Page last updated: 2024-08-24

adenosine and naloxone

adenosine has been researched along with naloxone in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199028 (41.79)18.7374
1990's20 (29.85)18.2507
2000's11 (16.42)29.6817
2010's8 (11.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Daly, JW; Dismukes, K1
Perkins, MN; Stone, TW2
Klee, WA; Nirenberg, M; Sharma, SK2
De Koninck, Y; Henry, JL1
Coupar, IM; Dionyssopoulos, T; Hope, W1
Contreras, E; Germany, A; Villar, M1
Contreras, E; Germany, A; Quijada, L; Villar, M1
DeLander, GE; Hopkins, CJ1
Doi, T; Kuzuna, S; Maki, Y1
Adamson, P; Brammer, MJ; Campbell, IC; Hajimohammadreza, I; Mantzouridis, T; Xiang, JZ1
Ellis, JL; Farmer, SG1
Beermann, B; Brandt, R; Jonzon, B; Sylvén, C1
Dowell, RT; Eldridge, FL; Paydarfar, D; Scott, SC1
Hogenboom, F; Mulder, AH; Schoffelmeer, AN1
Huttunen, P; Puurunen, J1
DeTurck, KH; Pohorecky, LA1
Henry, JL; Salter, MW1
Bray, GA; Fisler, JS1
Law, PY; Loh, HH; Louie, AK1
Collier, HO; Tucker, JF1
Ammon, HP1
Collier, HO; Plant, NT; Tucker, JF; von Uexküll, A1
Lawson, EE; Long, WA1
Iverson, LL1
Breese, GR; Mueller, RA; Widerlöv, E1
Slater, P1
North, RA; Vitek, LV1
Phillis, JW; Wu, PH; Yuen, H1
McQueen, DS; Ribeiro, JA1
Chelack, BJ; Jiang, ZG; Phillis, JW; Wu, PH1
Gibbons, JM; Gibbons, WA; Nicolaou, A1
Chen, JY; Dafny, N; Qiao, JT; Xie, YF; Yang, SW; Zhang, ZH2
Richardson, PJ; Sirinathsinghji, DJ; Vellucci, SV1
Miranda, HF; Sierralta, F1
Joran, ME; Murphy, DJ; Renninger, JE1
Araki, T; Kanai, Y; Kato, H; Kogure, K1
Aley, KO; Green, PG; Levine, JD1
Aley, KO; Levine, JD1
Coupar, IM; Hancock, DL1
Dickenson, AH; Kerr, NC; Reeve, AJ1
Akimoto, T; Mashimoto, S; Suetsugi, M; Ushijima, I; Watanabe, K; Yamada, M1
Gautier, H; Murariu, C1
Arnér, S1
Naghipour, B; Roushan-zamir, F; Shafaghi, B; Zarrindast, MR1
Hope, W; Salem, A1
Capasso, A1
Dixon, AK; Freeman, TC; Lee, K; Preston, Z; Richardson, PJ; Widdowson, L1
Bekkers, JM; Chieng, B1
Rao, VS; Santos, FA1
Christie, MJ; Hack, SP; Vaughan, CW1
Berglund, M; Eriksson, BE; Sadigh-Lindell, B; Sylvén, C2
Fathollahi, Y; Hajizadeh, S; Khorasani, MZ; Semnanian, S1
Antunes, C; Böhmer, AE; Elisabetsky, E; Lara, DR; Porciúncula, LO; Schallenberger, C; Schmidt, AP; Souza, DO1
Capasso, A; Gallo, C1
Baghdoyan, HA; Battersby, AS; Lydic, R; Nelson, AM1
Berdeaux, A; Chenoune, M; Cohen, MV; Darbera, L; Downey, JM; Ghaleh, B; Lidouren, F; Tissier, R1
Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J1
Batisti, AP; Brito, RN; Madeira, F; Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Stramosk, J; Turnes, BL1
Herrero, JF; Herrero-Zorita, C; Ramos-Zepeda, GA1
Bannister, K; Chen, Z; Dickenson, AH; Doyle, T; Ford, A; Jacobson, KA; Janes, K; Little, JW; Luongo, L; Maione, S; Porreca, F; Salvemini, D; Symons-Liguori, AM; Tosh, DK; Vanderah, TW; Xie, J1
Antkiewicz-Michaluk, L; Baranowska-Bosiacka, I; Chlubek, D; Fidecka, S; Gutowska, I; Listos, J; Listos, P; Orzelska-Górka, J; Pilutin, A; Talarek, S; Tarnowski, M; Tkacz, M; Wąsik, A; Łupina, M1

Reviews

3 review(s) available for adenosine and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
    NIDA research monograph, 1984, Volume: 54

    Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine

1984
[New aspects of the mechanism of the central nervous system stimulating effect of caffeine].
    Deutsche medizinische Wochenschrift (1946), 1984, Sep-28, Volume: 109, Issue:39

    Topics: Adenosine; Aminobutyrates; Animals; Brain; Caffeine; Calcium; Cyclic AMP; Habituation, Psychophysiologic; Humans; Mice; Naloxone; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Receptors, Purinergic; Xanthines

1984

Trials

3 trial(s) available for adenosine and naloxone

ArticleYear
Adenosine-provoked angina pectoris-like pain--time characteristics, influence of autonomic blockade and naloxone.
    European heart journal, 1987, Volume: 8, Issue:7

    Topics: Adenosine; Adrenergic beta-Antagonists; Adult; Angina Pectoris; Electrocardiography; Female; Heart Block; Humans; Male; Metoprolol; Naloxone; Receptors, Cholinergic; Receptors, Opioid; Receptors, Purinergic; Time Factors

1987
Role of adenosine and opioid-receptor mechanisms for pain in patients with silent myocardial ischemia or angina pectoris: a double-blind, placebo-controlled study.
    Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:6

    Topics: Adenosine; Angina Pectoris; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Time Factors

2003
High-dose adenosine infusion provokes oscillations of chest pain without correlation to opioid modulation: a double-blind controlled study.
    The journal of pain, 2004, Volume: 5, Issue:9

    Topics: Adenosine; Adult; Analgesics; beta-Endorphin; Chest Pain; Double-Blind Method; Humans; Male; Naloxone; Narcotic Antagonists; Periodicity

2004

Other Studies

61 other study(ies) available for adenosine and naloxone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Accumulation of adenosine 3',5'-monophosphate in rat brain slices: effects of prostaglandins.
    Life sciences, 1975, Jul-15, Volume: 17, Issue:2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Brain; Catecholamines; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; Hypothalamus; Isoproterenol; Male; Medulla Oblongata; Mesencephalon; Morphine; Naloxone; Phentolamine; Pons; Prostaglandin Antagonists; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Rats; Thalamus; Time Factors; Veratridine

1975
Is adenosine the mediator of opiate action on neuronal firing rate?
    Nature, 1979, Sep-20, Volume: 281, Issue:5728

    Topics: Action Potentials; Adenosine; Aminophylline; Animals; Corpus Striatum; Depression, Chemical; gamma-Aminobutyric Acid; Glutamates; Male; Morphine; Naloxone; Neural Inhibition; Neurons; Rats; Synaptic Transmission

1979
Opiate-dependent modulation of adenylate cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:8

    Topics: Adenosine; Adenylyl Cyclases; Cell Line; Cycloheximide; Enzyme Activation; Etorphine; Fluorides; Glioma; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Morphinans; Morphine; Naloxone; Neuroblastoma; Prostaglandins E

1977
Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:8

    Topics: Adenosine; Adenylyl Cyclases; Cell Division; Drug Tolerance; Humans; Hybrid Cells; Models, Biological; Morphine; Naloxone; Prostaglandins E; Substance-Related Disorders

1975
Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord.
    Neuroscience, 1992, Volume: 50, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Animals; Bicuculline; Cats; Evoked Potentials; Iontophoresis; Membrane Potentials; Naloxone; Neurons; Pain; Physical Stimulation; Purinergic Antagonists; Spinal Cord; Strychnine; Synapses; Theophylline; Vibration

1992
Effect of adenosine analogues on the expression of opiate withdrawal in rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:2

    Topics: Adenosine; Animals; Behavior, Animal; Clonidine; Diarrhea; Female; Male; Morphine Dependence; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1992
Effects of some adenosine analogs on morphine-induced analgesia and tolerance.
    General pharmacology, 1990, Volume: 21, Issue:5

    Topics: 2-Chloroadenosine; Adenosine; Analgesics; Animals; Caffeine; Drug Synergism; Drug Tolerance; Injections, Intraventricular; Mice; Morphine; Naloxone; Phenylisopropyladenosine

1990
Influence of adenosine analogs on morphine tolerance and dependence in mice.
    Cellular and molecular biology, 1990, Volume: 36, Issue:4

    Topics: Adenosine; Animals; Calcium; Drug Tolerance; Mice; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome

1990
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines

1986
Spinal antinociceptive effects of adenosine compounds in mice.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: Adenine Nucleotides; Adenosine; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Substance P; Theophylline

1987
Alpha 2-adrenergic, kappa-opiate, and P1-purinergic autoreceptors have mutually antagonistic effects: a new regulatory mechanism?
    Journal of neurochemistry, 1989, Volume: 53, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Caffeine; Calcium; Cerebral Cortex; Clonidine; Dioxanes; Fluorescent Dyes; Fura-2; Homeostasis; Idazoxan; Male; Naloxone; Phenylisopropyladenosine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Purinergic; Synaptosomes

1989
The effects of vasoactive intestinal peptide (VIP) antagonists, and VIP and peptide histidine isoleucine antisera on non-adrenergic, non-cholinergic relaxations of tracheal smooth muscle.
    British journal of pharmacology, 1989, Volume: 96, Issue:3

    Topics: Adenosine; Animals; Antibodies; Atropine; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Naloxone; Peptide PHI; Propranolol; Sympathectomy, Chemical; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide

1989
Role of endogenous adenosine in recurrent generalized seizures.
    Experimental neurology, 1989, Volume: 103, Issue:2

    Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Cats; Cerebral Cortex; Dipyridamole; Doxapram; Naloxone; Penicillins; Receptors, Purinergic; Reference Values; Seizures; Theophylline

1989
Inhibition of dopamine-sensitive adenylate cyclase by opioids: possible involvement of physically associated mu- and delta-opioid receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:3

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Corpus Striatum; Cyclic AMP; Dopamine Antagonists; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; In Vitro Techniques; Isoproterenol; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vasoactive Intestinal Peptide

1987
Central gastric antisecretory action of adenosine in the rat.
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anesthesia; Animals; Biogenic Amines; Brain Chemistry; Carbachol; Female; Gastric Mucosa; Gastrins; Indomethacin; Injections, Intraventricular; Male; Naloxone; Pylorus; Rats; Rats, Inbred Strains; Xanthines

1988
Development of tolerance to the inhibitory effects of ethanol in the isolated rat vas deferens. Effect of selective agonists and antagonists.
    Pharmacology, 1987, Volume: 34, Issue:6

    Topics: Adenosine; Animals; Drug Tolerance; Electric Stimulation; Ethanol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Phenoxybenzamine; Phentolamine; Rats; Rats, Inbred Strains; Vas Deferens

1987
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
    Neuroscience, 1987, Volume: 22, Issue:2

    Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration

1987
Dietary obesity: effects of drugs on food intake in S 5B/P1 and Osborne-Mendel rats.
    Physiology & behavior, 1985, Volume: 34, Issue:2

    Topics: Adenosine; Animals; Appetite; Body Weight; Deoxyglucose; Dextroamphetamine; Eating; Female; Glucose; Insulin; Naloxone; Rats; Rats, Inbred Strains

1985
Molecular mechanisms of opiate tolerance and dependence in a clonal cell line.
    NIDA research monograph, 1985, Volume: 62

    Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Line; Clone Cells; Cytosol; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Humans; Kinetics; Naloxone; Narcotics; Nerve Tissue Proteins; Substance-Related Disorders

1985
Inhibition by adenosine analogs of opiate withdrawal effects.
    NIDA research monograph, 1984, Volume: 49

    Topics: 2-Chloroadenosine; Adenosine; Animals; Behavior, Animal; Chlordiazepoxide; Guinea Pigs; Humans; Ileum; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Myenteric Plexus; Naloxone; Receptors, Cell Surface; Receptors, Purinergic; Substance Withdrawal Syndrome

1984
Neurotransmitters and biphasic respiratory response to hypoxia.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:1

    Topics: Adenosine; Aminophylline; Animals; Animals, Newborn; Endorphins; Hyperventilation; Hypoxia; Naloxone; Naltrexone; Neurotransmitter Agents; Phrenic Nerve; Respiration; Swine

1984
Coffee and opiate receptors. Another cup of coffee?
    Nature, 1983, Jan-20, Volume: 301, Issue:5897

    Topics: Adenosine; Animals; Caffeine; Coffee; Guinea Pigs; Humans; Naloxone; Receptors, Cell Surface; Receptors, Opioid; Receptors, Purinergic

1983
Attempted antagonism of adenosine analogue induced depression of respiration.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Animals, Newborn; Blood Gas Analysis; Brain Chemistry; Depression, Chemical; Dopamine; Female; Injections, Intraventricular; Male; Naloxone; Neurons; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Respiration; Serotonin

1984
Pharmacological profile of wet-dog shaking induced by electrical stimulation of the fornix in rats.
    Pharmacological research communications, 1984, Volume: 16, Issue:3

    Topics: Adenosine; Aminooxyacetic Acid; Animals; Atropine; Behavior, Animal; Dopamine; Electric Stimulation; Electrodes, Implanted; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Limbic System; Naloxone; Naltrexone; Neural Pathways; Physostigmine; Picrotoxin; Propranolol; Rats; Rats, Inbred Strains; Serotonin

1984
The effect of chronic morphine treatment of excitatory junction potentials in the mouse vas deferens.
    British journal of pharmacology, 1980, Volume: 68, Issue:3

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Morphine; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Naloxone; Vas Deferens

1980
Morphine enhances the release of 3H-purines from rat brain cerebral cortical prisms.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:4

    Topics: Adenosine; Animals; Cerebral Cortex; Evoked Potentials; Kinetics; Male; Morphine; Naloxone; Potassium Chloride; Purines; Rats; Rats, Inbred Strains; Tritium

1982
Effect of adenosine on carotid chemoreceptor activity in the cat.
    British journal of pharmacology, 1981, Volume: 74, Issue:1

    Topics: Adenosine; Aminophylline; Animals; Carotid Arteries; Cats; Chemoreceptor Cells; Electrophysiology; Female; Male; Naloxone; Theophylline

1981
Blockade of striatal neurone responses to morphine by aminophylline: evidence for adenosine mediation of opiate action.
    British journal of pharmacology, 1980, Volume: 69, Issue:1

    Topics: Adenosine; Aminophylline; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Male; Morphine; Naloxone; Neurons; Rats

1980
Morphine enhances adenosine release from the in vivo rat cerebral cortex.
    European journal of pharmacology, 1980, Jul-11, Volume: 65, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Cerebral Cortex; Male; Morphine; Naloxone; Rats; Time Factors

1980
Biochemical mechanisms of signalling pathways for different classes of analgesic molecules.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Adenosine; Analgesia; Analgesics; Animals; Guinea Pigs; Ileum; Methionine Adenosyltransferase; Models, Biological; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; S-Adenosylmethionine; Signal Transduction

1994
Adenosine and opiate-like substances mediates antinociception at the spinal cord.
    Brain research, 1995, Feb-27, Volume: 673, Issue:1

    Topics: Adenosine; Aminophylline; Animals; Female; Male; Morphine; Naloxone; Narcotics; Nociceptors; Rats; Rats, Wistar; Serotonin; Spinal Cord; Tail; Time Factors

1995
Adenosine A2 receptor regulation of apomorphine-induced turning in rats with unilateral striatal dopamine denervation.
    Psychopharmacology, 1993, Volume: 111, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Antihypertensive Agents; Apomorphine; Atropine; Brain; Dopamine; Female; Naloxone; Neostriatum; Oxidopamine; Phenethylamines; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrazines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical

1993
Morphine and norepinephrine-induced antinociception at the spinal level is mediated by adenosine.
    Neuroreport, 1994, Jul-21, Volume: 5, Issue:12

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminophylline; Animals; Female; Male; Morphine; Naloxone; Norepinephrine; Pain; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Serotonin; Spinal Cord; Time Factors

1994
Adenosine modulates the antinociceptive action of benzodiazepines.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Adenosine; Aminophylline; Analgesics; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Naloxone; Pain Measurement

1993
Effects of adenosine agonists and antagonists on pulmonary ventilation in conscious rats.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Bronchoconstriction; Bronchodilator Agents; Lung; Male; Naloxone; Narcotics; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Theophylline; Vasodilator Agents; Xanthines

1993
Selective changes of neurotransmitter receptors in middle-aged gerbil brain.
    Neurochemistry international, 1993, Volume: 23, Issue:6

    Topics: Adenosine; Aging; Animals; Autoradiography; Benzazepines; Brain; Dizocilpine Maleate; Gerbillinae; Isradipine; Male; Muscimol; Naloxone; Quinuclidinyl Benzilate; Receptors, Neurotransmitter; Tissue Distribution

1993
Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:12

    Topics: Adenosine; Analgesics; Animals; Dinoprostone; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Rats; Rats, Sprague-Dawley; Xanthines

1995
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2

    Topics: Adenosine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Dinoprostone; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Models, Biological; Naloxone; Narcotic Antagonists; Oligonucleotides, Antisense; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Receptors, Purinergic P1; Second Messenger Systems; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthines; Yohimbine

1997
Studies investigating the possible involvement of adenosine in the antisecretory action of morphine.
    General pharmacology, 1997, Volume: 28, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Decerebrate State; Female; Intestinal Mucosa; Jejunum; Male; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Reserpine; Sympatholytics; Vasoactive Intestinal Peptide; Xanthines

1997
Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist.
    Journal of neurophysiology, 1998, Volume: 79, Issue:3

    Topics: Adenosine; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Kynurenic Acid; Male; Morphine; Naloxone; Nerve Fibers; Neurons; Pain; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Touch

1998
Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1

    Topics: Adenosine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Caffeine; Carbamazepine; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Pain; Physical Stimulation; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Time Factors

1998
Neuromodulators and hypoxic hypothermia in the rat.
    Respiration physiology, 1998, Volume: 112, Issue:3

    Topics: Adenosine; Animals; Body Temperature; Carbon Monoxide; Hypothermia; Hypoxia; Male; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Theophylline

1998
Pain analysis in prediction of treatment outcome.
    Acta anaesthesiologica Scandinavica. Supplementum, 1998, Volume: 113

    Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Local; Dose-Response Relationship, Drug; Drug Administration Schedule; Forecasting; Humans; Infusions, Intravenous; Injections, Intravenous; Lidocaine; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Phentolamine; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympatholytics; Treatment Outcome

1998
Effects of adenosine receptor agents on the expression of morphine withdrawal in mice.
    European journal of pharmacology, 1999, Mar-12, Volume: 369, Issue:1

    Topics: Adenosine; Analysis of Variance; Animals; Behavior, Animal; Diarrhea; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Theobromine; Xanthines

1999
Role of endogenous adenosine in the expression of opiate withdrawal in rats.
    European journal of pharmacology, 1999, Mar-12, Volume: 369, Issue:1

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Hypoxanthine; Inosine; Male; Microdialysis; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome

1999
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
    Life sciences, 2000, Volume: 66, Issue:10

    Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline

2000
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines

2000
Inhibition of calcium channels by opioid- and adenosine-receptor agonists in neurons of the nucleus accumbens.
    British journal of pharmacology, 2001, Volume: 133, Issue:3

    Topics: Adenosine; Analgesics, Opioid; Animals; Barium; Calcium Channel Blockers; Calcium Channels; Cell Size; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Ethylmaleimide; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Interneurons; Ion Channel Gating; Naloxone; Narcotic Antagonists; Neostriatum; Neurons; Nucleus Accumbens; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Purinergic P1; Signal Transduction

2001
Possible role of mast cells in cineole-induced scratching behavior in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Cyclohexanols; Cyproheptadine; Diphenhydramine; Eucalyptol; Histamine H1 Antagonists; Male; Mast Cells; Mice; Monoterpenes; Naloxone; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Serotonin Antagonists; Terpenes; Theophylline

2002
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines

2003
Interaction of adenosine and naloxone on regional cerebral blood flow in morphine-dependent rats.
    Brain research, 2006, Apr-21, Volume: 1084, Issue:1

    Topics: Adenosine; Analgesics; Analysis of Variance; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Interactions; Laser-Doppler Flowmetry; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Regional Blood Flow

2006
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.
    British journal of pharmacology, 2009, Volume: 156, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Allopurinol; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamic Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrimidines; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines

2009
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
    Current drug safety, 2009, Volume: 4, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline

2009
Opioid-induced decreases in rat brain adenosine levels are reversed by inhibiting adenosine deaminase.
    Anesthesiology, 2009, Volume: 111, Issue:6

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Analgesics, Opioid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cognition; Male; Microdialysis; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reticular Formation; Sleep; Spectrophotometry, Ultraviolet

2009
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
    Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial Infarction; Naloxone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Opioid; Receptors, Purinergic P1; Theophylline; Time Factors

2012
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
    Neuroscience, 2013, Mar-27, Volume: 234

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines

2013
Peripheral neurobiologic mechanisms of antiallodynic effect of warm water immersion therapy on persistent inflammatory pain.
    Journal of neuroscience research, 2015, Volume: 93, Issue:1

    Topics: Adenosine; Animals; Benzoxazines; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Immersion; Indoles; Inflammation; Male; Mice; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Neurobiology; Pain Measurement; Receptor, Adenosine A1; Receptor, Cannabinoid, CB2; Receptors, Opioid; Water Purification

2015
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and κ-opioid receptors in rat spinal cord nociceptive reflexes.
    Behavioural pharmacology, 2014, Volume: 25, Issue:8

    Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Inflammation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord

2014
Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 1

    Topics: Adenosine; Animals; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Male; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Naloxone; Neuralgia; Neurons; Pain Measurement; Pain Threshold; Purinergic P1 Receptor Antagonists; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Spinal Cord; Time Factors

2015
The adenosinergic system is involved in sensitization to morphine withdrawal signs in rats-neurochemical and molecular basis in dopaminergic system.
    Psychopharmacology, 2016, Volume: 233, Issue:12

    Topics: Adenosine; Analgesics, Opioid; Animals; Behavior, Animal; Dopamine; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Dopamine; RNA, Messenger; Substance Withdrawal Syndrome

2016
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