cell adhesion involved in single-species biofilm formation

Definition

Target type: biologicalprocess

The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species. [GOC:dph, GOC:jl, GOC:tb]

Single-species biofilm formation is a complex process involving multiple steps, beginning with the initial attachment of bacteria to a surface. This attachment can be reversible or irreversible and is often mediated by weak interactions like electrostatic forces or van der Waals forces. Once attached, bacteria can begin to produce an extracellular matrix, primarily composed of polysaccharides, proteins, and DNA. This matrix helps to strengthen the biofilm, providing structural integrity and promoting cell-cell interactions. The matrix also acts as a barrier, protecting the biofilm from environmental stresses and predators. Bacteria within the biofilm can also communicate with each other through quorum sensing, a system where cells release and respond to signaling molecules. This communication allows bacteria to coordinate their activities, such as the production of matrix components and the expression of specific genes. As the biofilm matures, it can develop a complex architecture with distinct microenvironments, leading to the formation of channels and gradients in nutrient availability and oxygen concentration. This complex structure can contribute to the persistence and resilience of the biofilm, allowing it to survive in challenging environments.'
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Proteins (1)

Compounds (2)