biotin and cyclic gmp
biotin has been researched along with cyclic gmp in 20 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (cyclic gmp) | Trials (cyclic gmp) | Recent Studies (post-2010) (cyclic gmp) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 22,346 | 333 | 4,062 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | cyclic gmp (IC50) |
|---|---|---|---|
| Phosphodiesterase | Bos taurus (cattle) | 0.1 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | 2.4 | |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | 2.4 |
Research
Studies (20)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Dakshinamurti, K; Singh, IN | 1 |
| Koudelka, AP; Spence, JT | 1 |
| Dressendörfer, RA; Gerzer, R; Heim, JM; Strasburger, CJ | 1 |
| Rörig, B; Sutor, B | 1 |
| Classen, M; Mahr, S; Neumayer, N; Prinz, C; Schepp, W | 1 |
| Ren, Q; Stockert, RJ | 1 |
| Alpert, C; Barnard, MR; Freedman, JE; Keaney, JF; Loscalzo, J; Michelson, AD | 1 |
| León-Del-Río, A; Pacheco-Alvarez, D; Solórzano-Vargas, RS | 1 |
| McCarty, MF | 2 |
| Marletta, MA; Mitchell, DA; Morton, SU | 1 |
| Cervantes-Roldán, R; González-Noriega, A; Gravel, RA; León-Del-Río, A; Meneses-Morales, I; Pérez-Monjaras, A; Reyes-Carmona, S; Solórzano-Vargas, S | 1 |
| Fernandez-Mejia, C; Marin-Hernandez, A; Rojas-Ochoa, A; Tovar, AR; Vilches-Flores, A | 1 |
| Becirovic, E; Biel, M; Hammelmann, V; Michalakis, S; Wanner, KT; Wein, T; Zong, X | 1 |
| Jang, JH; Kim, DH; Lee, C; Surh, YJ; Um, HC | 1 |
| Dayie, TK; Lee, VT; Luo, Y; Sintim, HO; Watt, SK; Zhou, J | 1 |
| Challiss, RA; Cooke, RM; Mistry, R; Straub, VA | 1 |
| Aguilera-Méndez, A; Boone-Villa, D; Fernandez-Mejia, C; Miranda-Cervantes, A | 1 |
| DiNicolantonio, JJ; McCarty, MF | 1 |
Other Studies
20 other study(ies) available for biotin and cyclic gmp
| Article | Year |
|---|---|
Stimulation of guanylate cyclase and RNA polymerase II activities in HeLa cells and fibroblasts by biotin.
Topics: Biotin; Cells, Cultured; Cyclic GMP; Enzyme Activation; Fibroblasts; Guanylate Cyclase; HeLa Cells; Humans; RNA Polymerase II | 1988 |
Biotin increases cGMP and glucokinase in liver cells.
Topics: Animals; Biotin; Cells, Cultured; Cyclic GMP; Glucokinase; Insulin; Liver; Male; Rats | 1984 |
Effects of biotin upon the intracellular level of cGMP and the activity of glucokinase in cultured rat hepatocytes.
Topics: Acetylglucosamine; Animals; Biotin; Cells, Cultured; Cyclic GMP; Glucokinase; Glucose; Kinetics; Liver; Male; Protein Biosynthesis; Rabbits; Rats; Rats, Inbred Strains; Reticulocytes; RNA, Messenger; Transcription, Genetic | 1984 |
A non-isotopic immunoassay for guanosine 3':5'-cyclic monophosphate using a cyclic GMP-biotin conjugate as tracer.
Topics: Biotin; Chromatography, Liquid; Cyclic GMP; Immunoassay; Reproducibility of Results; Sensitivity and Specificity | 1995 |
Nitric oxide-stimulated increase in intracellular cGMP modulates gap junction coupling in rat neocortex.
Topics: Animals; Biotin; Cerebral Cortex; Cyclic GMP; Female; Gap Junctions; Male; Membrane Potentials; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar | 1996 |
Functional impairment of rat enterochromaffin-like cells by interleukin 1 beta.
Topics: Animals; Biotin; Cyclic GMP; Dinoprostone; DNA, Complementary; Enterochromaffin Cells; Epinephrine; Female; Gastrins; Gene Library; Histamine Release; Histidine Decarboxylase; Interleukin-1; Interleukins; L-Lactate Dehydrogenase; Nitric Oxide; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Cytoplasmic protein mRNA interaction mediates cGMP-modulated translational control of the asialoglycoprotein receptor.
Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Biotin; Carcinoma, Hepatocellular; COS Cells; Cyclic GMP; Guanosine; Humans; Liver Neoplasms; Protein Biosynthesis; Receptors, Cell Surface; Restriction Mapping; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1997 |
Nitric oxide released from activated platelets inhibits platelet recruitment.
Topics: Adenosine Diphosphate; Adult; Biotin; Blood Platelets; Cyclic GMP; Cytoplasmic Granules; Flow Cytometry; Humans; Microelectrodes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; P-Selectin; Platelet Activation; Platelet Aggregation; Serotonin; Thrombosis | 1997 |
Holocarboxylase synthetase is an obligate participant in biotin-mediated regulation of its own expression and of biotin-dependent carboxylases mRNA levels in human cells.
Topics: Biotin; Carbon-Carbon Ligases; Carbon-Nitrogen Ligases; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dactinomycin; Densitometry; Dose-Response Relationship, Drug; Fibroblasts; Guanylate Cyclase; Humans; Mutation; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Vitamins | 2002 |
High-dose biotin may down-regulate hepatic expression of acute phase reactants by mimicking the physiological role of nitric oxide.
Topics: Acute-Phase Reaction; Animals; Biotin; Cells, Cultured; Cyclic GMP; DNA-Binding Proteins; Down-Regulation; Humans; Inflammation; Interleukin-6; Liver; Models, Theoretical; Nitric Oxide; Rats; Signal Transduction; STAT3 Transcription Factor; Trans-Activators | 2003 |
cGMP may have trophic effects on beta cell function comparable to those of cAMP, implying a role for high-dose biotin in prevention/treatment of diabetes.
Topics: Animals; Biotin; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; Islets of Langerhans | 2006 |
Design and characterization of an active site selective caspase-3 transnitrosating agent.
Topics: Apoptosis; Binding Sites; Biotin; Caspase 3; Caspase 9; Chemistry, Pharmaceutical; Cyclic GMP; Cysteine; Drug Design; Enzyme Activation; Humans; Kinetics; Nitric Oxide; Nitrosation; Peptides | 2006 |
Impaired biotinidase activity disrupts holocarboxylase synthetase expression in late onset multiple carboxylase deficiency.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biotin; Biotinidase; Biotinidase Deficiency; Brain; Carbon-Nitrogen Ligases; Cell Culture Techniques; Cyclic GMP; Holocarboxylase Synthetase Deficiency; Humans; Models, Biological; Molecular Sequence Data; Transcription, Genetic | 2008 |
Biotin increases glucokinase expression via soluble guanylate cyclase/protein kinase G, adenosine triphosphate production and autocrine action of insulin in pancreatic rat islets.
Topics: Adenosine Triphosphate; Animals; Autocrine Communication; Biotin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucokinase; Guanylate Cyclase; Insulin; Insulin Antagonists; Islets of Langerhans; Kinetics; Male; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Soluble Guanylyl Cyclase | 2010 |
The glutamic acid-rich protein is a gating inhibitor of cyclic nucleotide-gated channels.
Topics: Amino Acid Sequence; Animals; Biophysical Phenomena; Biotin; Biotinylation; Cell Line, Transformed; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Electric Stimulation; Fluorescence Resonance Energy Transfer; Gene Expression Regulation; Humans; Immunoprecipitation; Ion Channel Gating; Luminescent Proteins; Membrane Potentials; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Succinimides; Transfection | 2011 |
Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells.
Topics: Animals; Biotin; Blotting, Western; Cell Nucleus; Cyclic GMP; Disulfides; Electrophoretic Mobility Shift Assay; Enzyme Activation; Fluorescent Antibody Technique; Heme Oxygenase (Decyclizing); Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Nitric Oxide; PC12 Cells; Phosphorylation; Protein Kinase C; Proteins; Rats; S-Nitrosothiols; Signal Transduction; Staurosporine | 2011 |
Differential binding of 2'-biotinylated analogs of c-di-GMP with c-di-GMP riboswitches and binding proteins.
Topics: Bacterial Proteins; Biotin; Biotinylation; Carrier Proteins; Cyclic GMP; Ligands; Models, Molecular; Nucleic Acid Conformation; Riboswitch; RNA, Bacterial; Solid-Phase Synthesis Techniques; Vibrio cholerae | 2012 |
Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy.
Topics: Action Potentials; Analysis of Variance; Animals; Axotomy; Biophysics; Biotin; Cells, Cultured; Central Nervous System; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Hydrazines; Iontophoresis; Neurites; Neurons; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Snails; Synapses | 2013 |
Effects of Biotin Supplementation in the Diet on Adipose Tissue cGMP Concentrations, AMPK Activation, Lipolysis, and Serum-Free Fatty Acid Levels.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Biotin; Cyclic GMP; Dietary Supplements; Enzyme Activation; Fatty Acids, Nonesterified; Lipolysis; Male; Mice; Mice, Inbred BALB C; Phosphorylation | 2015 |
Neuroprotective potential of high-dose biotin.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Biotin; Brain; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Extracellular Signal-Regulated MAP Kinases; Humans; Long-Term Potentiation; Microcirculation; Multiple Sclerosis; Neurogenesis; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Randomized Controlled Trials as Topic; Signal Transduction | 2017 |