An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of beta-N-acetylhexosaminidase (EC 2.3.2.52).
ChEBI ID: 184301
| Member | Definition | Class |
|---|---|---|
| 2-acetamido-2-deoxy-d-glucono-(1,5)-lactone | A deoxygluconolactone that results from the cyclisation and formal condensation of the carboxy group of 2-amino-2-deoxy-D-gluconic acid with its 5-hydroxy group. It is a sex pheromone found in the urine of female blue crabs, Callinectes sapidus. | N-acetyl-D-glucosamino-1,5-lactone |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, Hyaluronoglucosaminidase | Oceanicola granulosus HTCC2516 | IC50 | 11.0000 | 1 | 1 |