sialic acid:proton symporter activity

Definition

Target type: molecularfunction

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in). [TC:2.A.1.12.1]

Sialic acid:proton symporter activity refers to the transmembrane protein that facilitates the simultaneous movement of sialic acid and protons (H+) across a cell membrane. This process is driven by the electrochemical gradient of protons, meaning that the energy stored in the difference in proton concentration across the membrane is used to drive the transport of sialic acid. The symporter works by binding both sialic acid and a proton on one side of the membrane. This binding event triggers a conformational change in the protein, allowing the molecules to move across the membrane and be released on the other side. Sialic acid:proton symporters are essential for the uptake of sialic acid, which is a crucial component of glycoproteins and glycolipids found in the cell membrane. These molecules play important roles in cell signaling, adhesion, and immune recognition. The symporters help maintain appropriate levels of sialic acid within cells, which is crucial for proper cell function and development.'
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Proteins (2)

Compounds (2)