Page last updated: 2024-12-07
2,3-dibromo-1,4-naphthoquinone
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
2,3-dibromo-1,4-naphthoquinone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 83259 |
| CHEMBL ID | 1989145 |
| SCHEMBL ID | 1240837 |
| MeSH ID | M0581817 |
Synonyms (37)
| Synonym |
|---|
| nsc-618332 |
| NSC618332 , |
| NCI60_005561 |
| NCIMECH_000534 |
| nsc106320 |
| 1, 2,3-dibromo- |
| 13243-65-7 |
| nsc-106320 |
| 1,4-naphthalenedione, 2,3-dibromo- |
| inchi=1/c10h4br2o2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4 |
| 2,3-dibromonaphthoquinone |
| 2,3-dibromo-1,4-naphthoquinone, 97% |
| NCI60_000148 |
| 2,3-dibromonaphthalene-1,4-dione |
| 2,3-dibromo-1,4-naphthoquinone |
| nsc 106320 |
| 1,4-naphthoquinone, 2,3-dibromo- |
| einecs 236-223-7 |
| CCG-35639 |
| FT-0636853 |
| 10.14272/PSMABVOYZJWFBV-UHFFFAOYSA-N |
| doi:10.14272/psmabvoyzjwfbv-uhfffaoysa-n |
| AKOS015912948 |
| CHEMBL1989145 |
| STL323127 |
| PSMABVOYZJWFBV-UHFFFAOYSA-N |
| SCHEMBL1240837 |
| DTXSID20157580 |
| AS-62043 |
| CS-0132862 |
| J-006177 |
| 2,3-dibromo-1,4-dihydronaphthalene-1,4-dione |
| F0433-0200 |
| doi:10.14272/psmabvoyzjwfbv-uhfffaoysa-n.1 |
| 10.14272/PSMABVOYZJWFBV-UHFFFAOYSA-N.1 |
| 2,3-dibrom-1,4-naphthochinon |
| PD011877 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID672420 | Inhibition of Mycobacterium tuberculosis C-terminal His6-tagged MetAP1A using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Co2+ | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14 | Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. |
| AID672426 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 2 weeks | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14 | Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. |
| AID672423 | Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged MetAP1C using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Mn2+ | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14 | Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. |
| AID672422 | Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged MetAP1C using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Co2+ | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14 | Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. |
| AID672421 | Inhibition of Mycobacterium tuberculosis C-terminal His6-tagged MetAP1A using methionylprolyl-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition measured for 20 mins by spectrophotometry in presence of Mn2+ | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14 | Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.72
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.72) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||