Roles > EC 6.1.1.4 (leucine--tRNA ligase) inhibitor
Page last updated: 2024-08-05 15:48:31
EC 6.1.1.4 (leucine--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucine--tRNA synthetase (EC 6.1.1.4).
ChEBI ID: 77953
Members (1)
| Member | Definition | Class |
|---|
| tavaborole | A member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails). | tavaborole |
Research
Studies (72)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (8.33) | 29.6817 |
| 2010's | 56 (77.78) | 24.3611 |
| 2020's | 10 (13.89) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 9 (12.00%) | 5.53% |
| Reviews | 21 (28.00%) | 6.00% |
| Case Studies | 1 (1.33%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 44 (58.67%) | 84.16% |
Protein Targets (5)
Inhibition Measurements
Activation Measurements