Page last updated: 2024-11-05
n-butyltin
n-Butyltin compounds, also known as tributyltin (TBT), are organotin compounds with the general formula Sn(C4H9)n, where n = 1-4. They are synthetically produced by reacting tin with butyl chloride in the presence of a catalyst. These compounds have been widely used as antifouling agents in paints, plastics, and other materials to prevent the growth of marine organisms on surfaces. However, TBT has been found to have severe toxic effects on marine life, particularly on shellfish, causing reproductive problems and shell deformation. Due to its detrimental environmental impact, the use of TBT in antifouling paints has been banned in many countries. Research on n-butyltin focuses on understanding its environmental fate and toxicity, developing alternative antifouling agents, and studying its bioaccumulation in organisms. '
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 16996 |
| CHEBI ID | 22966 |
| MeSH ID | M0172058 |
Synonyms (14)
| Synonym |
|---|
| butyltin |
| sn(bu)h3 |
| [sn(bu)h3] |
| CHEBI:22966 |
| butylstannane |
| stannane, butyl- |
| butyltin trihydride |
| n-butyltin |
| tin, butyltrihydro- |
| 2406-65-7 |
| monobutyltin hydride |
| butyltin hydride |
| DTXSID20904117 |
| Q27109618 |
Drug Classes (1)
| Class | Description |
|---|
| organotin compound | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (16)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 11 (68.75) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.11
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.11 (24.57) | | Research Supply Index | 2.94 (2.92) | | Research Growth Index | 5.05 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 18 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |