Compounds > epinephrine sulfate
Page last updated: 2024-12-10

epinephrine sulfate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID3035453
CHEBI ID89878
MeSH IDM0111193

Synonyms (21)

Synonym
epinephrine sulfate
[2-hydroxy-4-[(1r)-1-hydroxy-2-(methylamino)ethyl]phenyl] hydrogen sulfate
unii-cm4ibp5llv
cm4ibp5llv ,
77469-50-2
epinephrine-3-o-sulfate
1,2-benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, mono(hydrogen sulfate) (ester), (r)-
unii-t074675s0e
epinephrine 4-sulfate
85927-06-6
2-hydroxy-4-((1r)-1-hydroxy-2-(methylamino)ethyl)phenyl hydrogen sulfate
epinephrine 4-o-sulfate
T074675S0E ,
adrenaline sulphate
1,2-benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, 1-(hydrogen sulfate), (r)-
(r)-4-(1-hydroxy-2-(methylamino)ethyl)-2-benzenediol mono(hydrogen sulfate) (ester)
{2-hydroxy-4-[(1r)-1-hydroxy-2-(methylamino)ethyl]phenyl}oxidanesulfonic acid
CHEBI:89878
(r)-4-[1-hydroxy-2-(methylamino)ethyl]-2-benzenediol mono(hydrogen sulfate) (ester)
(r)-4-[1-hydroxy-2-(methylamino)ethyl]-2-benzenediol mono(hydrogen sulphate) (ester)
Q27162062
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
catecholamine4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-199012 (63.16)18.7374
1990's7 (36.84)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.88

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.88 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.88)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.76%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (95.24%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
homovanillic acid
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.. homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.. homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.		1.9610guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
dopamine 3-o-sulfate
dopamine 3-O-sulfate: end product of L-Dopa metabolism in Parkinson patients; see also record for dopamine 4-O-sulfate. dopamine 3-O-sulfate : An aryl sulfate that is dopamine in which the phenolic hydrogen at position 3 has been replaced by a sulfo group.		2.8940aryl sulfate;
phenols;
primary amino compound;
zwitterion		human blood serum metabolite;
human urinary metabolite
noradrenaline sulfate
[no description available]		4.22180catecholamine
dopamine 4-o-sulfate
dopamine 4-O-sulfate: possible precursor of free norepinephrin; see also record for dopamine 3-O-sulfate. dopamine 4-O-sulfate : An aryl sulfate that is dopamine in which the phenolic hydrogen at position 4 has been replaced by a sulfo group.		3.84120aryl sulfate;
phenols;
primary amino compound;
zwitterion		human blood serum metabolite;
human urinary metabolite
cocaine
Cocaine: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.. cocaine : A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.		1.9810benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
dopamine glucuronide
dopamine glucuronide: metabolite of dopamine		2.3720glucosiduronic acid
ConditionIndicatedRelationship StrengthStudiesTrials
Chemical Dependence
[description not available]		01.9810
Substance-Related Disorders
Disorders related to substance use or abuse.		01.9810
Adrenal Cancer
[description not available]		01.9710
Pheochromocytoma, Extra-Adrenal
[description not available]		01.9710
Pheochromocytoma
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)		01.9710
Behavior Disorders
[description not available]		01.9710
Fasting Hypoglycemia
HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.		01.9710
Mental Disorders
Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.		01.9710
Hypoglycemia
A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.		01.9710