A general term which describes a group of rare eye disorders that affect the cone cells of the RETINA. Cone dystrophy can cause a variety of symptoms including decreased visual clarity or acuity when looking straight ahead (central vision), a reduced ability to see colors, and an increased sensitivity to light (PHOTOPHOBIA).
Synonym |
---|
Progressive Cone Dystrophy |
Cone Dystrophy |
Stationary Cone Dystrophy |
Timeframe | Studies, This Condition (%) | All Conditions % |
---|---|---|
pre-1990 | 0 (0.00) | 23.3326 |
1990's | 0 (0.00) | 12.5806 |
2000's | 0 (0.00) | 18.1394 |
2010's | 0 (0.00) | 28.8240 |
2020's | 3 (100.00) | 9.53 |
Drug | Indicated | Relationship Strength | Studies | Trials |
---|---|---|---|---|
fomesafen | 0 | low | 1 | 0 |
11-cis-retinal | 0 | low | 1 | 0 |
cyclic gmp | 0 | low | 1 | 0 |
Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
---|---|---|---|---|
Chain A, Retinaldehyde-binding protein 1 | 0 | 0 | 1 | 1 |
Chain A, Retinaldehyde-binding protein 1 | 0 | 0 | 1 | 1 |
Phosphodiesterase | 0 | 1 | 0 | 1 |
Multidrug resistance-associated protein 4 | 0 | 0 | 0 | 1 |
Multidrug resistance-associated protein 5 | 0 | 0 | 0 | 1 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 0 | 1 | 0 | 1 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase A | 0 | 1 | 0 | 1 |
Luciferase | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
progesterone receptor | 1 | 0 | 0 | 1 |
estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
estrogen nuclear receptor alpha | 1 | 0 | 0 | 1 |
peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
Histone H2A.x | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |