Target type: biologicalprocess
The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP. [GOC:dph, ISBN:0201090910]
The glycolytic process from galactose, also known as galactose metabolism, is a complex pathway involving multiple steps and enzymes to convert galactose, a simple sugar found in milk and other dairy products, into glucose, a primary energy source for the body. This pathway begins with the phosphorylation of galactose by galactokinase to form galactose-1-phosphate. Galactose-1-phosphate is then converted to glucose-1-phosphate by the enzyme galactose-1-phosphate uridyltransferase (GALT). This step is crucial for the pathway, and deficiency in GALT can lead to the genetic disorder galactosemia. Glucose-1-phosphate is then isomerized to glucose-6-phosphate, a key intermediate in both glycolysis and gluconeogenesis. Glucose-6-phosphate then enters the glycolytic pathway, leading to the production of ATP and pyruvate. In summary, the glycolytic process from galactose involves a series of enzymatic reactions that convert galactose into glucose-6-phosphate, which can then enter the glycolytic pathway for energy production.'
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Protein | Definition | Taxonomy |
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Galactokinase | A galactokinase that is encoded in the genome of human. [PRO:DNx, UniProtKB:P51570] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
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2-(1,3-benzoxazol-2-ylamino)-5-spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclopentane]one | quinazolines |