alkali metal ion binding

Definition

Target type: molecularfunction

Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen. [GOC:mah]

Alkali metal ion binding is a molecular function that involves the interaction of a protein or other molecule with an alkali metal ion, such as lithium (Li+), sodium (Na+), potassium (K+), rubidium (Rb+), or cesium (Cs+). These ions are essential for a wide range of biological processes, including nerve impulse transmission, muscle contraction, and maintaining fluid balance. The binding of alkali metal ions to proteins is typically mediated by specific amino acid residues, such as aspartate, glutamate, and lysine. These residues form electrostatic interactions with the positively charged alkali metal ions, creating a stable binding site. The affinity of a protein for an alkali metal ion can be influenced by factors such as the size and charge of the ion, the surrounding environment, and the presence of other ligands. Alkali metal ion binding can also be regulated by changes in pH, temperature, and the concentration of other ions. The specific interactions between alkali metal ions and proteins are crucial for the proper functioning of many cellular processes. Mutations or disruptions in these interactions can lead to various diseases, including heart disease, neurological disorders, and metabolic disorders.'
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Proteins (1)

Compounds (2)