Golgi medial cisterna membrane

Definition

Target type: cellularcomponent

The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex. [GOC:bhm, PMID:16038056, PMID:24119662]

The Golgi medial cisterna membrane is a specialized subcompartment of the Golgi apparatus, a key organelle in eukaryotic cells. It is positioned between the cis and trans cisternae, playing a critical role in protein modification and sorting. This membrane is characterized by its unique protein composition, which includes enzymes involved in glycosylation, phosphorylation, and sulfation of proteins as they traverse the Golgi. It also contains transport proteins that mediate the movement of proteins between cisternae. The Golgi medial cisterna membrane is physically continuous with the membranes of other Golgi cisternae, forming a dynamic network of interconnected compartments. This connectivity facilitates the efficient and regulated transport of cargo proteins through the Golgi pathway. The membrane itself is comprised of a phospholipid bilayer, similar to other cellular membranes, but its specific lipid composition contributes to its distinctive properties. The Golgi medial cisterna membrane is highly enriched in specific phospholipids, including phosphatidylinositol and phosphatidylserine, which may be involved in the recruitment and localization of proteins. In addition to its role in protein processing, the Golgi medial cisterna membrane is also involved in the synthesis of glycosphingolipids, important components of cellular membranes, and in the formation of transport vesicles that bud off from the Golgi and deliver their cargo to other cellular destinations.'
"

Proteins (1)

Compounds (11)