Page last updated: 2024-10-06

biosynthesis of serotonin and melatonin

Proteins (4)

ProteinSynonymsTaxonomy
Aromatic-L-amino-acid decarboxylaseAADC; EC 4.1.1.28; DOPA decarboxylase; DDCMus musculus (house mouse)
Serotonin N-acetyltransferaseSerotonin acetylase; EC 2.3.1.87; Aralkylamine N-acetyltransferase; AA-NATMus musculus (house mouse)
Tryptophan 5-hydroxylase 2EC 1.14.16.4; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2Mus musculus (house mouse)
Tryptophan 5-hydroxylase 1EC 1.14.16.4; Tryptophan 5-monooxygenase 1Mus musculus (house mouse)

Compounds (7)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
melatoninA biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
SerotoninA biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Coenzyme A
n-acetylserotonin