vitamin transmembrane transporter activity
Definition
Target type: molecularfunction
Enables the transfer of a vitamin from one side of a membrane to the other. [GOC:tb]
Vitamin transmembrane transporter activity is a fundamental process in cellular physiology, facilitating the movement of vitamins across cell membranes. These transporters are highly selective proteins that bind specific vitamin molecules and mediate their passage through the lipid bilayer. This activity plays a critical role in the uptake and distribution of essential vitamins, ensuring adequate levels for various metabolic processes. Vitamin transmembrane transporters exhibit diverse mechanisms, ranging from passive diffusion to active transport, often involving conformational changes to bind and release vitamin molecules. The specific transporter involved dictates the direction of transport, whether from the extracellular environment into the cell (uptake) or from the intracellular compartment to the extracellular space (efflux). The activity of these transporters is crucial for maintaining homeostasis of vitamin levels, preventing deficiencies, and supporting vital functions, including energy production, cell growth, and immune responses.'
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Proteins (1)
Protein | Definition | Taxonomy |
---|---|---|
Vitamin D-binding protein | A vitamin D-binding protein that is encoded in the genome of human. [PRO:DNx, UniProtKB:P02774] | Homo sapiens (human) |
Compounds (1)
Compound | Definition | Classes | Roles |
---|---|---|---|
calcitriol | dihydroxy-vitamin D3: as a major in vitro metabolite of 1alpha,25-dihydroxyvitamin D3, produced in primary cultures of neonatal human keratinocytes | D3 vitamins; hydroxycalciol; triol | antineoplastic agent; antipsoriatic; bone density conservation agent; calcium channel agonist; calcium channel modulator; hormone; human metabolite; immunomodulator; metabolite; mouse metabolite; nutraceutical |