Page last updated: 2024-10-24
dihydropyrimidine dehydrogenase (NADP+) activity
Definition
Target type: molecularfunction
Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+. [EC:1.3.1.2]
Proteins (1)
| Protein | Definition | Taxonomy |
|---|---|---|
| Dihydropyrimidine dehydrogenase [NADP(+)] | A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q12882] | Homo sapiens (human) |
Compounds (4)
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| eniluracil | eniluracil: structure in first source; inactivates dihydropyrimidine dehydrogenase | pyrimidone | |
| 5-iodouracil | 5-iodouracil : An organoiodine compound consisting of uracil having an iodo substituent at the 5-position. 5-iodouracil: RN given refers to parent cpd | organoiodine compound | antimetabolite |
| 5-cyanouracil | |||
| 5-vinyluracil | 5-vinyluracil: RN given refers to unlabeled parent cpd |