flavin adenine dinucleotide catabolic process
Definition
Target type: biologicalprocess
The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. [GOC:mah]
The flavin adenine dinucleotide (FAD) catabolic process is a series of biochemical reactions that break down FAD into its constituent components: riboflavin, adenine, and phosphate. This process occurs in various organisms and is crucial for the recycling of riboflavin, a vital component of several essential enzymes.
The process initiates with the hydrolysis of FAD into FMN (flavin mononucleotide) and AMP (adenosine monophosphate) catalyzed by the enzyme FAD pyrophosphatase. FMN can then be further hydrolyzed into riboflavin and phosphate by FMN hydrolase.
In some organisms, the breakdown of FAD can also occur through alternative pathways. For example, in certain bacteria, FAD can be directly converted to riboflavin by a specific enzyme, FAD reductase.
The catabolic process of FAD is tightly regulated, ensuring the efficient utilization of riboflavin and the maintenance of cellular energy metabolism. The breakdown products of FAD, riboflavin and phosphate, can be reused for the synthesis of new FAD or other essential molecules. Riboflavin, the vitamin B2, is essential for numerous cellular processes, including energy production, DNA synthesis, and cell growth. Its recycling through the FAD catabolic process is crucial for maintaining cellular health and function.'
"
Proteins (1)
| Protein | Definition | Taxonomy |
|---|---|---|
| Transitional endoplasmic reticulum ATPase | A transitional endoplasmic reticulum ATPase that is encoded in the genome of human. [PRO:DNx, UniProtKB:P55072] | Homo sapiens (human) |
Compounds (6)
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| clotrimazole | conazole antifungal drug; imidazole antifungal drug; imidazoles; monochlorobenzenes | antiinfective agent; environmental contaminant; xenobiotic | |
| Methylenedioxycinnamic acid | hydroxycinnamic acid | ||
| 3,4-methylenedioxy-beta-nitrostyrene | 3,4-methylenedioxy-beta-nitrostyrene: tyrosine kinase inhibitor that prevents platelet glycoprotein IIb/IIIa activation; structure in first source | ||
| 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol | substituted aniline | ||
| ML240 | ML240 : A member of the class of quinazolines that is quinazoline which is substituted at positions 2, 5 and 8 by 2-amino-1H-benzimidazol-1-yl, benzylnitrilo and methoxy groups, respectively. It is a ATP-competetive inhibitor of AAA ATPase p97, also known as valosin-containing protein (VCP). | aromatic amine; aromatic ether; benzimidazoles; primary amino compound; quinazolines; secondary amino compound | antineoplastic agent |
| ganciclovir | 2-aminopurines; oxopurine | antiinfective agent; antiviral drug |