| Assay ID | Title | Year | Journal | Article |
|---|
| AID192598 | Testes weight (treated)/body weight(treated)]/[testes weight(control)/body weight(control)] x 100 at a dose of 700 umol/kg/day | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID193263 | Percent efficacy (reduction in blood glucose) at 70 umol/kg in STZ diabetic rats after 11.25 days. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID194875 | Glucose levels were determined in an acute in vivo study for inhibition of gluconeogenesis in normal male Sprague-Dawley rats | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID192593 | Percent control of beta-hydroxybutyrate in normal 18 hr-fasted rat model dosed at 100 umol/Kg | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID193685 | Percent change in body weight in a 28-day safety study in normal Sprague-Dawley rats at 700 uM/kg/day. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID179672 | In vivo percentage efficacy, measured as ability to decrease blood glucose percentage after 11.25 days. | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID13519 | AUC was measured from the graph plotted against blood plasma concentration and time at the dose of 700 uMol/kg, | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID193264 | Percent efficacy (reduction in blood glucose) at 70 umol/kg in STZ diabetic rats after 8.25 days. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID193702 | Percent change in testes weight in a 28-day safety study in normal Sprague-Dawley rats at 700 uM/kg/day. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID25736 | Area under the curve was evaluated by plasma concentration and time curve in normal rat after oral dosing of 300 uM/kg | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID179673 | In vivo percentage efficacy, measured as ability to decrease blood glucose percentage after 8.25 days | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID192594 | Percent control of glucose in normal 18 hr-fasted rat model dosed at 100 umol/Kg | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID13518 | AUC was measured from the graph plotted against blood plasma concentration and time at the dose of 300 uMol/kg, | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID193696 | Percent change in liver weight in a 28-day safety study in normal Sprague-Dawley rats at 700 uM/kg/day. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| AID192592 | Ketone levels were determined in an acute in vivo study for inhibition of gluconeogenesis in normal male Sprague-Dawley rats | 1999 | Journal of medicinal chemistry, Jan-14, Volume: 42, Issue:1
| Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid. |
| AID193691 | Percent change in heart weight in a28-day safety study in normal Sprague-Dawley rats at 700 uM/kg/day. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Reduction in glucose levels in STZ diabetic rats by 4-(2,2-dimethyl-1-oxopropyl)benzoic acid: a prodrug approach for targeting the liver. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |