Roles > EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor
Page last updated: 2024-08-05 15:37:23

EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor

Any EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that inhibits the action of aspartate-semialdehyde dehydrogenase (EC 1.2.1.11).

ChEBI ID: 145814

Members (1)

MemberDefinitionClass
cystineThe L-enantiomer of the sulfur-containing amino acid cystine.L-cystine zwitterion; L-cystine

Research

Studies (10)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's6 (60.00)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%

Protein Targets (12)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
AR proteinHomo sapiens (human)Potency0.002411
DNA polymerase kappa isoform 1Homo sapiens (human)Potency29.934911
GLI family zinc finger 3Homo sapiens (human)Potency0.267222
heat shock protein beta-1Homo sapiens (human)Potency0.256322
Histone H2A.xCricetulus griseus (Chinese hamster)Potency0.619322
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency0.301111
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency0.301111
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency0.375811
progesterone receptorHomo sapiens (human)Potency0.334911
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency0.223134
retinoid X nuclear receptor alphaHomo sapiens (human)Potency0.301122
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency0.301111