organic acid transmembrane transporter activity

Definition

Target type: molecularfunction

Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage. [ISBN:0198506732]

Organic acid transmembrane transporter activity involves the movement of organic acids across cellular membranes. This process is essential for various physiological functions, including:

* **Nutrient uptake:** Organic acids like lactate, pyruvate, and citrate are crucial energy sources for cells. Transporters facilitate their uptake, ensuring energy supply.
* **Waste product removal:** Organic acid waste products, such as lactate from muscle activity, are exported from cells through transporters, preventing buildup and maintaining homeostasis.
* **Metabolic regulation:** Transporters play a role in regulating metabolic pathways by controlling the flux of organic acids between different cellular compartments.
* **pH regulation:** Some organic acid transporters contribute to maintaining intracellular pH by exchanging organic acids with protons.

The mechanism of transport can vary depending on the specific transporter and the organic acid involved. Some transporters utilize passive diffusion, while others employ active transport mechanisms driven by ATP hydrolysis or coupled to the movement of other ions.

Organic acid transmembrane transporter activity is crucial for maintaining cellular function and overall organismal health. Dysregulation of these transporters can lead to various metabolic disorders and diseases.'
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Proteins (1)

Compounds (1)