Roles > EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor
Page last updated: 2024-08-05 14:59:48
EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor
Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of alkane 1-monooxygenase (EC 1.14.15.3).
ChEBI ID: 142481
Members (1)
| Member | Definition | Class |
|---|
| 17-octadecynoic acid | An acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid. | octadec-17-ynoic acid |
Research
Studies (99)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 2 (2.02) | 18.7374 |
| 1990's | 33 (33.33) | 18.2507 |
| 2000's | 45 (45.45) | 29.6817 |
| 2010's | 16 (16.16) | 24.3611 |
| 2020's | 3 (3.03) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 103 (100.00%) | 84.16% |
Protein Targets (13)
Potency Measurements
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Cytochrome P450 4F2 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |