Page last updated: 2024-09-05

biotin and cyclic gmp

biotin has been researched along with cyclic gmp in 20 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(cyclic gmp)
Trials
(cyclic gmp)
Recent Studies (post-2010) (cyclic gmp)
14,847953,88222,3463334,062

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's5 (25.00)18.2507
2000's5 (25.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dakshinamurti, K; Singh, IN1
Koudelka, AP; Spence, JT1
Dressendörfer, RA; Gerzer, R; Heim, JM; Strasburger, CJ1
Rörig, B; Sutor, B1
Classen, M; Mahr, S; Neumayer, N; Prinz, C; Schepp, W1
Ren, Q; Stockert, RJ1
Alpert, C; Barnard, MR; Freedman, JE; Keaney, JF; Loscalzo, J; Michelson, AD1
León-Del-Río, A; Pacheco-Alvarez, D; Solórzano-Vargas, RS1
McCarty, MF2
Marletta, MA; Mitchell, DA; Morton, SU1
Cervantes-Roldán, R; González-Noriega, A; Gravel, RA; León-Del-Río, A; Meneses-Morales, I; Pérez-Monjaras, A; Reyes-Carmona, S; Solórzano-Vargas, S1
Fernandez-Mejia, C; Marin-Hernandez, A; Rojas-Ochoa, A; Tovar, AR; Vilches-Flores, A1
Becirovic, E; Biel, M; Hammelmann, V; Michalakis, S; Wanner, KT; Wein, T; Zong, X1
Jang, JH; Kim, DH; Lee, C; Surh, YJ; Um, HC1
Dayie, TK; Lee, VT; Luo, Y; Sintim, HO; Watt, SK; Zhou, J1
Challiss, RA; Cooke, RM; Mistry, R; Straub, VA1
Aguilera-Méndez, A; Boone-Villa, D; Fernandez-Mejia, C; Miranda-Cervantes, A1
DiNicolantonio, JJ; McCarty, MF1

Other Studies

20 other study(ies) available for biotin and cyclic gmp

ArticleYear
Stimulation of guanylate cyclase and RNA polymerase II activities in HeLa cells and fibroblasts by biotin.
    Molecular and cellular biochemistry, 1988, Volume: 79, Issue:1

    Topics: Biotin; Cells, Cultured; Cyclic GMP; Enzyme Activation; Fibroblasts; Guanylate Cyclase; HeLa Cells; Humans; RNA Polymerase II

1988
Biotin increases cGMP and glucokinase in liver cells.
    Nutrition reviews, 1984, Volume: 42, Issue:10

    Topics: Animals; Biotin; Cells, Cultured; Cyclic GMP; Glucokinase; Insulin; Liver; Male; Rats

1984
Effects of biotin upon the intracellular level of cGMP and the activity of glucokinase in cultured rat hepatocytes.
    The Journal of biological chemistry, 1984, May-25, Volume: 259, Issue:10

    Topics: Acetylglucosamine; Animals; Biotin; Cells, Cultured; Cyclic GMP; Glucokinase; Glucose; Kinetics; Liver; Male; Protein Biosynthesis; Rabbits; Rats; Rats, Inbred Strains; Reticulocytes; RNA, Messenger; Transcription, Genetic

1984
A non-isotopic immunoassay for guanosine 3':5'-cyclic monophosphate using a cyclic GMP-biotin conjugate as tracer.
    Journal of immunoassay, 1995, Volume: 16, Issue:1

    Topics: Biotin; Chromatography, Liquid; Cyclic GMP; Immunoassay; Reproducibility of Results; Sensitivity and Specificity

1995
Nitric oxide-stimulated increase in intracellular cGMP modulates gap junction coupling in rat neocortex.
    Neuroreport, 1996, Jan-31, Volume: 7, Issue:2

    Topics: Animals; Biotin; Cerebral Cortex; Cyclic GMP; Female; Gap Junctions; Male; Membrane Potentials; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar

1996
Functional impairment of rat enterochromaffin-like cells by interleukin 1 beta.
    Gastroenterology, 1997, Volume: 112, Issue:2

    Topics: Animals; Biotin; Cyclic GMP; Dinoprostone; DNA, Complementary; Enterochromaffin Cells; Epinephrine; Female; Gastrins; Gene Library; Histamine Release; Histidine Decarboxylase; Interleukin-1; Interleukins; L-Lactate Dehydrogenase; Nitric Oxide; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Time Factors

1997
Cytoplasmic protein mRNA interaction mediates cGMP-modulated translational control of the asialoglycoprotein receptor.
    The Journal of biological chemistry, 1997, Apr-04, Volume: 272, Issue:14

    Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Biotin; Carcinoma, Hepatocellular; COS Cells; Cyclic GMP; Guanosine; Humans; Liver Neoplasms; Protein Biosynthesis; Receptors, Cell Surface; Restriction Mapping; RNA, Messenger; Transfection; Tumor Cells, Cultured

1997
Nitric oxide released from activated platelets inhibits platelet recruitment.
    The Journal of clinical investigation, 1997, Jul-15, Volume: 100, Issue:2

    Topics: Adenosine Diphosphate; Adult; Biotin; Blood Platelets; Cyclic GMP; Cytoplasmic Granules; Flow Cytometry; Humans; Microelectrodes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; P-Selectin; Platelet Activation; Platelet Aggregation; Serotonin; Thrombosis

1997
Holocarboxylase synthetase is an obligate participant in biotin-mediated regulation of its own expression and of biotin-dependent carboxylases mRNA levels in human cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Apr-16, Volume: 99, Issue:8

    Topics: Biotin; Carbon-Carbon Ligases; Carbon-Nitrogen Ligases; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dactinomycin; Densitometry; Dose-Response Relationship, Drug; Fibroblasts; Guanylate Cyclase; Humans; Mutation; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Vitamins

2002
High-dose biotin may down-regulate hepatic expression of acute phase reactants by mimicking the physiological role of nitric oxide.
    Medical hypotheses, 2003, Volume: 61, Issue:4

    Topics: Acute-Phase Reaction; Animals; Biotin; Cells, Cultured; Cyclic GMP; DNA-Binding Proteins; Down-Regulation; Humans; Inflammation; Interleukin-6; Liver; Models, Theoretical; Nitric Oxide; Rats; Signal Transduction; STAT3 Transcription Factor; Trans-Activators

2003
cGMP may have trophic effects on beta cell function comparable to those of cAMP, implying a role for high-dose biotin in prevention/treatment of diabetes.
    Medical hypotheses, 2006, Volume: 66, Issue:2

    Topics: Animals; Biotin; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; Islets of Langerhans

2006
Design and characterization of an active site selective caspase-3 transnitrosating agent.
    ACS chemical biology, 2006, Nov-21, Volume: 1, Issue:10

    Topics: Apoptosis; Binding Sites; Biotin; Caspase 3; Caspase 9; Chemistry, Pharmaceutical; Cyclic GMP; Cysteine; Drug Design; Enzyme Activation; Humans; Kinetics; Nitric Oxide; Nitrosation; Peptides

2006
Impaired biotinidase activity disrupts holocarboxylase synthetase expression in late onset multiple carboxylase deficiency.
    The Journal of biological chemistry, 2008, Dec-05, Volume: 283, Issue:49

    Topics: Amino Acid Sequence; Animals; Base Sequence; Biotin; Biotinidase; Biotinidase Deficiency; Brain; Carbon-Nitrogen Ligases; Cell Culture Techniques; Cyclic GMP; Holocarboxylase Synthetase Deficiency; Humans; Models, Biological; Molecular Sequence Data; Transcription, Genetic

2008
Biotin increases glucokinase expression via soluble guanylate cyclase/protein kinase G, adenosine triphosphate production and autocrine action of insulin in pancreatic rat islets.
    The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:7

    Topics: Adenosine Triphosphate; Animals; Autocrine Communication; Biotin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucokinase; Guanylate Cyclase; Insulin; Insulin Antagonists; Islets of Langerhans; Kinetics; Male; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Soluble Guanylyl Cyclase

2010
The glutamic acid-rich protein is a gating inhibitor of cyclic nucleotide-gated channels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jan-05, Volume: 31, Issue:1

    Topics: Amino Acid Sequence; Animals; Biophysical Phenomena; Biotin; Biotinylation; Cell Line, Transformed; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Fluorescence Resonance Energy Transfer; Gene Expression Regulation; Humans; Immunoprecipitation; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Succinimides; Transfection

2011
Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells.
    Nitric oxide : biology and chemistry, 2011, Aug-01, Volume: 25, Issue:2

    Topics: Animals; Biotin; Blotting, Western; Cell Nucleus; Cyclic GMP; Disulfides; Electrophoretic Mobility Shift Assay; Enzyme Activation; Fluorescent Antibody Technique; Heme Oxygenase (Decyclizing); Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Nitric Oxide; PC12 Cells; Phosphorylation; Protein Kinase C; Proteins; Rats; S-Nitrosothiols; Signal Transduction; Staurosporine

2011
Differential binding of 2'-biotinylated analogs of c-di-GMP with c-di-GMP riboswitches and binding proteins.
    Molecular bioSystems, 2012, Volume: 8, Issue:3

    Topics: Bacterial Proteins; Biotin; Biotinylation; Carrier Proteins; Cyclic GMP; Ligands; Models, Molecular; Nucleic Acid Conformation; Riboswitch; RNA, Bacterial; Solid-Phase Synthesis Techniques; Vibrio cholerae

2012
Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-27, Volume: 33, Issue:13

    Topics: Action Potentials; Analysis of Variance; Animals; Axotomy; Biophysics; Biotin; Cells, Cultured; Central Nervous System; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Hydrazines; Iontophoresis; Neurites; Neurons; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Snails; Synapses

2013
Effects of Biotin Supplementation in the Diet on Adipose Tissue cGMP Concentrations, AMPK Activation, Lipolysis, and Serum-Free Fatty Acid Levels.
    Journal of medicinal food, 2015, Volume: 18, Issue:10

    Topics: Acetyl-CoA Carboxylase; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Biotin; Cyclic GMP; Dietary Supplements; Enzyme Activation; Fatty Acids, Nonesterified; Lipolysis; Male; Mice; Mice, Inbred BALB C; Phosphorylation

2015
Neuroprotective potential of high-dose biotin.
    Medical hypotheses, 2017, Volume: 109

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Biotin; Brain; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Extracellular Signal-Regulated MAP Kinases; Humans; Long-Term Potentiation; Microcirculation; Multiple Sclerosis; Neurogenesis; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Randomized Controlled Trials as Topic; Signal Transduction

2017