Page last updated: 2024-10-06

vitamin B6 degradation

Proteins (10)

ProteinSynonymsTaxonomy
Pyridoxamine--pyruvate transaminaseEC 2.6.1.30; Pyridoxamine-pyruvate aminotransferaseMesorhizobium japonicum MAFF 303099
3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylaseHMPDdc; EC 4.1.1.51Mesorhizobium japonicum MAFF 303099
Pyridoxal 4-dehydrogenasetPLDH; EC 1.1.1.107Mesorhizobium japonicum MAFF 303099
4-pyridoxate dehydrogenaseEC 1.1.99.42; 4-pyridoxic acid dehydrogenase; 4-PADHMesorhizobium japonicum MAFF 303099
4-pyridoxolactonaseEC 3.1.1.27Mesorhizobium japonicum MAFF 303099
5-formyl-3-hydroxy-2-methylpyridine 4-carboxylate 5-dehydrogenaseFHMPC dehydrogenase; EC 1.2.1.100Mesorhizobium japonicum MAFF 303099
2-(acetamidomethylene)succinate hydrolaseEC 3.5.1.29; alpha-(N-acetylaminomethylene)succinic acid amidohydrolase; AAMS amidohydrolaseMesorhizobium japonicum MAFF 303099
2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase Pseudomonas sp. MA-1
2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenaseMesorhizobium japonicum MAFF 303099
Probable dehydrogenaseMesorhizobium japonicum MAFF 303099

Compounds (17)

CompoundDescription
hydronium ion
pyridoxalThe 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
pyridoxineThe 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
NADH
Ammonium
MercuryA silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
5-pyridoxic acid lactonestructure in first source
4-pyridoxic acid lactone
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)