5-hydroxy-2-n,n-dipropylaminotetralin and ropinirole
5-hydroxy-2-n,n-dipropylaminotetralin has been researched along with ropinirole in 3 studies
Compound Research Comparison
Studies (5-hydroxy-2-n,n-dipropylaminotetralin) | Trials (5-hydroxy-2-n,n-dipropylaminotetralin) | Recent Studies (post-2010) (5-hydroxy-2-n,n-dipropylaminotetralin) | Studies (ropinirole) | Trials (ropinirole) | Recent Studies (post-2010) (ropinirole) |
---|---|---|---|---|---|
42 | 0 | 3 | 637 | 129 | 243 |
Protein Interaction Comparison
Protein | Taxonomy | 5-hydroxy-2-n,n-dipropylaminotetralin (IC50) | ropinirole (IC50) |
---|---|---|---|
D(2) dopamine receptor | Bos taurus (cattle) | 6.81 |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Antonio, T; Dutta, AK; Ghosh, B; Kharkar, P; Reith, ME; Zhen, J | 1 |
Antonio, T; Dutta, AK; Ghosh, B; Reith, ME | 1 |
Antonio, T; Dutta, A; Ghosh, B; Gopishetty, B; Reith, M | 1 |
Other Studies
3 other study(ies) available for 5-hydroxy-2-n,n-dipropylaminotetralin and ropinirole
Article | Year |
---|---|
Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.
Topics: Animals; Antiparkinson Agents; Benzothiazoles; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Free Radical Scavengers; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoquinolines; Locomotion; Mice; Parkinson Disease; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Reserpine; Structure-Activity Relationship; Thiazoles | 2010 |
Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in sympto
Topics: Animals; Disease Models, Animal; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Iron Chelating Agents; Locomotion; Magnetic Resonance Spectroscopy; Male; Neuroprotective Agents; Oxyquinoline; Parkinson Disease; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Tetrahydronaphthalenes | 2010 |
Further delineation of hydrophobic binding sites in dopamine D(2)/D(3) receptors for N-4 substituents on the piperazine ring of the hybrid template 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol.
Topics: Binding Sites; Biphenyl Compounds; Cell Line; Humans; Hydrophobic and Hydrophilic Interactions; Piperazine; Piperazines; Receptors, Dopamine D2; Receptors, Dopamine D3; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes | 2010 |