Any compound that binds and activates the enzyme carbamylphosphate synthetase I.
ChEBI ID: 71033
| Member | Definition | Class |
|---|---|---|
| carglumic acid | A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. | carglumic acid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (4.80) | 18.7374 |
| 1990's | 9 (7.20) | 18.2507 |
| 2000's | 15 (12.00) | 29.6817 |
| 2010's | 74 (59.20) | 24.3611 |
| 2020's | 21 (16.80) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 18 (13.95%) | 5.53% |
| Reviews | 6 (4.65%) | 6.00% |
| Case Studies | 39 (30.23%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 66 (51.16%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| GALC protein | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |