Roles > cathepsin L (EC 3.4.22.15) inhibitor
Page last updated: 2024-08-05 15:39:48
cathepsin L (EC 3.4.22.15) inhibitor
An EC 3.4.22.* (cysteine endopeptidase) inhibitor which interferes with the action of cathepsin L (EC 3.4.22.15).
ChEBI ID: 70821
Members (3)
Member | Definition | Class |
benzyloxycarbonylphenylalanylphenylalanine diazomethyl ketone | A diazo compound that is L-phenylalanyl-L-phenylalanine in which the amino group is protected by a (benzyloxy)carbonyl group and the carboxy group is substituted by a diazoacetyl group. It is a cathepsin L inhibitor. | Z-Phe-Phe-CHN2 |
sid 26681509 | A carbohydrazide that is L-tryptophan in which the amino and carboxy groups are substituted by tert-butoxycarbonyl and 2-({[2-(2-ethylanilino)-2-oxoethyl]sulfanyl}carbonyl)hydrazinyl groups, respectively. It is a potent and reversible inhibitor of human cathepsin L (IC50 = 56 nM). | SID 26681509 |
tln 4601 | | diazepinomicin |
Research
Studies (29)
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
pre-1990 | 5 (17.24) | 18.7374 |
1990's | 5 (17.24) | 18.2507 |
2000's | 8 (27.59) | 29.6817 |
2010's | 8 (27.59) | 24.3611 |
2020's | 3 (10.34) | 2.80 |
Study Types
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
Trials | 1 (3.45%) | 5.53% |
Reviews | 2 (6.90%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 26 (89.66%) | 84.16% |
Protein Targets (2)
Inhibition Measurements