Page last updated: 2024-10-15

inp 0341

Description

INP 0341: a salicylidene acylhydrazide that inhibits the type III secretion system and inhibits Chlamydia growth [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	135874511
MeSH ID	M0536622

Synonyms (8)

Synonym
n-[(e)-(5-chloro-2-hydroxy-3-methyl-phenyl)methyleneamino]-2,4-dihydroxy-benzamide
inp 0341
benzoic acid, 2,4-dihydroxy-, 2-((5-chloro-2-hydroxy-3-methylphenyl)methylene)hydrazide
1929611-92-6
me 0329
unii-62dd8ff6gm
n'-(5-chloro-2-hydroxy-3-methylbenzylidene)-2,4-dihydroxybenzhydrazide
62dd8ff6gm ,

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (12.50)	29.6817
2010's	6 (75.00)	24.3611
2020's	1 (12.50)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
hydrazine diamine : Any polyamine that contains two amino groups.	3.6	8	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
chiniofon Hydroxyquinolines: The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.	2.15	1
heme Heme: The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.. ferroheme : Any iron(II)--porphyrin coordination complex.. ferroheme b : Heme b in which the iron has oxidation state +2.. heme : A heme is any tetrapyrrolic chelate of iron.	2.08	1

Condition	Relationship Strength	Studies
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.8	3
Infections, Pseudomonas [description not available]	2.59	2
Keratitis Inflammation of the cornea.	2.25	1
Pseudomonas Infections Infections with bacteria of the genus PSEUDOMONAS.	2.59	2
Infection, Wound [description not available]	2.15	1
Burns Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.	2.15	1
Lymphogranuloma Inguinale [description not available]	2.1	1
Infections, Chlamydia [description not available]	2.75	3
Chlamydia Infections Infections with bacteria of the genus CHLAMYDIA.	2.75	3
Neisseria gonorrhoeae Infection [description not available]	2.05	1
Gonorrhea Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.	2.05	1

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