Drug Design; Isoniazid; Mycobacterium smegmatis; Mycobacterium tuberculosis; Small Molecule Libraries; Structure-Activity Relationship; Tuberculosis

2017