glycoside metabolic process

Definition

Target type: biologicalprocess

The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. [ISBN:0198547684]

Glycoside metabolic process encompasses a complex series of enzymatic reactions involved in the biosynthesis, modification, and degradation of glycosides. Glycosides are molecules composed of a sugar moiety (glycone) linked to a non-sugar moiety (aglycone) via a glycosidic bond. These molecules play crucial roles in diverse biological functions, including cell signaling, energy storage, and defense mechanisms. The glycoside metabolic process begins with the formation of glycosidic bonds between sugar and non-sugar molecules through the action of glycosyltransferases. These enzymes utilize nucleotide sugars, such as UDP-glucose and GDP-mannose, as donor substrates to transfer sugar residues onto acceptor molecules. The process of glycoside biosynthesis is highly regulated and involves intricate interactions between different enzymes and regulatory proteins. Once formed, glycosides can undergo further modifications, such as phosphorylation, sulfation, or acetylation. These modifications can alter the properties of glycosides and influence their biological activities. The breakdown of glycosides is catalyzed by hydrolases, such as glycosidases. These enzymes cleave the glycosidic bond, releasing the sugar and aglycone moieties. The products of glycoside degradation can be further metabolized or utilized for other cellular processes. The glycoside metabolic process is essential for maintaining cellular homeostasis and coordinating various biological functions. Disruptions in this pathway can lead to a range of metabolic disorders and diseases. Understanding the intricacies of glycoside metabolism is crucial for developing therapeutic strategies for treating these conditions.'
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Proteins (1)

Compounds (3)