Any EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor that interferes with the action of a triose-phosphate isomerase (EC 5.3.1.1).
ChEBI ID: 90691
Member | Definition | Class |
---|---|---|
phosphoglycolohydroxamate | The hydroxamate of phosphoglycolic acid. | phosphoglycolohydroxamic acid |
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
---|---|---|
pre-1990 | 1 (3.57) | 18.7374 |
1990's | 10 (35.71) | 18.2507 |
2000's | 9 (32.14) | 29.6817 |
2010's | 8 (28.57) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 28 (100.00%) | 84.16% |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
Chain A, Methylglyoxal Synthase | Escherichia coli | Ki | 0.0390 | 1 | 1 |
Chain B, TRIOSEPHOSPHATE ISOMERASE | Trypanosoma brucei brucei | Ki | 4.0000 | 1 | 1 |
Chain F, Methylglyoxal Synthase | Escherichia coli | Ki | 0.0390 | 1 | 1 |
Fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Ki | 1.0000 | 1 | 1 |
Fructose-bisphosphate aldolase class 2 | Escherichia coli K-12 | Ki | 0.0100 | 1 | 1 |
Triosephosphate isomerase | Homo sapiens (human) | Ki | 3.5000 | 2 | 2 |