Page last updated: 2024-09-27

Cone Dystrophy

A general term which describes a group of rare eye disorders that affect the cone cells of the RETINA. Cone dystrophy can cause a variety of symptoms including decreased visual clarity or acuity when looking straight ahead (central vision), a reduced ability to see colors, and an increased sensitivity to light (PHOTOPHOBIA).

Synonyms(3)

Synonym
Progressive Cone Dystrophy
Cone Dystrophy
Stationary Cone Dystrophy

Research

Studies (3)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's0 (0.00)28.8240
2020's3 (100.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
fomesafen0low10
11-cis-retinal0low10
cyclic gmp0low10

Protein Targets (17)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Retinaldehyde-binding protein 10011
Chain A, Retinaldehyde-binding protein 10011
Phosphodiesterase 0101
Multidrug resistance-associated protein 40001
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Luciferase1001
hypoxia-inducible factor 1 alpha subunit1001
progesterone receptor1001
estrogen-related nuclear receptor alpha1001
pregnane X nuclear receptor1001
estrogen nuclear receptor alpha1001
peroxisome proliferator activated receptor gamma1001
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
Histone H2A.x1001
nuclear factor erythroid 2-related factor 2 isoform 11001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]