Target type: molecularfunction
Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms. [GOC:ai]
Myo-inositol transmembrane transporter activity refers to the ability of a protein to facilitate the movement of myo-inositol across cell membranes. Myo-inositol is a sugar alcohol that plays a crucial role in various cellular processes, including signal transduction, cell growth, and membrane integrity. These transporters function by binding myo-inositol on one side of the membrane and facilitating its passage to the other side, often against its concentration gradient. This transport is typically driven by energy derived from ATP hydrolysis or electrochemical gradients. The myo-inositol transmembrane transporter activity is essential for maintaining proper levels of myo-inositol within cells, ensuring proper function of various signaling pathways and cellular processes.'
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| Protein | Definition | Taxonomy |
|---|---|---|
| Sodium/myo-inositol cotransporter 2 | A sodium/myo-inositol cotransporter 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8WWX8] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| inositol | 1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction. inositol : Any cyclohexane-1,2,3,4,5,6-hexol. Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction. muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration. | cyclitol; hexol | |
| dapagliflozin | aromatic ether; C-glycosyl compound; monochlorobenzenes | hypoglycemic agent; sodium-glucose transport protein subtype 2 inhibitor |