Compounds > l 11204
Page last updated: 2024-12-07

l 11204

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

L 11204: antifertility agent in vivo; inhibitor of prostaglandin synthesis; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID119282
SCHEMBL ID11414889
MeSH IDM0063822

Synonyms (25)

Synonym
ll-11204
dl-204-it
2-(3-ethoxyphenyl)-5,6-dihydro-s-triazolo(5,1-a)isoquinoline
l-11204
dl 204it
dl 204
brn 0892393
2-(3-ethoxyphenyl)-5,6-dihydro-(1,2,4)triazolo(5,1-a)isoquinoline
(1,2,4)triazolo(5,1-a)isoquinoline, 2-(3-ethoxyphenyl)-5,6-dihydro-
5,6-dihydro-2-(3-ethoxyphenyl)-s-triazolo(5,1-a)isoquinoline
s-triazolo(5,1-a)isoquinoline, 5,6-dihydro-2-(m-ethoxyphenyl)-
2-(3-ethoxyphenyl)-5,6-dihydro-s-triazole(5,1-a)isoquinoline
dl-204 ,
l 11204
dl 204-it
2-(3-ethoxyphenyl)-5,6-dihydro[1,2,4]triazolo[5,1-a]isoquinoline
55308-64-0
2-(3-ethoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-a]isoquinoline
NZDDMKIDRQAGND-UHFFFAOYSA-N
2-(3-ethoxyphenyl)-5,6-dihydro-s-triazolo[5,1-a]isoquinoline
SCHEMBL11414889
DTXSID30203860
[1,2,4]triazolo[5,1-a]isoquinoline, 2-(3-ethoxyphenyl)-5,6-dihydro-
P5KT3ZA5PD
AKOS040745959

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Most of the members of these series of compounds are effective with a single injection although the dosage can be 5 or more times as large as that needed for each of 5 daily injections."( Development of novel embryotoxic compounds for interceptive fertility control in the dog.
Lerner, LJ, 1989)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.15

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.15 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.15)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.		2.37201,2,3-triazole
l 10503
[no description available]		1.9710
dl 111-it
3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole: non-hormonal antifertility agent; RN & N1 from CA Vol 90		1.9710
contraceptives, postcoital
Contraceptives, Postcoital: Contraceptive substances to be used after COITUS. These agents include high doses of estrogenic drugs; progesterone-receptor blockers; ANTIMETABOLITES; ALKALOIDS, and PROSTAGLANDINS.		1.9610
hyaluronoglucosaminidase
Hyaluronoglucosaminidase: An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		03.2160
Fetal Resorption
The disintegration and assimilation of the dead FETUS in the UTERUS at any stage after the completion of organogenesis which, in humans, is after the 9th week of GESTATION. It does not include embryo resorption (see EMBRYO LOSS).		01.9610
Endometrial Diseases
[description not available]		01.9610
Uterine Diseases
Pathological processes involving any part of the UTERUS.		01.9610
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.		01.9710