Compounds > mirabilin
Page last updated: 2024-11-13

mirabilin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

mirabilin: isolated from tubers of Cyclamen mirabile; mirabilin G (an alkaloid) is also available; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
CyclamengenusA plant genus of the family PRIMULACEAE that contains triterpenoid saponins.[MeSH]PrimulaceaeA plant family of the order ERICALES, class MAGNOLIOPSIDA, with flowers having both stamens and pistil, producing encapsulated fruits.[MeSH]

Cross-References

ID SourceID
PubMed CID44566610
CHEMBL ID499264
MeSH IDM0275520

Synonyms (2)

Synonym
mirabilin
CHEMBL499264
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID402882Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by microtiter-tube dilution method1997Journal of natural products, Mar, Volume: 60, Issue:3
Triterpene saponins from Cyclamen mirabile and their biological activities.
AID402894Uterocontractile activity in rat uterus assessed as contraction at 6.4 uM relative to acetylcholine1997Journal of natural products, Mar, Volume: 60, Issue:3
Triterpene saponins from Cyclamen mirabile and their biological activities.
AID402879Antibacterial activity against Staphylococcus aureus ATCC 29213 by microtiter-tube dilution method1997Journal of natural products, Mar, Volume: 60, Issue:3
Triterpene saponins from Cyclamen mirabile and their biological activities.
AID402881Antibacterial activity against Escherichia coli ATCC 25922 by microtiter-tube dilution method1997Journal of natural products, Mar, Volume: 60, Issue:3
Triterpene saponins from Cyclamen mirabile and their biological activities.
AID402880Antibacterial activity against Enterococcus faecalis ATCC 29212 by microtiter-tube dilution method1997Journal of natural products, Mar, Volume: 60, Issue:3
Triterpene saponins from Cyclamen mirabile and their biological activities.
AID402896Uterocontractile activity in rat uterus assessed as contraction at 19 uM relative to acetylcholine1997Journal of natural products, Mar, Volume: 60, Issue:3
Triterpene saponins from Cyclamen mirabile and their biological activities.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 18.06

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index18.06 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (18.06)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
guanidine
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.. guanidine : An aminocarboxamidine, the parent compound of the guanidines.		2.110carboxamidine;
guanidines;
one-carbon compound
quinazolines
Quinazolines: A group of aromatic heterocyclic compounds that contain a bicyclic structure with two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring.. quinazoline : A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.. quinazolines : Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives.		2.0410azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
oleanolic acid
[no description available]		3.1350hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
cyclamin
cyclamin: antineoplastic from Ardisia japonica; structure in first source		1.9910triterpenoid
beta-escin
[no description available]		3.1350
ConditionIndicatedRelationship StrengthStudiesTrials