triterpenoid biosynthetic process

Definition

Target type: biologicalprocess

The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units. [GOC:go_curators]

Triterpenoid biosynthesis is a complex metabolic pathway that produces a diverse array of compounds known as triterpenoids. These molecules are ubiquitous in nature and play crucial roles in plant defense, signaling, and human health. The biosynthesis of triterpenoids typically begins with the condensation of two molecules of isopentenyl diphosphate (IPP) and one molecule of dimethylallyl diphosphate (DMAPP) to form geranyl diphosphate (GPP). GPP is then further processed through a series of enzymatic reactions to produce squalene, a 30-carbon precursor to triterpenoids. The cyclization of squalene is catalyzed by a family of enzymes known as oxidosqualene cyclases, which produce a variety of cyclic triterpenoid skeletons. These skeletons serve as the foundation for the synthesis of a wide range of triterpenoids with diverse structures and functions. The biosynthesis of triterpenoids is highly regulated by a network of transcription factors, enzymes, and environmental cues, ensuring the production of the appropriate molecules in response to specific developmental and physiological demands.'
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Proteins (1)

Compounds (2)