Compounds > allyl methyl disulfide
Page last updated: 2024-12-06

allyl methyl disulfide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Allyl methyl disulfide is a sulfur-containing organic compound with the formula CH2=CHCH2SSCH3. It is a colorless liquid with a pungent garlic-like odor. It is a naturally occurring compound found in garlic and other alliums. It has been reported to have a number of biological effects, including antimicrobial, anti-inflammatory, and antioxidant properties. Allyl methyl disulfide has also been shown to have anticancer effects in some studies. The compound is thought to exert its effects through its ability to react with cellular components, such as proteins and enzymes, and to modulate signaling pathways. Allyl methyl disulfide is a subject of ongoing research due to its potential therapeutic applications. Studies are being conducted to evaluate its efficacy in treating a range of conditions, including cancer, infections, and cardiovascular disease.'

allyl methyl disulfide: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

allyl methyl disulfide : An organic disulfide having allyl and methyl as the two organic groups. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID62434
CHEBI ID6854
SCHEMBL ID548935
SCHEMBL ID9535067
MeSH IDM0153916

Synonyms (40)

Synonym
3-(methyldisulfanyl)-1-propene
disulfide, methyl 2-propenyl
CHEBI:6854
3-(methyldisulfanyl)prop-1-ene
3-(methyldithio)prop-1-ene
methyl 2-propenyl disulfide
methylallyl disulphide
4,5-dithia-1-hexene
allyl methyl disulphide
C08383
allyl methyl disulfide
2179-58-0
methyl allyl disulfide
AKOS006344179
A815666
oxw45utr7b ,
ccris 3266
einecs 218-549-1
unii-oxw45utr7b
disulfide, allyl methyl
fema no. 3127
FT-0634100
SCHEMBL548935
allyl methyl disulfide [fhfi]
disulfide, methyl-2-propenyl
SCHEMBL9535067
mfcd00040023
XNZOTQPMYMCTBZ-UHFFFAOYSA-N
3-(methyldisulfanyl)-1-propene #
2-propenylmethyldisulfide
DTXSID60176199
fema 3127
CS-0204953
1-allyl-2-methyldisulfane
Q27107347
D88486
allylmethyldisulfide
BS-44089
?methyl allylic ii sulfur ether
EN300-1610756

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
volatile oil componentAny plant metabolite that is found naturally as a component of a volatile oil.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
organic disulfideCompounds of structure RSSR in which R and R' are organic groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.85

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.85 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.85)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetaminophen
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.. paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.		7.1310acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
benzo(a)pyrene
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.. benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.		1.9710ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
allyl sulfide
allyl sulfide: essence of garlic; inhibits CYP2E1		2.3820organic sulfide
diallyl trisulfide
[no description available]		2.3920organic trisulfideanti-inflammatory agent;
antilipemic drug;
antineoplastic agent;
antioxidant;
antiprotozoal drug;
apoptosis inducer;
estrogen receptor antagonist;
insecticide;
platelet aggregation inhibitor;
vasodilator agent
diallyl disulfide
diallyl disulfide: major constituent of garlic oil. diallyl disulfide : An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus Allium.		2.110organic disulfideantifungal agent;
antineoplastic agent;
plant metabolite
dimethyl trisulfide
[no description available]		2.0610organic trisulfide
di-n-propyl trisulfide
di-n-propyl trisulfide: antioxidant found in Allium species; structure in first source		2.0610organic trisulfide
methylallyl trisulfide
methylallyl trisulfide: platelet aggregation inhibitor in garlic		2.420
allyl methyl sulfide
[no description available]		2.110organic sulfide
sulfur
Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.		2.110chalcogen;
nonmetal atom		macronutrient
ConditionIndicatedRelationship StrengthStudiesTrials
Halitosis
An offensive, foul breath odor resulting from a variety of causes such as poor oral hygiene, dental or oral infections, or the ingestion of certain foods.		02.110
Innate Inflammatory Response
[description not available]		02.1110
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.		02.1110
Acute Liver Injury, Drug-Induced
[description not available]		02.1310
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.		02.1310
Acantholysis
Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.		01.9810
Bleb
[description not available]		01.9810
Pemphigus Foliaceus
[description not available]		01.9810
Pemphigus
Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.		01.9810
Cancer of Lung
[description not available]		01.9710
Cancer of Stomach
[description not available]		01.9710
Lung Neoplasms
Tumors or cancer of the LUNG.		01.9710
Stomach Neoplasms
Tumors or cancer of the STOMACH.		01.9710