Page last updated: 2024-10-24

cell wall macromolecule biosynthetic process

Definition

Target type: biologicalprocess

The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall. [GOC:go_curators]

Cell wall macromolecule biosynthetic process is a fundamental biological process that involves the assembly and synthesis of complex macromolecules that form the cell wall. The cell wall is a rigid, protective layer that surrounds the plasma membrane of plant, fungal, bacterial, and some algal cells. It provides structural support, protection from osmotic stress, and acts as a barrier against pathogens.

The process of cell wall macromolecule biosynthesis involves a series of coordinated steps that include:

* **Synthesis of building blocks:** Monosaccharides, amino acids, and other precursors are synthesized through metabolic pathways.
* **Transport of building blocks:** These precursors are transported across the plasma membrane to the cell wall.
* **Assembly of macromolecules:** The building blocks are assembled into complex polysaccharides, proteins, and other macromolecules.
* **Modification and deposition:** These macromolecules are modified, cross-linked, and deposited into the growing cell wall.

**Polysaccharides:**

* **Cellulose:** The most abundant structural polysaccharide in plant cell walls, cellulose is a linear polymer of glucose molecules.
* **Hemicellulose:** A group of branched polysaccharides that associate with cellulose microfibrils and provide strength and flexibility to the cell wall.
* **Pectin:** A complex polysaccharide that forms a gel-like matrix within the cell wall, contributing to cell adhesion and expansion.

**Proteins:**

* **Structural proteins:** These proteins provide structural support and maintain cell wall integrity.
* **Enzymes:** Enzymes involved in the synthesis, modification, and breakdown of cell wall components.

**Other components:**

* **Lignin:** A complex polymer that strengthens the cell wall and provides resistance to degradation.
* **Cutin:** A waxy substance that forms a protective layer on the outer surface of the cell wall.

**Regulation:**

The synthesis and assembly of cell wall macromolecules are tightly regulated by a complex network of signaling pathways and transcription factors. These regulatory mechanisms ensure that the cell wall is properly formed and maintained, and that it can adapt to changing environmental conditions.'
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Proteins (1)

ProteinDefinitionTaxonomy
Phospho-N-acetylmuramoyl-pentapeptide-transferaseA phospho-N-acetylmuramoyl-pentapeptide-transferase that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A6W3]Escherichia coli K-12

Compounds (2)

CompoundDefinitionClassesRoles
phenylalanine arginine beta-naphthylamidephenylalanine arginine beta-naphthylamide: a drug efflux pump inhibitor; structure in first sourcepeptide
capuramycincapuramycin: from Streptomyces griseus 446-S3; structure given in first source