Page last updated: 2024-11-06

2,3-dibromo-1,4-naphthoquinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,3-dibromo-1,4-naphthoquinone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID83259
CHEMBL ID1989145
SCHEMBL ID1240837
MeSH IDM0581817

Synonyms (37)

Synonym
nsc-618332
NSC618332 ,
NCI60_005561
NCIMECH_000534
nsc106320
1, 2,3-dibromo-
13243-65-7
nsc-106320
1,4-naphthalenedione, 2,3-dibromo-
inchi=1/c10h4br2o2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4
2,3-dibromonaphthoquinone
2,3-dibromo-1,4-naphthoquinone, 97%
NCI60_000148
2,3-dibromonaphthalene-1,4-dione
2,3-dibromo-1,4-naphthoquinone
nsc 106320
1,4-naphthoquinone, 2,3-dibromo-
einecs 236-223-7
CCG-35639
FT-0636853
10.14272/PSMABVOYZJWFBV-UHFFFAOYSA-N
doi:10.14272/psmabvoyzjwfbv-uhfffaoysa-n
AKOS015912948
CHEMBL1989145
STL323127
PSMABVOYZJWFBV-UHFFFAOYSA-N
SCHEMBL1240837
DTXSID20157580
AS-62043
CS-0132862
J-006177
2,3-dibromo-1,4-dihydronaphthalene-1,4-dione
F0433-0200
doi:10.14272/psmabvoyzjwfbv-uhfffaoysa-n.1
10.14272/PSMABVOYZJWFBV-UHFFFAOYSA-N.1
2,3-dibrom-1,4-naphthochinon
PD011877
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID672420Inhibition of Mycobacterium tuberculosis C-terminal His6-tagged MetAP1A using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Co2+2012Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.
AID672426Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 2 weeks2012Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.
AID672423Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged MetAP1C using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Mn2+2012Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.
AID672422Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged MetAP1C using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Co2+2012Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.
AID672421Inhibition of Mycobacterium tuberculosis C-terminal His6-tagged MetAP1A using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Mn2+2012Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.72 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]